Ethyl 1-amino-4-phenylpiperidine-4-carboxylate

Identification

Molecular formula

C₁₄H₂₀N₂O₂

CAS number

5961-14-8

IUPAC name

ethyl 1-amino-4-phenyl-piperidine-4-carboxylate

State

Ethyl 1-amino-4-phenylpiperidine-4-carboxylate is a solid at room temperature.

Melting point (Celsius)

93.00

Melting point (Kelvin)

366.15

Boiling point (Celsius)

305.20

Boiling point (Kelvin)

578.35

General information

Molecular weight

262.33g/mol

Molar mass

262.3330g/mol

Density

1.1012g/cm³

Appearence

Ethyl 1-amino-4-phenylpiperidine-4-carboxylate typically appears as a crystalline solid, and its color can range from white to off-white.

Comment on solubility

Solubility of Ethyl 1-amino-4-phenyl-piperidine-4-carboxylate

Ethyl 1-amino-4-phenyl-piperidine-4-carboxylate, characterized by its complex structure, exhibits intriguing solubility properties that can be influenced by several factors. Understanding its solubility can be critical for applications in pharmaceuticals and chemical synthesis.

Solubility Characteristics

The solubility of this compound can be discussed in the following contexts:

Polarity: The presence of a carboxylate group contributes to the polar character of the molecule, often allowing for increased solubility in polar solvents such as water.
Hydrogen Bonding: The amino group in the structure enables the possibility of hydrogen bonding, which can further enhance solubility in various solvent environments.
Organic Solvents: In organic solvents like ethanol, methanol, and dichloromethane, the solubility is generally favorable due to the hydrophobic aromatic group that complements the solvent's characteristics.

To summarize, *ethanol* and *dimethyl sulfoxide (DMSO)* are examples of solvents that may dissolve this compound effectively, while its solubility in water might be moderate, impacted significantly by temperature and pH conditions. Thus, understanding the solubility profile of ethyl 1-amino-4-phenyl-piperidine-4-carboxylate is essential for effectively utilizing it in various scientific applications.

Interesting facts

Interesting Facts About Ethyl 1-Amino-4-phenyl-piperidine-4-carboxylate

The compound ethyl 1-amino-4-phenyl-piperidine-4-carboxylate belongs to a unique class of molecules known for their diverse applications in medicinal chemistry and pharmacology. Here are some intriguing insights into this chemical:

Pharmacological Relevance: This compound is part of a family of piperidine derivatives, which are often investigated for their potential use in treating various neurological disorders, including depression and anxiety. The piperidine ring is known for its ability to interact with neurotransmitter receptors in the brain.
Synthetic Pathways: The synthesis of ethyl 1-amino-4-phenyl-piperidine-4-carboxylate can involve several methodologies, including nucleophilic substitution and reduction reactions. Chemists often explore new synthetic routes to improve yield and decrease environmental impact.
Research Potential: Ongoing studies in this area focus on the optimization of the compound for enhanced activity and reduced side effects. As one researcher noted, “The exploration of piperidine derivatives is a fertile ground for discovering next-generation therapeutic agents.”
Structural Characteristics: The presence of an amino group and a phenyl ring in its structure may confer specific biochemical properties, making it an interesting subject for structure-activity relationship (SAR) studies.
Interdisciplinary Connections: This compound not only finds relevance in chemistry but also overlaps with fields like biology and pharmacology, highlighting the interconnectivity between these scientific disciplines.

In conclusion, ethyl 1-amino-4-phenyl-piperidine-4-carboxylate serves as a fascinating example of how organic compounds can be integral to advancements in medicine and our understanding of chemical biology. Its potential in therapeutic applications makes it a compound worthy of further investigation.