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Ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate

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Identification
Molecular formula
C12H14N2O2S
CAS number
73899-85-1
IUPAC name
ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate
State
State

At room temperature, it is a solid.

Melting point (Celsius)
119.00
Melting point (Kelvin)
392.20
Boiling point (Celsius)
566.60
Boiling point (Kelvin)
839.80
General information
Molecular weight
264.32g/mol
Molar mass
264.3180g/mol
Density
1.3100g/cm3
Appearence

Ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate typically appears as a white to off-white powder or crystalline solid.

Comment on solubility

Solubility of Ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate

The solubility of ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate can be influenced by various factors associated with its molecular structure and the solvent used.

  • Polarity: The presence of both the benzimidazole ring and the ethyl acetate group suggests a balance between hydrophilic and hydrophobic properties, which may result in moderate solubility in polar solvents.
  • Solvent Interaction: This compound may exhibit greater solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), but might be less soluble in water due to its aromatic components.
  • Temperature Influence: As with many organic compounds, an increase in temperature may enhance solubility, allowing for better dissolution in suitable solvents.

In summary, the solubility of ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate is expected to be variable, potentially soluble in organic environments while exhibiting limitations in aqueous conditions. As with all compounds, conducting specific solubility tests in different solvents will provide the most accurate understanding of its solubility profile.

Interesting facts

Interesting Facts about Ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate

Ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate is a fascinating compound that integrates the structural features of benzimidazole and thioether functionalities. This combination imparts unique properties and potential applications in various fields, notably in medicinal chemistry.

Key Features:

  • Benzimidazole Backbone: Benzimidazole is known for its significant pharmacological activities, including antibacterial, antiviral, and anticancer properties. The presence of this moiety in the compound enhances its potential as a therapeutic agent.
  • Thioether Linkage: The sulfanyl group contributes to the compound's reactivity and may influence its interaction with biological targets, offering avenues for drug design.
  • Versatile Synthesis: The synthetic routes leading to this compound can be varied, often allowing for customization and modification, making it valuable in organic synthesis.

This compound illustrates the beauty of synthetic chemistry, where simple structural changes can lead to vastly different biological activities. In a constantly evolving landscape of drug discovery, compounds like ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate stand out as promising leads for further research.

Moreover, as researchers continue to explore the potential of benzimidazole derivatives, this compound may play a pivotal role in developing new therapies. According to a recent study, "the derivatives of benzimidazole have shown great promise in clinical applications, and compounds such as ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate could be key to advancing our understanding of this class of compounds."

In summary, this compound’s unique structural attributes combined with its biological potential make it an exciting subject for both theoretical study and practical application in drug development.

Synonyms
ethyl 2-(1H-1,3-benzodiazol-2-ylsulfanyl)acetate
Ethyl 2-(1H-benzimidazol-2-ylthio)acetate
963-751-1
5429-62-9
ethyl 2-(1H-benzimidazol-2-ylsulfanyl)acetate
ACETIC ACID, 2-BENZIMIDAZOLYLTHIO-, ETHYL ESTER
Ethyl=(1H-benzimidazol-2-ylthio)acetate
2-Benzimidazolylthioacetic acid ethyl ester
2-(Carboethoxymethylmercapto)benzimidazole
Acetic acid, (1H-benzimidazol-2-ylthio)-, ethyl ester
Ethyl 2-((1H-benzo[d]imidazol-2-yl)thio)acetate
NSC-14189
ethyl (1H-benzimidazol-2-ylsulfanyl)acetate
ETHYL (1H-BENZIMIDAZOL-2-YLTHIO)ACETATE
NSC 14189
BRN 0203676
MFCD00121550
Maybridge1_003523
ChemDiv1_000592
ethyl 2-(1H-benzo[d]imidazol-2-ylthio)acetate
5-23-11-00273 (Beilstein Handbook Reference)
SCHEMBL944312
U6FUL7Q999
(1H-Benzoimidazol-2-ylsulfanyl)-acetic acid ethyl ester
(1H-Benzoimidazol-2-ylsulfanyl)acetic acid ethyl ester
HMS588K20
DTXSID00202648
ALBB-037423
FAA42962
NSC14189
BBL037999
STK346869
AKOS000313813
CCG-103882
2-[(Carboethoxymethyl)mercapto]benzimidazole
CS-0222430
EU-0084355
EN300-111102
G22975
Ethyl2-((1H-benzo[d]imidazol-2-yl)thio)acetate
SR-01000399375
SR-01000399375-1
Z54065866
(1H-benzoimidazol-2-ylsulfanyl) acetic acid ethyl ester
Acetic acid, 2-(1H-1,3-benzimidazol-2-ylthio)-, ethyl ester