Skip to main content

Hydrochloride of Esterified 4-Phenylpiperidine

ADVERTISEMENT
Identification
Molecular formula
C23H30ClNO3
CAS number
746-21-0
IUPAC name
ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate;hydrochloride
State
State

At room temperature, ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate hydrochloride exists as a solid compound. Its solid state is maintained under typical conditions of temperature and pressure, and it does not easily evaporate or sublimate.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
345.88g/mol
Molar mass
345.8830g/mol
Density
1.1430g/cm3
Appearence

The compound appears as a white crystalline solid, often showing characteristic shiny crystals, typical of hydrochloride salts. It is odorless and typically supplied in powdered form.

Comment on solubility

Solubility of Ethyl 1-(3-Hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate; Hydrochloride

The solubility characteristics of ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate; hydrochloride can be quite intriguing. This compound, like many other piperidine derivatives, exhibits unique solubility properties due to its complex structure. Here are some key points regarding its solubility:

  • The hydrochloride salt form typically enhances solubility in polar solvents, such as water and alcohols, compared to its free base form.
  • It is generally soluble at room temperature, which makes it suitable for various applications, including pharmaceutical formulations.
  • Factors such as pH levels and temperature can significantly affect solubility, highlighting the importance of proper conditions during experimentation.
  • While the compound may have limited solubility in non-polar solvents (like hexane or toluene), its behavior in biological systems often favors solubility in aqueous environments.

In summary, understanding the solubility profile of this compound is essential for optimizing its use in various chemical and biological contexts. As always, one must consider the implications of solubility in relation to the desired application in research and industry.

Interesting facts

Intriguing Insights on Ethyl 1-(3-Hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate Hydrochloride

Ethyl 1-(3-hydroxy-3-phenyl-propyl)-4-phenyl-piperidine-4-carboxylate hydrochloride is a fascinating compound in the realm of organic chemistry, offering a unique structure that is of significant interest to researchers in medicinal chemistry and pharmacology. This compound belongs to the class of piperidine derivatives, which are known for their diverse biological activities.

Key Characteristics:

  • Pharmacological Relevance: The presence of the piperidine ring in its structure is linked to several pharmacological functions, including potential analgesic and anti-inflammatory effects.
  • Synthetic Versatility: This compound can serve as an intermediate in the synthesis of various pharmaceuticals, particularly those that target the central nervous system.
  • Structural Complexity: Its intricate arrangement of functional groups enhances its interaction potential with biological systems, making it an interesting subject for drug development.

Furthermore, the compound combines multiple functionalities, such as a hydroxyl group and an ester moiety, which can influence its solubility and reactivity. One of the standout features is its stereochemistry, which could be crucial for determining its biological activity. As noted by many in the field, "the efficacy of a compound is often determined by the precise arrangement of its atoms."

The hydrochloride salt form enhances its stability and solubility in aqueous solutions, further facilitating experimental studies and applications in drug formulation. Researchers continually explore the implications of such compounds, seeking to unlock their full potential in therapeutic contexts.

This compound not only represents a noteworthy example of structural innovation in organic chemistry but also serves as a testament to the ongoing exploration and optimization of compounds that could lead to groundbreaking advancements in medical science.

Synonyms
Phenoperidine hydrochloride
Phenoperidine HCl
Lealgin
3627-49-4
UNII-1D9C1OK7KZ
EINECS 222-846-1
1D9C1OK7KZ
SC-9369
Isonipecotic acid, 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
4-Phenyl-4-carbethoxy-1-(3-hydroxy-3-phenylpropyl)piperidine hydrochloride
4-Piperidinecarboxylic acid, 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, ethyl ester, HCl
PHENOPERIDINE HYDROCHLORIDE [MI]
PHENOPERIDINE HYDROCHLORIDE [WHO-DD]
Piperidine, 4-carbethoxy-1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, hydrochloride
4-Piperidinecarboxylic acid, 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
4-PIPERIDINECARBOXYLIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE (1:1)
Hydrochloride, Phenoperidine
222-846-1
Phenoperidinhydrochlorid
SCHEMBL394330
DTXSID10957657
HGEAGOBQOIMDQV-UHFFFAOYSA-N
NS00082742
Q27252275
ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate;hydrochloride
Ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate--hydrogen chloride (1/1)