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ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenylpiperidine-4-carboxylate

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Identification
Molecular formula
C25H25N3O4
CAS number
Not Available
IUPAC name
ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate
State
State

At room temperature, ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenylpiperidine-4-carboxylate is typically a solid. Its crystalline form contributes to its stability under standard conditions.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.00
Boiling point (Celsius)
453.00
Boiling point (Kelvin)
726.00
General information
Molecular weight
420.48g/mol
Molar mass
420.4830g/mol
Density
1.2000g/cm3
Appearence

Ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenylpiperidine-4-carboxylate typically appears as a solid. The compound is often crystalline in structure and can vary in color depending on purity and specific polymorphs.

Comment on solubility

Solubility of Ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate

The solubility of organic compounds is an essential property that dictates their behavior in various environments, especially in pharmaceuticals and chemical syntheses. For ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate, we can consider several factors that influence its solubility:

  • Polarity: The presence of functional groups can affect the overall polarity of the compound. The nitro group and the carboxylate moiety may enhance solubility in polar solvents like water.
  • Hydrogen Bonding: Functional groups capable of hydrogen bonding can increase solubility. The carboxylate might interact with water molecules, suggesting some degree of solubility in aqueous solutions.
  • Hydrophobic Characteristics: The phenyl and piperidine groups are more hydrophobic, which could limit solubility in water but may allow for better solubility in organic solvents.

In general, ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate may demonstrate variable solubility based on the solvent system used. As a rule of thumb, "like dissolves like," meaning that polar compounds tend to dissolve in polar solvents, whereas non-polar compounds are better suited for non-polar solvents.

Therefore, while specific solubility data may be required for precise applications, one could reasonably anticipate that this compound exhibits moderate solubility properties, with potential increased solubility in polar environments due to the presence of polar functional groups.

Interesting facts

Exploring Ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate

Ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate is an intriguing compound with numerous properties that make it a point of interest in various scientific fields. Here are some captivating aspects:

  • Pharmacological Potential: The compound features a complex structure that includes piperidine and nitro-indole moieties, often associated with neuroactive properties. This suggests potential applications in developing novel therapeutics targeting neurological disorders.
  • Diverse Applications: The combination of piperidine and indole frameworks is commonly explored in medicinal chemistry. Indoles are known for their occurrence in various biologically active compounds, thus making this compound a subject for synthesis in drug discovery.
  • Research Interest: The nitro group in the structure may play a pivotal role in *bioactivity*. Nitro-containing compounds are often investigated for anti-inflammatory, antibacterial, and anticancer activities, piquing the interest of researchers.
  • Structure-Activity Relationship: Understanding how variations in the structure of this compound affect its biological activity is vital for chemists. Such studies highlight the importance of molecular modifications in optimizing the efficacy of pharmaceutical agents.
  • Multi-Functional Groups: The presence of ester and aromatic rings in the compound suggests that it may have diverse interactions and could serve as a versatile scaffold in chemical synthesis. This opens avenues for creating derivatives with tailored biological profiles.

Ultimately, the study of ethyl 1-[(5-nitro-1H-indol-3-yl)methyl]-4-phenyl-piperidine-4-carboxylate not only contributes to the scientific community's understanding of complex organic compounds but also holds promise for the development of innovative solutions in pharmacology and beyond. As we explore its chemical and biological facets, we engage in the fascinating interplay between structure and function.