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Identification
Molecular formula
C23H29NO2
CAS number
71827-04-4
IUPAC name
ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate
State
State

At room temperature, ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate is typically in a solid state. Its solid form is often a suitable form for its application in medicinal chemistry.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
329.45g/mol
Molar mass
329.4510g/mol
Density
1.2000g/cm3
Appearence

The appearance of ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate is typically in the form of white to off-white crystalline powder. It may also be available in tablet or capsule forms for pharmaceutical use, as it's an active pharmaceutical ingredient.

Comment on solubility

Solubility of Ethyl 1-[2-(4-Aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate

The solubility of ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate is an intriguing feature of this compound, influenced by its structural characteristics. Here are some important points to consider:

  • Polarity: The presence of both polar and non-polar groups in this compound suggests a degree of complexity in its solubility profile. Polar components may enhance solubility in aqueous solutions, while non-polar regions may favor organic solvents.
  • Solvent Interactions: This compound may display varying solubility in different solvents. It could be soluble in alcohols and chlorinated solvents, due to the potential for hydrogen bonding and dipole-dipole interactions.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature, making it essential to consider the thermal conditions for applications involving this compound.
  • pH Influence: Given the presence of the aminophenyl group, the compound's solubility might also be pH-dependent, with higher solubility at alkaline conditions.

As a general observation, it is often said that “like dissolves like,” and this principle plays a key role in predicting solubility behavior. Therefore, understanding the precise interactions between this compound and various solvents can aid in determining its solubility characteristics in practical applications.


Interesting facts

Interesting Facts about Ethyl 1-[2-(4-Aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate

Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate, commonly referred to in research settings, is a fascinating compound whose structure suggests several potential applications, particularly in the fields of medicinal chemistry and pharmacology.

Key Attributes:

  • Multi-functional Structure: The compound features a complex piperidine ring that is integrated with an ethyl group and an amino-substituted phenyl moiety. This unique structure is indicative of its potential biological activity.
  • Pharmacological Interest: Compounds similar to this one often display interactions with neurotransmitter systems, making them candidates for further investigation in the treatment of psychiatric disorders.
  • Derivative Exploration: As a derivative of piperidine, it opens the door for researchers to modify various parts of the molecule, potentially leading to enhanced pharmacological properties or reduced side effects.

Applications and Research:

This compound falls under the umbrella of materials studied for their therapeutic potential. Scientists often investigate similar compounds for:

  • Analgesic effects: Understanding how these compounds can influence pain pathways.
  • Neuropharmacology: Exploring the role of neurotransmitter modulation in various neurological conditions.
  • Drug Development: Serving as a scaffold for developing new drugs that can offer better efficacy and safety profiles.

In summary, ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-piperidine-4-carboxylate is not just a mere compound; it is a building block for future innovations in drug design, with a promise of significant contributions to therapeutic sciences.

Synonyms
ANILERIDINE
Alidine
Leritin
Nipecotan
Adopol
Apidol
Anileridina
Leritine
Anileridinum
144-14-9
Apodol
Anileridinum [INN-Latin]
Anileridina [INN-Spanish]
Ethyl 1-(p-aminophenethyl)-4-phenylisonipecotate
ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
N-beta-(p-Aminophenyl)ethylnormeperidine
Ethyl 1-(4-aminophenethyl)-4-phenylisonipecotate
N-(beta-(p-Aminophenyl)ethyl)-4-phenyl-4-carbethoxypiperidine
Ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylate
IDS-NA-012
DTXSID8022610
CHEBI:61203
4-Piperidinecarboxylic acid, 1-(2-(4-aminophenyl)ethyl)-4-phenyl-, ethyl ester
ANILERIDINE [MI]
ANILERIDINE [INN]
ANILERIDINE [HSDB]
Isonipecotic acid, 1-(p-aminophenethyl)-4-phenyl-, ethyl ester
71Q1A3O279
1-(p-Aminophenethyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester
ANILERIDINE [MART.]
1-[2-(4-Aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester
ANILERIDINE [WHO-DD]
4-Piperidinecarboxylic acid, 1-[2-(4-aminophenyl)ethyl]-4-phenyl-, ethyl ester
DTXCID702610
ANILERIDINE [USP IMPURITY]
ANILERIDINE (MART.)
ANILERIDINE (USP IMPURITY)
1-P-AMINOPHENETHYL-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
Anileridine (1.0 mg/mL in ethyl acetate)
HSDB 3288
Anileridine (USP/INN)
Anileridine [USP:INN:BAN]
ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenylpiperidine-4-carboxylate
1-(p-Aminophenethyl)-4-phenylisonipecotic acid ethyl ester
DEA No. 9020
1-(2-(4-Aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxlic acid ethyl ester
UNII-71Q1A3O279
Leritine (Canada)
1-(2-(4-Aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylic acid ethyl ester
SCHEMBL26333
GTPL7115
CHEMBL1201347
N01AH05
LKYQLAWMNBFNJT-UHFFFAOYSA-N
Tox21_113744
AKOS027446331
DB00913
NCGC00253613-01
CAS-144-14-9
NS00067931
D02941
L000700
Q742266
Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxylate #