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Ethyl 2-(4-nitroanilino)acetate

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Identification
Molecular formula
C10H12N2O4
CAS number
607-97-2
IUPAC name
ethyl 2-(4-nitroanilino)acetate
State
State
At room temperature, ethyl 2-(4-nitroanilino)acetate is in a solid state. The compound typically maintains its stability under standard conditions, making it suitable for various chemical applications that require a stable solid form.
Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
355.50
Boiling point (Kelvin)
628.65
General information
Molecular weight
238.23g/mol
Molar mass
238.2260g/mol
Density
1.3000g/cm3
Appearence
Ethyl 2-(4-nitroanilino)acetate typically appears as a yellow crystalline powder. It is important to note that color and texture may vary depending on the purity and specific preparation methods of the compound.
Comment on solubility

Solubility of Ethyl 2-(4-nitroanilino)acetate

Ethyl 2-(4-nitroanilino)acetate, identified by its molecular formula, shows interesting solubility characteristics that merit discussion. Generally, the solubility of organic compounds like this one is influenced by several factors such as:

  • Polarity: The presence of both ethyl and nitro groups introduces varying degrees of polarity, affecting solubility in different solvents.
  • Temperature: Solubility tends to increase with temperature; thus, a higher thermal environment may improve its dissolving capacity.
  • pH levels: Being an amine derivative, the solubility can fluctuate with changes in pH, altering its protonation state.

In general, this compound is expected to be soluble in organic solvents such as ethanol and methanol, while showing limited solubility in water due to its organic nature. This is common for esters and amines, where the balance of hydrophobic (water-repelling) and hydrophilic (water-attracting) characteristics plays a crucial role. It is important to note that:

  • The nitro group tends to enhance solubility in polar solvents.
  • The ethyl acetate portion can aid in dissolving the compound in less polar solutions.

As such, one may say, “The solubility of ethyl 2-(4-nitroanilino)acetate is a captivating interplay between its molecular structure and the solvent environment.” Understanding these aspects is crucial for applications ranging from chemical synthesis to formulation in pharmaceuticals.

Interesting facts

Interesting Facts About Ethyl 2-(4-nitroanilino)acetate

Ethyl 2-(4-nitroanilino)acetate is a fascinating compound that has garnered attention in both organic chemistry and medicinal research fields. Here are some key points that highlight its significance:

  • Synthetic Intermediates: This compound serves as an essential intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its structure provides avenues for further chemical transformations, demonstrating the versatility of nitroaniline derivatives.
  • Pharmacological Potential: Compounds similar to ethyl 2-(4-nitroanilino)acetate have shown promising biological activity. Research suggests that nitroaniline derivatives may possess antibacterial, antiviral, and even anticancer properties, presenting opportunities for new drug development.
  • Reaction Mechanisms: It can participate in various organic reactions, such as nucleophilic substitutions and electrophilic aromatic substitutions. Understanding these mechanisms is crucial for chemists aiming to manipulate its structure for desired outcomes.
  • Colorimetric Applications: Due to the presence of the nitro group, this compound can be useful in colorimetric analysis, where it may serve as a reagent for the qualitative detection of certain other compounds in a mixture.
  • Environmental Impact: The study of nitro compounds is also pertinent in environmental chemistry, where their potential as pollutants may require careful monitoring and research into degradation pathways.

Overall, ethyl 2-(4-nitroanilino)acetate showcases the intersection of organic chemistry with practical applications, paving the way for new discoveries and innovations in both medicinal and environmental sciences. As one researcher noted, "The journey of a compound from the lab to potential life-saving applications is a beautiful testament to the power of chemistry."

Synonyms
3589-59-1
ethyl 2-(4-nitroanilino)acetate
GLYCINE, N-(p-NITROPHENYL)-, ETHYL ESTER
N-(4-Nitrophenyl)glycine ethyl ester
BRN 2735598
Ethyl N-(p-nitrophenyl)glycinate
N-(p-Nitrophenyl)glycine ethyl ester
ethyl (4-nitroanilino)acetate
DTXSID80189448
ZJSORJPYCPRKMN-UHFFFAOYSA-N
AKOS009135728