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Ethyl 1-(2-phenoxyethyl)-4-phenylpiperidin-1-ium-4-carboxylate bromide

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Identification
Molecular formula
C22H28BrNO3
CAS number
72875-16-6
IUPAC name
ethyl 1-(2-phenoxyethyl)-4-phenyl-piperidin-1-ium-4-carboxylate;bromide
State
State

At room temperature, ethyl 1-(2-phenoxyethyl)-4-phenylpiperidin-1-ium-4-carboxylate bromide is usually in a solid state, appearing as crystalline powder. It is not volatile under standard conditions.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
432.37g/mol
Molar mass
432.3150g/mol
Density
1.2000g/cm3
Appearence

This compound typically appears as a solid crystalline powder that can vary in color from white to off-white. Its form and purity can affect its appearance, potentially making it appear slightly yellowish if there are impurities present.

Comment on solubility

Solubility of Ethyl 1-(2-phenoxyethyl)-4-phenyl-piperidin-1-ium-4-carboxylate Bromide

The solubility of ethyl 1-(2-phenoxyethyl)-4-phenyl-piperidin-1-ium-4-carboxylate bromide is an intriguing aspect of its chemical behavior. This compound, being an ionic species due to the presence of the bromide anion, tends to exhibit significant solubility in polar solvents. Here are some key points to consider:

  • Polar Solvents: This compound is highly soluble in water and polar organic solvents like methanol and ethanol. The ionic character allows for favorable interactions with water molecules, enhancing solubility.
  • Non-Polar Solvents: In contrast, it shows low solubility in non-polar solvents such as hexane or toluene. The hydrophobic phenyl groups can disrupt solubility in these media.
  • Temperature Dependency: Solubility may also increase with temperature, a common trend observed in ionic compounds. Higher temperatures tend to enhance molecular movement and solvation dynamics.
  • pH Influence: The solubility can be affected by the pH of the medium, where acidic or basic conditions could lead to alterations in ionic form, impacting solubility behavior.

As the solubility characteristics of this compound suggest, understanding the molecular interactions is crucial for its application in various chemical environments. The dynamics of solubility not only determine its practical utility but also influence its reactivity in diverse scenarios.

Interesting facts

Interesting Facts about Ethyl 1-(2-phenoxyethyl)-4-phenyl-piperidin-1-ium-4-carboxylate Bromide

This compound is a fascinating example of a quaternary ammonium salt, showcasing unique properties due to its complex structure. It emerges as a synthetic derivative of piperidine, a key building block in medicinal chemistry. The presence of a phenoxy group adds an aromatic character, enhancing the compound's bioactivity.

Potential Applications

As a compound derived from piperidine, it may exhibit:

  • Pharmaceutical Potential: Compounds containing piperidine rings often play critical roles in drug design, particularly in developing analgesics and antidepressants.
  • Neuroactive Properties: Similar structures have been investigated for their potential effects on neurotransmitter systems, potentially influencing cognitive functions.
  • Agonist Activity: The unique functional groups present in this molecule might offer agonistic activity at various receptor sites.

Research Insights

Research continues to explore:

  • Synthesis Techniques: Innovative synthetic methods are being investigated to improve yields and reduce environmental impact.
  • Structure-Activity Relationships (SAR): Scientists analyze how variations in the molecular structure influence biological activity, paving the way for targeted drug development.
  • Toxicology Studies: Understanding the safety profile is crucial, as with all compounds that have the potential for biological activity.

In essence, ethyl 1-(2-phenoxyethyl)-4-phenyl-piperidin-1-ium-4-carboxylate bromide presents an exciting avenue for both research and application in the field of chemistry, exemplifying how intricacies in structure can play critical roles in functionality and therapeutic potential.

Synonyms
1-(2-Phenoxyethyl)-4-phenylisonipecotic acid ethyl ester hydrobromide
18729-31-2
TA 27
ISONIPECOTIC ACID, 1-(2-PHENOXYETHYL)-4-PHENYL-, ETHYL ESTER, HYDROBROMIDE