Skip to main content

Ethyl 1-phenylpiperidine-4-carboxylate

ADVERTISEMENT
Identification
Molecular formula
C14H19NO2
CAS number
2846-35-5
IUPAC name
ethyl 1-phenylpiperidine-4-carboxylate
State
State
The compound is typically in a solid state at room temperature with a crystalline appearance.
Melting point (Celsius)
49.00
Melting point (Kelvin)
322.15
Boiling point (Celsius)
348.00
Boiling point (Kelvin)
621.15
General information
Molecular weight
233.31g/mol
Molar mass
233.3140g/mol
Density
1.0380g/cm3
Appearence

Ethyl 1-phenylpiperidine-4-carboxylate appears as a white to off-white crystalline solid. It may be visually characterized by its crystalline texture and neutral tone.

Comment on solubility

Solubility of Ethyl 1-phenylpiperidine-4-carboxylate

Ethyl 1-phenylpiperidine-4-carboxylate, a compound with diverse applications, exhibits intriguing solubility characteristics. Understanding its solubility is crucial for various chemical processes. Here are some key points regarding its solubility:

  • Solvent Compatibility: Ethyl 1-phenylpiperidine-4-carboxylate is generally soluble in organic solvents such as ethanol, methanol, and chloroform.
  • Water Solubility: This compound tends to have limited solubility in water, which is typical for many organic compounds due to their hydrophobic nature.
  • Temperature Dependency: Solubility can be influenced by temperature; in many cases, higher temperatures can enhance solubility in organic solvents.
  • Functional Groups Impact: The presence of the carboxylate group contributes to moderate solubility in polar solvents, even though the overall hydrophobic structure may hinder it.

In summary, while ethyl 1-phenylpiperidine-4-carboxylate is versatile in organic media, its limited water solubility makes it less favorable for aqueous applications. This characteristic is significant for chemists when considering solvent choices for reactions or formulations.

Interesting facts

Interesting Facts about Ethyl 1-Phenylpiperidine-4-Carboxylate

Ethyl 1-phenylpiperidine-4-carboxylate is a fascinating compound that belongs to the family of piperidine derivatives. It has garnered attention in the fields of medicinal chemistry and pharmacology for several reasons:

  • Pharmacological Potential: This compound and its derivatives may exhibit unique biological activities, making them subjects of interest for developing novel pharmaceuticals. Research suggests they might have potential as analgesics or in treatments related to neurological disorders.
  • Synthetic Utility: Ethyl 1-phenylpiperidine-4-carboxylate can serve as a valuable intermediate in organic synthesis. Its structure allows for various modifications that can lead to the creation of diverse chemical entities.
  • Structural Diversity: The presence of both the ethyl ester and the piperidine ring contributes to its complexity, which is essential when studying structure-activity relationships (SAR) in drug design.
  • Chemical Family: As a member of the piperidine family, it shares characteristics with other important compounds, such as morphine and nicotine, which also contain piperidine moieties.
  • Research Scope: Ongoing studies may explore its role in receptor binding and inhibition, which could shed light on its mechanism of action in biological systems.

As we continue to explore this intriguing compound, it's essential to note how innovations in synthesis and screening techniques can accelerate the discovery of new medicinal applications. The interplay of chemistry and biology in this compound exemplifies the exciting possibilities in the realm of organic and medicinal chemistry.

In the words of a famous chemist, "The beauty of chemistry lies in its ability to transform one compound into another, creating new possibilities," a sentiment that holds true for ethyl 1-phenylpiperidine-4-carboxylate and its potential journeys in scientific exploration.

Synonyms
Ethyl 1-phenylpiperidine-4-carboxylate
247022-37-3
4-Piperidinecarboxylic acid, 1-phenyl-, ethyl ester
4-Carbethoxy-1-phenylpiperidine
Ethyl1-phenylpiperidine-4-carboxylate
MFCD21609276
SCHEMBL5913512
DTXSID20274483
ZNOCPXFFJBMLLC-UHFFFAOYSA-N
AKOS016002653
WS-02253
CS-0323887
W18591