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Identification
Molecular formula
C15H20N4O2
CAS number
N/A
IUPAC name
ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate
State
State

This compound is in a solid state at room temperature, generally maintaining its form under standard conditions of pressure and temperature. It has a stable crystalline structure that does not easily decompose at ambient conditions.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
288.34g/mol
Molar mass
288.3360g/mol
Density
1.3500g/cm3
Appearence

Ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate is generally a crystalline solid, often appearing as a white or off-white powder. The solid is typically homogeneous and free of visible impurities.

Comment on solubility

Solubility of Ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate

The solubility characteristics of ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate (C15H20N4O2) are influenced by its complex molecular structure. Here are several key points regarding its solubility:

  • Solvent Polarity: The solubility of this compound tends to be affected by the polarity of the solvent used. Generally, polar solvents may facilitate better solubility due to the presence of functional groups that can engage in hydrogen bonding.
  • Hydrophobic Regions: The molecule comprises hydrophobic regions from the ethyl and isopropyl groups, which can limit its solubility in highly polar solvents.
  • Temperature Dependency: Solubility can vary significantly with temperature; increasing the temperature may enhance solubility by providing more energy for molecular interactions.
  • Common Solvents: This compound may exhibit solubility in common organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), though specific data may be required for precise applications.

In essence, while the solubility of ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate can be estimated based on its functional groups and structural components, empirical solubility tests in various solvents are essential for practical applications. As with many complex compounds, "understanding solubility is key to unlocking the full potential of its use."

Interesting facts

Interesting Facts About Ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate

Ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate is a fascinating compound that has garnered attention in both academic and pharmaceutical research. Here are some intriguing aspects of this complex molecule:

  • Innovative Synthesis: The synthesis of this compound involves multiple steps, including the formation of the pyrazole ring and the introduction of the hydrazine derivative, showcasing the complexity and creativity of organic synthesis.
  • Potential Biological Activity: Compounds containing the pyrazolo-pyridine scaffold have shown promising biological activities, including anti-inflammatory and anticancer properties. The unique substitutions on this compound may influence its biological activity, making it a topic of interest for drug development.
  • Versatility: This compound can be a valuable building block in medicinal chemistry due to its ability to modify pharmacokinetic properties of drugs, potentially enhancing their efficacy and reducing side effects.
  • Research Implications: Ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate can serve as a model structure in the study of structure-activity relationships (SAR) for similar compounds. Understanding how small changes in the molecular structure can affect activity is crucial for rational drug design.

In summary, this compound's intricate structure not only challenges chemists in the lab but also opens new avenues for research and development in pharmaceutical sciences. As with many complex organic molecules, the exploration of ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate promises to be rewarding, expanding our understanding of chemical interactions and therapeutic potentials.

Synonyms
etazolate
51022-77-6
Etazolato
Etazolate [INN]
Etazolatum
EHT-0202
SQ-20009
Etazolatum [INN-Latin]
Etazolato [INN-Spanish]
ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate
UNII-I89Y79062L
1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester
I89Y79062L
DTXSID4048434
CHEBI:138502
Tox21 111226
ethyl 1-ethyl-4-(2-isopropylidenehydrazino)-1h-pyrazolo[3,4-b]pyridine-5-carboxylate
1H-Pyrazolo[3,4-b]pyridine-5-carboxylicacid, 1-ethyl-4-[2-(1-methylethylidene)hydrazinyl]-, ethyl ester, hydrochloride(1:1)
SQ-20,009
Etazolatum (INN-Latin)
Etazolato (INN-Spanish)
ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate
ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[4,5-e]pyridine-5-carboxylate
Ethyl 1-ethyl-4-[2-(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl ester
Ethyl 1-ethyl-4-(2-(propan-2-ylidene)hydrazineyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
ETHYL 1-ETHYL-4-(ISOPROPYLIDENEHYDRAZINO)-1H-PYRAZOLO(3,4-B)PYRIDINE-5-CARBOXYLATE
NSC163611
SQ 20,009
Ethyl 1-ethyl-4-(2-(1-methylethylidene)hydrazino)-1H-pyrazolo(3,4-b)pyridine-5-carboxylate
ethyl 1-ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo(3,4-b)pyridine-5-carboxylate
ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo(3,4-b)pyridine-5-carboxylate
ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo(3,4-b)pyridine-5-carboxylate
ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo(4,5-e)pyridine-5-carboxylate
1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo(3,4-b)pyridinecarboxylic acid ethyl ester
Tocris-0438
Lopac-E-1896
Lopac0_000440
Etazolate hydrochloride(USAN)
SCHEMBL123840
GTPL7336
DTXCID0028408
CHEBI:93135
EHT-202
HMS2090J08
BDBM50225504
HSCI1_000299
CCG-204532
FE22846
SB16896
SDCCGSBI-0050425.P002
NCGC00015403-01
NCGC00015403-02
NCGC00015403-03
NCGC00015403-04
NCGC00024590-01
NCGC00024590-02
NS00120481
AB01275529-01
Q5402458
BRD-K64755930-003-01-6
BRD-K64755930-003-02-4
BRD-K64755930-003-03-2
1-Ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic Acid Ethyl Ester