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Ethyl 2-[(2-fluoroacetyl)amino]acetate

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Identification
Molecular formula
C6H10FNO3
CAS number
606-32-0
IUPAC name
ethyl 2-[(2-fluoroacetyl)amino]acetate
State
State

At room temperature, ethyl 2-[(2-fluoroacetyl)amino]acetate is in a liquid state. It is commonly handled as a liquid due to its relatively low melting point.

Melting point (Celsius)
-9.00
Melting point (Kelvin)
264.15
Boiling point (Celsius)
207.00
Boiling point (Kelvin)
480.15
General information
Molecular weight
179.16g/mol
Molar mass
179.1580g/mol
Density
1.2330g/cm3
Appearence

Ethyl 2-[(2-fluoroacetyl)amino]acetate is typically a colorless liquid. Its appearance may vary slightly with impurities or under different conditions, but it generally retains a clear liquid form at room temperature.

Comment on solubility

Solubility of Ethyl 2-[(2-fluoroacetyl)amino]acetate

When considering the solubility of ethyl 2-[(2-fluoroacetyl)amino]acetate, also known by its chemical formula C5H8FNO2, several factors come into play. This compound's solubility characteristics can be influenced by its functional groups and molecular interactions.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups, such as the amine and ester groups, generally enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amine and carbonyl groups in the structure can significantly contribute to its solubility in various solvents.
  • Temperature: Solubility may increase with temperature. Conducting experiments at different temperatures can provide insights into its solubility profile.
  • pH Sensitivity: The solubility of this compound may vary with the pH of the solution, particularly if any ionizable groups are present.

In summary, ethyl 2-[(2-fluoroacetyl)amino]acetate exhibits a unique solubility profile that is largely determined by its chemical structure and environmental conditions. As wit many compounds, the precise solubility should be determined through empirical testing under given conditions.

Interesting facts

Interesting Facts about Ethyl 2-[(2-fluoroacetyl)amino]acetate

Ethyl 2-[(2-fluoroacetyl)amino]acetate is a fascinating compound with a variety of applications and intriguing properties that make it noteworthy in the field of chemistry. Here are some captivating aspects to consider:

  • Pharmaceutical Insights: This compound belongs to a class of molecules that exhibit potential pharmacological activity. It is often explored for its ability to act as an intermediate in the synthesis of various bioactive compounds, which can lead to the development of new pharmaceuticals.
  • Fluorine Substitution: The presence of a fluorine atom in its structure significantly influences its reactivity and biological properties. Fluorinated compounds are commonly known for their enhanced metabolic stability and lipophilicity, making them valuable in medicinal chemistry.
  • Chirality Considerations: The existence of chiral centers within the compound opens the door to interesting stereochemical discussions. Different stereoisomers may exhibit varied biological activities, which highlights the importance of chirality in drug development.
  • Applications in Organic Synthesis: Ethyl 2-[(2-fluoroacetyl)amino]acetate can serve as a versatile building block in organic synthesis, allowing chemists to create a wide range of derivatives that may have unique properties or uses, particularly in material science and agrochemicals.
  • Research Opportunities: Due to its interesting structural features, it offers numerous research opportunities. Scientists are continually examining species like this for their reactivity patterns and potential uses in innovative chemical processes.

As a student of chemistry or a professional chemist, appreciating compounds like ethyl 2-[(2-fluoroacetyl)amino]acetate not only broadens your knowledge base but also enhances your understanding of how subtle changes in molecular structures can lead to vastly different properties and applications. Engaging with such compounds is crucial in advancing the frontiers of chemical science!

Synonyms
Ethyl fluoroacetamidoacetate
372-74-7
Fluoroacetamidoacetic acid, ethyl ester
ACETIC ACID, (2-FLUOROACETAMIDO)-, ETHYL ESTER
BRN 1775100
DTXSID60190693
3-04-00-01151 (Beilstein Handbook Reference)
DTXCID00113184