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Etofylline

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Identification
Molecular formula
C19H23NO3
CAS number
85-43-8
IUPAC name
ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate
State
State

At room temperature, Etofylline is a solid compound. It is typically provided in its pure form as a crystalline powder for use in pharmaceutical formulations.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
405.54g/mol
Molar mass
405.5400g/mol
Density
1.1000g/cm3
Appearence

Etofylline typically appears as white or almost white crystalline powder and it is odorless. It is soluble in water and organic solvents.

Comment on solubility

Solubility of Ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate

When assessing the solubility of ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate, we must consider several factors that influence its behavior in various solvents.

Factors Influencing Solubility

  • Polarity: The compound contains both polar and nonpolar functional groups, which can lead to varied solubility in different solvents.
  • Hydrogen Bonding: The presence of the -OH group suggests potential for hydrogen bonding, masking a tendency toward higher solubility in polar solvents such as water.
  • Hydrophobic Regions: The phenyl and piperidine rings are hydrophobic, which may enhance solubility in organic solvents like ethanol and methanol.

Depending on the polarity of the solvent, the solubility of this compound can vary:

  • High solubility: in polar organic solvents.
  • Low solubility: in nonpolar solvents.

In summary, the solubility of ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate is significantly influenced by its structural attributes, allowing it to show varied solubility characteristics that can be exploited in a variety of chemical applications.

Interesting facts

Interesting Facts about Ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate

Ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate is an intriguing compound that falls within the realm of pharmaceuticals and organic chemistry. This compound is primarily known for its potential applications in medical science, particularly in developing analgesic and anti-inflammatory agents. Here are some key insights into this fascinating compound:

  • Structure and Function: The molecule contains a piperidine ring, which is a characteristic feature in many drugs. The presence of both ethyl and phenyl groups contributes to its complex interactions within biological systems.
  • Pharmacological Potential: Due to its structural configuration, this compound may exhibit unique properties that can lead to innovative therapeutic applications. Research is ongoing to fully understand its effects and mechanisms of action.
  • Synthesis: The synthesis of this compound involves several organic chemistry techniques, including condensation reactions and protection-deprotection strategies, showcasing the beauty and complexity of organic synthesis.
  • Research Interest: As scientists continue to explore its properties, there's significant interest in its effects on the central nervous system, making it a candidate for studying pain management solutions.
  • Development of New Drugs: Compounds like this are often precursors or inspiration for designing new medications, allowing chemists to refine their structures to enhance efficacy and reduce side effects.

In conclusion, Ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate is more than just a chemical formula; it represents a bridge between fundamental chemistry and real-world applications in health and medicine. The ongoing exploration of such compounds illustrates the importance of organic chemistry in addressing pressing medical needs.

Synonyms
PHENOPERIDINE
Fenoperidina
Fenoperidine
Phenoperidin
Phenoperidinum
Dl-phenoperidine
Fenoperidina [INN-Spanish]
Phenoperidinum [INN-Latin]
Phenoperidine [INN:BAN:DCF]
R-1406
UNII-G9BH09J4JW
EINECS 209-229-2
G9BH09J4JW
IDS-NP-010
Phenoperidine (INN)
1-(3-Hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester
4-Piperidinecarboxylic acid, 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, ethyl ester
NIH 7591
NIH-7591
PHENOPERIDINE [MI]
PHENOPERIDINE [INN]
PHENOPERIDINE [WHO-DD]
DTXSID90862199
Fenoperidina (INN-Spanish)
Phenoperidinum (INN-Latin)
1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-isonipecotic acid ethyl ester
ISONIPECOTIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER
DTXCID30810997
N01AH04
209-229-2
ipopqvvncfqfrk-uhfffaoysa-n
562-26-5
R 1406
ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate
DEA No. 9641
SCHEMBL80415
CHEMBL2105385
CHEBI:135550
DB13605
NS00042807
D02611
Q7181394
Ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-piperidinecarboxylate #