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Ethylnorephedrine

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Identification
Molecular formula
C23H28N2O2
CAS number
21833-83-2
IUPAC name
ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate
State
State

Solid

Melting point (Celsius)
195.50
Melting point (Kelvin)
468.70
Boiling point (Celsius)
411.50
Boiling point (Kelvin)
684.70
General information
Molecular weight
352.48g/mol
Molar mass
352.4700g/mol
Density
1.0829g/cm3
Appearence

Ethylnorephedrine appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of Ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate

The solubility of ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate is influenced by several factors due to its complex chemical structure. Understanding its solubility can provide insights into its potential applications and behavior in various environments.

  • Polarity: The presence of both hydrophobic (the phenyl and piperidine groups) and hydrophilic (the carboxylate and ethyl groups) components contributes to the overall polarity of the compound. This dual nature often results in variable solubility in different solvents.
  • Solvent Interaction:
    • Water: The solubility in water may be limited due to the hydrophobic characteristics, making it less soluble in aqueous solutions.
    • Organic Solvents: This compound is more likely to dissolve in organic solvents such as ethanol or methanol due to similar polar and non-polar properties.
  • Temperature Effects: Increased temperature can enhance solubility for many organic compounds, so assessing the solubility at varying temperatures may reveal more about the solubility profile of this particular compound.

Overall, the solubility of ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate is not straightforward. As highlighted, the interplay of structural features and environmental factors leads to a nuanced understanding of its behavior in different solvents.

Interesting facts

Interesting Facts about Ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate

Ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate is a fascinating compound that belongs to the class of piperidine derivatives. This compound is of particular interest due to its potential applications in medicinal chemistry, specifically in the development of pharmacological agents.

Key Characteristics

  • Structure and Function: The unique piperidine core combined with an anilinopropyl group allows for interesting interactions with biological targets, making it a subject of research in drug discovery.
  • Pharmacological Significance: Compounds like this one have shown promise in therapeutic areas such as analgesics and psychoactive drugs, indicative of the versatility found in piperidine derivatives.
  • Research Interest: Ongoing studies are focusing on how subtle changes in the chemical structure of such compounds can influence their efficacy and safety profile in medicinal contexts.

Potential Applications

This compound has been studied for various potential applications, including:

  • As an *analgesic agent*, offering new avenues for pain management.
  • In the development of new *antidepressant medications*, capitalizing on its interaction with central nervous system receptors.
  • Studies are exploring its role in combating *neurodegenerative diseases*, showcasing the importance of piperidine frameworks in neurological health.

As a chemistry student or scientist, understanding the *intricacies of such compounds* is essential. The relationships between chemical structure and biological activity underscore the complexity and excitement within the field of medicinal chemistry. Whether delving into synthesis, characterizing properties, or studying biological effects, compounds like ethyl 1-(3-anilinopropyl)-4-phenyl-piperidine-4-carboxylate provide a rich landscape for exploration and discovery.

Synonyms
PIMINODINE
Anopridine
Pimadine
Cimadon
Pimadin
Pimadin (analgesic)
Alvodine
Piminodina
13495-09-5
Piminodinum
Piminodine [INN:BAN]
Piminodinum [INN-Latin]
Piminodina [INN-Spanish]
NIH 7590
WIN 14098
WIN 14098-2
3IIX447HWS
EINECS 236-817-6
BRN 0334632
4-Piperidinecarboxylic acid, 4-phenyl-1-(3-(phenylamino)propyl)-, ethyl ester
IDS-NP-012
Isonipecotic acid, 1-(3-anilinopropyl)-4-phenyl-, ethyl ester
PIMINODINE [MI]
PIMINODINE [INN]
5-22-02-00490 (Beilstein Handbook Reference)
PIMINODINE [WHO-DD]
4-Phenyl-1-(3-(phenylamino)propyl)-4-piperidinecarboxylic acid ethyl ester
DTXSID60159149
Piminodine (INN)
Piminodinum (INN-Latin)
Piminodina (INN-Spanish)
4-Piperidinecarboxylic acid, 4-phenyl-1-[3-(phenylamino)propyl]-, ethyl ester
DTXCID4081640
Isonipecotic acid, 1-(3-anilinopropyl)-4-phenyl-, ethyl ester (7CI,8CI)
ethyl 1-(3-(phenylamino)propyl)-4-phenylpiperidine-4-carboxylate
236-817-6
UNII-3IIX447HWS
DEA No. 9730
Piminodin
ethyl 1-(3-anilinopropyl)-4-phenylpiperidine-4-carboxylate
SCHEMBL26477
CHEMBL2110995
CHEBI:135546
HY-U00297
CS-7266
PIMINODINE ALVODINE,PIMADIN,CIMAPON
NS00010500
D12683
Q7194651
Ethyl 1-(3-anilinopropyl)-4-phenyl-4-piperidinecarboxylate #