Skip to main content

Ethyl 2-(4-chloro-2-methylpyrimidin-5-yl)acetate

ADVERTISEMENT
Identification
Molecular formula
C9H11ClN2O2
CAS number
73096-30-5
IUPAC name
ethyl 2-(4-chloro-2-methyl-pyrimidin-5-yl)acetate
State
State

This compound is typically a liquid at room temperature and pressure.

Melting point (Celsius)
-1.50
Melting point (Kelvin)
271.65
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.00
General information
Molecular weight
229.65g/mol
Molar mass
229.6500g/mol
Density
1.2060g/cm3
Appearence

Ethyl 2-(4-chloro-2-methylpyrimidin-5-yl)acetate appears as a colorless to pale yellow liquid at room temperature. It may have a characteristic odor associated with organic esters.

Comment on solubility

Solubility of Ethyl 2-(4-chloro-2-methyl-pyrimidin-5-yl)acetate

Ethyl 2-(4-chloro-2-methyl-pyrimidin-5-yl)acetate is a compound with unique solubility properties that make it particularly interesting in various applications. This ester's solubility can primarily be influenced by the following factors:

  • Polarity: The presence of the pyrimidine ring contributes to its overall polarity, which can enhance its solubility in polar solvents.
  • Hydrophobic Characteristics: The ethyl group provides a hydrophobic character, allowing it to dissolve well in organic solvents such as ethanol, acetone, and chloroform.
  • Solvent Interaction: When examined in aqueous environments, the compound may demonstrate limited solubility due to the hydrophobic properties dominating over the polar interactions.

In summary, while ethyl 2-(4-chloro-2-methyl-pyrimidin-5-yl)acetate is sparingly soluble in water, it shows good solubility in a variety of organic solvents, making it versatile for use in organic synthesis and other chemical applications. Understanding this solubility behavior is essential for optimizing its use in laboratory settings.

Interesting facts

Interesting Facts About Ethyl 2-(4-Chloro-2-methyl-pyrimidin-5-yl)acetate

Ethyl 2-(4-chloro-2-methyl-pyrimidin-5-yl)acetate is a fascinating compound that belongs to the class of ethyl esters, which are known for their applications in various fields such as pharmaceuticals and agrochemicals. Here are some intriguing aspects of this compound:

  • Pyrimidine Derivative: This compound features a pyrimidine ring, a six-membered heterocycle that is integral to many biological and chemical processes. Pyrimidines are common in nucleic acids and play a crucial role in molecular biology.
  • Substituent Diversity: The presence of the 4-chloro-2-methyl substituent adds unique properties to the molecule, influencing its reactivity and interaction with biological systems. Chlorinated compounds, in particular, are widely studied for their potential as herbicides and pharmaceuticals.
  • Pharmaceutical Potential: Compounds similar to ethyl 2-(4-chloro-2-methyl-pyrimidin-5-yl)acetate have been investigated for their ability to act as inhibitors of various enzymes, which could lead to the development of new drugs targeting diseases related to cell division and metabolism.
  • Applications in Agrochemicals: Interestingly, pyrimidine derivatives are often utilized in the design of new agrochemicals. This compound’s structure suggests it could have herbicidal or fungicidal properties, making it a candidate for research in agricultural applications.
  • Synthesis Insights: Understanding how to synthesize this compound can provide valuable insights into organic chemistry techniques, such as esterification and nucleophilic substitution reactions, which are fundamental in creating complex organic molecules.

This compound’s unique structure and the functions of its individual components make it a subject of interest for both chemists and pharmaceuticals researchers. It serves as a reminder of the intricate relationship between chemical structure and biological activity.

Synonyms
HSDB 2677
(6-CHLORO-2-METHYL-5-PYRIMIDYL)ACETIC ACID, ETHYL ESTER
UNII-2S581R662D
ethyl (6-chloro-2-methyl-5-pyrimidyl)acetate
DTXSID10162143
DTXCID6084634
5Pyrimidineacetic acid, 4chloro2methyl, ethyl ester
Acetic acid, (6chloro2methyl5pyrimidyl), ethyl ester
14273-76-8
ethyl 2-(4-chloro-2-methylpyrimidin-5-yl)acetate
2S581R662D
5-Pyrimidineacetic acid, 4-chloro-2-methyl-, ethyl ester
Acetic acid, (6-chloro-2-methyl-5-pyrimidyl)-, ethyl ester
SCHEMBL8880069
UXHQKBUDSNPVJV-UHFFFAOYSA-N
ethyl2-(4-chloro-2-methylpyrimidin-5-yl)acetate
Q27255533
Ethyl alpha-(2-methyl-4-chloro-5-pyrimidinyl)-acetate