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Metronidazole acetate

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Identification
Molecular formula
C8H11N3O4
CAS number
102453-66-7
IUPAC name
ethyl 2-(2-methyl-5-nitro-imidazol-1-yl)acetate
State
State

At room temperature, Metronidazole acetate is typically in a solid crystalline state.

Melting point (Celsius)
110.50
Melting point (Kelvin)
383.65
Boiling point (Celsius)
408.90
Boiling point (Kelvin)
682.05
General information
Molecular weight
229.20g/mol
Molar mass
229.2020g/mol
Density
1.4600g/cm3
Appearence

Metronidazole acetate typically appears as a crystalline solid. It can vary from a colorless to a white or off-white powder and may have a characteristic odor depending on the presence of impurities or specific crystalline forms.

Comment on solubility

Solubility of Ethyl 2-(2-Methyl-5-Nitro-Imidazol-1-yl)Acetate

Ethyl 2-(2-methyl-5-nitro-imidazol-1-yl)acetate is known for its interesting solubility characteristics. Understanding its solubility can help in various applications ranging from drug formulation to chemical synthesis.

Factors Affecting Solubility

The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of polar groups, such as the nitro group, can enhance solubility in polar solvents like water.
  • Temperature: Increasing temperature often increases solubility, allowing more molecules to dissolve in a solvent.
  • Solvent Type: Ethyl 2-(2-methyl-5-nitro-imidazol-1-yl)acetate may exhibit varying solubility in different solvents. For instance, it is more soluble in organic solvents compared to aqueous solutions.

Common Solvents

In laboratory practices, this compound is generally found to be:

  • Moderately soluble in ethanol and methanol.
  • Less soluble in water due to its organic structure.

When considering the usage of this compound, it is essential to take into account the solubility profile as it can significantly impact both theoretical studies and practical applications. As noted, "solubility is not just a property, but a critical determinant of compound functionality."

Interesting facts

Interesting Facts about Ethyl 2-(2-methyl-5-nitro-imidazol-1-yl)acetate

Ethyl 2-(2-methyl-5-nitro-imidazol-1-yl)acetate is a fascinating compound that has garnered attention in various fields of chemistry. Here are some intriguing aspects of this compound:

  • Medical Applications: This compound is noted for its potential applications in medicinal chemistry. The imidazole ring, a crucial part of its structure, is often found in numerous pharmaceutical agents, particularly those that have antifungal and antibacterial properties.
  • Role in Synthesis: The nitro group present in this compound is particularly interesting for organic synthesis, as it can be converted into various functional groups through reduction reactions, leading to a variety of useful derivatives.
  • Biological Significance: The compound may also play a role in the research of cancer treatments. Imidazole derivatives have been studied for their ability to inhibit certain enzymes associated with tumor growth, making this compound a candidate for further exploration.
  • Analytical Chemistry: Due to its unique structure, this compound can serve as a target for chromatographic analysis, which is essential in both academic and industrial laboratories for understanding compound purity and composition.
  • Versatile Reactivity: The presence of both ester and nitro functionalities in the molecule allows for diverse reactivity, making it a valuable intermediate in the synthesis of other complex organic molecules.

In summary, Ethyl 2-(2-methyl-5-nitro-imidazol-1-yl)acetate showcases the intriguing intersection of organic chemistry and medicinal research. Its unique properties and potential applications make it a compound of significant interest for future studies and innovations in the field.

Synonyms
1016-40-6
ethyl 2-(2-methyl-5-nitroimidazol-1-yl)acetate
IMIDAZOLE-1-ACETIC ACID, 2-METHYL-5-NITRO-, ETHYL ESTER
2-Methyl-5-nitro-1H-imidazole-1-acetic acid ethyl ester
2-Methyl-5-nitroimidazole-1-acetic acid, ethyl ester
ethyl 2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetate
BRN 0617040
Oprea1_507904
DTXSID10144040
CKGGIKOPFUMXET-UHFFFAOYSA-N
1H-Imidazole-1-acetic acid, 2-methyl-5-nitro-, ethyl ester
DA-48368
Ethyl 2-methyl-5-nitro-1H-imidazole-1-acetate
Ethyl (2-methyl-5-nitro-1H-imidazol-1-yl)acetate
Ethyl (2-methyl-5-nitro-1H-imidazol-1-yl)acetate #