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Flecainide

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Identification
Molecular formula
C17H20F3NO2
CAS number
54143-55-4
IUPAC name
ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate
State
State

At room temperature, flecainide is in a solid-state, most commonly appearing as a fine, white to off-white powder.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.00
Boiling point (Celsius)
508.80
Boiling point (Kelvin)
781.90
General information
Molecular weight
487.96g/mol
Molar mass
487.9600g/mol
Density
1.1521g/cm3
Appearence

Flecainide is typically a white to off-white crystalline powder. It is often found in the form of its acetate salt for pharmaceutical applications.

Comment on solubility

Solubility of Ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate

The solubility of ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate can be quite fascinating, considering its structural characteristics. Here are some important aspects regarding its solubility:

  • Polarity: The presence of functional groups in the compound, especially the ethyl and amino functionalities, contributes to its polar nature, potentially enhancing its solubility in polar solvents, such as water.
  • Hydrophobic Regions: The trifluoromethyl group on the phenyl ring introduces a degree of hydrophobic character, which may affect solubility in water, often resulting in better solubility in organic solvents like ethanol or methanol.
  • Temperature Effects: The solubility may increase with temperature, as is common with many organic compounds. This can lead to improved dissolution rates in various solvents.
  • pH Dependency: The solubility of the compound could also be influenced by pH levels, especially due to the acidic or basic nature of the amino group, which may lead to protonation or deprotonation in different environments.

In conclusion, the solubility of ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate is a multifactorial phenomenon influenced by its structural features, leading to different solubility profiles in various solvents. Understanding these aspects can significantly aid in its application and utilization in both research and industry.

Interesting facts

Interesting Facts about Ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate

Ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate, often referred to as a complex organic molecule, is noteworthy for several reasons:

  • Pharmaceutical Applications: This compound is significant in the field of medicinal chemistry. It has the potential to be developed into pharmaceuticals targeting various diseases.
  • Fluorine Substitution: The presence of a trifluoromethyl group is particularly interesting. Fluorine atoms can drastically alter the chemical properties of organic molecules, often enhancing their efficacy as drugs and improving metabolic stability.
  • Structure-Activity Relationship (SAR): Understanding the relationship between the compound's structure and its biological activity is crucial. Each substituent on the molecular framework can influence interaction at biological targets, making studies of SAR vital in drug design.
  • Applications Beyond Medicine: Beyond pharmaceuticals, compounds with similar structures are sometimes used in agrochemicals, dyes, or as intermediates in chemical syntheses, showcasing their versatility in various fields.
  • Research Potential: Scientists are continuously exploring this compound to uncover its properties and potential applications, thus making it an exciting area for future investigations.

In conclusion, ethyl 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]acetate exemplifies the intricate relationship between molecular structure and functionality in organic chemistry. As research progresses, we may discover even more about its capabilities and applications.

Synonyms
29484-98-8
(alpha-Methyl-m-trifluoromethylphenethylamino)acetic acid ethyl ester
ACETIC ACID, (alpha-METHYL-m-TRIFLUOROMETHYLPHENETHYLAMINO)-, ETHYL ESTER
RefChem:316292
DTXSID90951996
ethyl N-{1-[3-(trifluoromethyl)phenyl]propan-2-yl}glycinate