Skip to main content

Ethyl 2-(2-nitroanilino)acetate

ADVERTISEMENT
Identification
Molecular formula
C10H12N2O4
CAS number
22026-27-1
IUPAC name
ethyl 2-(2-nitroanilino)acetate
State
State

At room temperature, ethyl 2-(2-nitroanilino)acetate is typically found in a solid state.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.20
Boiling point (Celsius)
396.50
Boiling point (Kelvin)
669.60
General information
Molecular weight
238.23g/mol
Molar mass
238.2260g/mol
Density
1.3150g/cm3
Appearence

Ethyl 2-(2-nitroanilino)acetate typically appears as a yellow to orange crystalline solid, depending on the purity and the exact conditions of crystallization.

Comment on solubility

Solubility of Ethyl 2-(2-nitroanilino)acetate

Ethyl 2-(2-nitroanilino)acetate exhibits interesting solubility properties that can influence its implementation in various applications. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is typically soluble in organic solvents such as ethanol, acetone, and chloroform. These solvents can effectively solvate the compound due to their polar characteristics.
  • Water Solubility: Ethyl 2-(2-nitroanilino)acetate shows low solubility in water, which is attributed to its hydrophobic ethyl group and bulky aromatic structure.
  • Influencing Factors: pH and temperature can also play significant roles in its solubility. For instance, changing the pH of the solvent may result in ionization of functional groups, thereby affecting solubility.
  • Practical Implications: The solubility characteristics highlight its potential for use in organic synthesis and organic laboratory settings, where the choice of solvent is crucial for reactivity and product formation.

In conclusion, the solubility behavior of ethyl 2-(2-nitroanilino)acetate is multifaceted and influenced by various factors, which needs to be considered in practical applications and research scenarios.

Interesting facts

Interesting Facts about Ethyl 2-(2-Nitroanilino)acetate

Ethyl 2-(2-nitroanilino)acetate, often celebrated in the realm of organic chemistry, stands out for its intriguing structure and potential applications. This compound is an important derivative of amino acids, which are the building blocks of proteins, and showcases the beauty of functional group transformations. Here are some notable aspects:

  • Versatile Intermediate: This compound serves as a crucial intermediate in the synthesis of various pharmaceuticals, making it a valuable asset in medicinal chemistry.
  • Substituent Influence: The nitro group in the molecule significantly influences its chemical reactivity and properties, providing unique pathways for chemical modifications.
  • Analytical Applications: Ethyl 2-(2-nitroanilino)acetate is often utilized in studies involving spectrophotometry, where its distinct absorption characteristics are exploited to analyze various compounds.
  • Biological Relevance: Some derivatives of this compound have shown biological activities that could be beneficial in drug development, particularly in targeting certain diseases.
  • Research Interest: The compound has been the focus of numerous studies aimed at understanding its mechanisms of action and potential therapeutic uses in various fields, including cancer research.

As scientists delve deeper into the properties of ethyl 2-(2-nitroanilino)acetate, the compound continues to reveal its complexities and promises new advancements in chemical synthesis and medicinal formulations. Its role in bridging the gap between organic synthesis and practical application is a testament to the interconnected nature of chemistry.

Synonyms
Ethyl 2-[(2-nitrophenyl)amino]acetate
5428-05-7
Ethyl 2-((2-nitrophenyl)amino)acetate
Glycine, N-(2-nitrophenyl)-, ethyl ester
GLYCINE, N-(o-NITROPHENYL)-, ETHYL ESTER
Ethyl N-(o-nitrophenyl)glycinate
ethyl 2-(2-nitroanilino)acetate
NSC12797
N-(o-Nitrophenyl)glycine ethyl ester
NSC 12797
BRN 2740408
DTXSID50202633
NSC-12797
AKOS008967476
Ethyl2-((2-nitrophenyl)amino)acetate
SB77303
BS-32543
CS-0209782
EN300-7360836
F1911-3529