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Fesoterodine trihydrochloride

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Identification
Molecular formula
C26H37Cl3N2O3
CAS number
286930-03-8
IUPAC name
ethyl 1-[2-(4-methylpiperazin-1-yl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate;trihydrochloride
State
State

At room temperature, Fesoterodine trihydrochloride is in a solid state.

Melting point (Celsius)
186.00
Melting point (Kelvin)
459.20
Boiling point (Celsius)
252.30
Boiling point (Kelvin)
525.50
General information
Molecular weight
527.99g/mol
Molar mass
527.9860g/mol
Density
1.2000g/cm3
Appearence

Fesoterodine trihydrochloride typically appears as a white to off-white powder. It is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility Overview

The compound ethyl 1-[2-(4-methylpiperazin-1-yl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate; trihydrochloride exhibits interesting solubility characteristics, as it is typically classified as a salt. This classification has a significant impact on its solubility in various solvents.

Key Points on Solubility

  • Water Solubility: As a trihydrochloride salt, this compound is likely to be highly soluble in water, which is common for many ionic compounds. This high solubility can be attributed to the presence of multiple hydrochloride groups that facilitate interactions with water molecules.
  • Solvent Specificity: The solubility of this compound may vary considerably in organic solvents. For instance, it may exhibit limited solubility in non-polar solvents like hexane or toluene due to its polar nature.
  • Temperature Dependence: Solubility is often temperature-dependent. This compound may have increased solubility at elevated temperatures, which can be relevant during dissolution processes.
  • pH Influence: Since this compound carries multiple ionizable groups, its solubility can also be affected by the pH of the solution. Changes in pH can lead to protonation or deprotonation events, which can enhance or hinder solubility.

As a general statement, environments that favor charge stabilization—such as aqueous solutions—are where this compound is expected to be most soluble. Understanding the solubility of ethyl 1-[2-(4-methylpiperazin-1-yl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate; trihydrochloride is crucial for its applications in various fields, particularly in pharmaceuticals, where solubility significantly influences bioavailability and efficacy.

Interesting facts

Interesting Facts About Ethyl 1-[2-(4-methylpiperazin-1-yl)-2-phenyl-ethyl]-4-phenyl-piperidine-4-carboxylate;tri hydrochloride

This compound is a complex organic molecule that belongs to the class of piperidine derivatives, renowned for their diverse applications in medicinal chemistry. Here are some key highlights:

  • Pharmacological Potential: Due to its structure, this compound is of particular interest in the field of pharmaceuticals, especially for its potential roles in therapeutic agents targeting neurological disorders.
  • Piperazine Core: The presence of piperazine rings in the compound enhances its biological activity and can play a critical role in the modulation of neurotransmitter systems.
  • Structural Variability: This molecule showcases intriguing structural features, including a phenyl substitution that can influence its affinity to various biological targets, making it a subject of study for drug design.
  • Chloride Salts: The tri hydrochloride form of this compound can improve its solubility and bioavailability, crucial factors in the development of effective pharmaceutical formulations.
  • Research Applications: Scientists are examining compounds like this for their properties in enhancing cognitive functions, providing broader insights into their mechanisms of action and efficacy in clinical applications.

The study of such complex molecules leads to exciting possibilities, and their multifaceted nature can provide chemists with valuable insights into developing new drugs. As researchers continue to explore the potential of piperidine and piperazine derivatives, one can anticipate innovative breakthroughs that enhance our understanding of chemical interactions and biological processes.

Synonyms
13451-62-2
Isonipecotic acid, 1-(beta-(4-methyl-1-piperazinyl)phenethyl)-4-phenyl-, ethyl ester, trihydrochloride
DTXSID30928642
Ethyl 1-[2-(4-methylpiperazin-1-yl)-2-phenylethyl]-4-phenylpiperidine-4-carboxylate--hydrogen chloride (1/3)