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Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate

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Identification
Molecular formula
C13H17NO4
CAS number
3329-79-5
IUPAC name
ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate
State
State

At room temperature, Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate is a solid.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
411.00
Boiling point (Kelvin)
684.15
General information
Molecular weight
279.31g/mol
Molar mass
279.3060g/mol
Density
1.2000g/cm3
Appearence

Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate is typically a white crystalline solid. It can appear as a fine powder and is generally odorless.

Comment on solubility

Solubility of Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate

Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate, with the chemical formula C13H17NO4, exhibits interesting solubility characteristics that are essential for its applications in various fields, including pharmaceuticals and organic synthesis.

Key Points on Solubility:

  • Polarity: The presence of both an acetamido group and a hydroxyphenyl group contributes to the compound's polarity, which can enhance its solubility in polar solvents.
  • Solvent Compatibility: This compound tends to be more soluble in organic solvents, such as ethanol and dichloromethane, compared to water, making it suitable for various organic reactions.
  • Temperature Influence: Solubility may increase with temperature, which is a common behavior seen in many organic compounds, allowing for better dissolution under heated conditions.

In general, the solubility of ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate is influenced by its structural features, specifically the functional groups that dictate interactions with solvents. Such characteristics are crucial when considering its practical applications, as solubility can affect reactivity and biological activity.

Interesting facts

Interesting Facts About Ethyl 2-Acetamido-3-(4-Hydroxyphenyl)propanoate

Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate is a fascinating compound that showcases the intriguing relationships between chemical structure and biological activity. This compound is noteworthy for several reasons:

  • Pharmacological Potential: Compounds with the acetamido group often exhibit medicinal properties. Ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate may hold promise in the development of new therapeutic agents due to its structural similarities to known pharmaceuticals.
  • Phenolic Influence: The presence of the 4-hydroxyphenyl group not only enhances solubility properties but is also responsible for the compound's potential antioxidant activities, which can protect the body against oxidative stress.
  • Synthetic Versatility: This compound can act as a building block for synthesizing other complex molecules, demonstrating its versatility in organic synthesis. This feature makes it of particular interest to chemists working on new synthetic routes.
  • Structure-Activity Relationship (SAR): Studying the modifications of the ethyl acetamido structure enables scientists to understand the relationship between a molecule's structure and its biological activity, facilitating drug discovery processes.

As one delves deeper into the chemistry of this compound, one might ponder: "How can slight modifications to this compound alter its efficacy as a pharmaceutical?" This inquiry highlights the ever-evolving nature of chemical research, where the distinction between a compound's structure and its function is a pathway toward innovation.

Overall, ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate is a prime example of how a simple modification can lead to diverse functionalities and significant impacts in fields like medicinal chemistry and drug design.

Synonyms
ethyl N-acetyltyrosinate
ACETYL TYROSINE ETHYL ESTER
ethyl 2-acetamido-3-(4-hydroxyphenyl)propanoate
acetyltyrosine ethyl ester
Ethyl acetyltyrosine
Ethyl acetyltyrosinate
N-Acetyltyrosine ethyl ester
Acetyl-L-tyrosine ethyl ester
N-Acetyl-L-tyrosyl ethyl ester
30697-69-9
Ethyl (2S)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoate
NSC 64725
NSC 87506
Tyrosine, N-acetyl-, ethyl ester, L-
Spectrum_000396
Spectrum2_001345
Spectrum3_001394
Spectrum4_000107
Spectrum5_001342
Ac-Tyr-OEt * H2O
N-acetyl-l-tyr ethyl ester
NCIOpen2_003135
BSPBio_003008
CBDivE_014491
KBioGR_000434
KBioSS_000876
DivK1c_000250
SCHEMBL468858
SPECTRUM1500695
SPBio_001529
CHEMBL1354672
HMS500M12
KBio1_000250
KBio2_000876
KBio2_003444
KBio2_006012
KBio3_002228
SKAWDTAMLOJQNK-UHFFFAOYSA-
DTXSID90862437
CHEBI:110178
NINDS_000250
SKAWDTAMLOJQNK-UHFFFAOYSA-N
HMS1921E08
NSC64725
NSC87506
SYE-3008
CCG-39283
NSC-64725
NSC-87506
STK048746
AKOS000491736
AKOS016352351
IDI1_000250
NCGC00094836-01
NCGC00094836-02
NCGC00094836-03
Acetyl-L-Tyrosine Ethyl Ester Monohydrate
EN300-717785
ethyl2-acetamido-3-(4-hydroxyphenyl)propanoate
BRD-A55063801-001-02-6
Q27189558
Z57205547
2-acetamido-3-(4-hydroxyphenyl)propanoic acid ethyl ester
InChI=1/C13H17NO4/c1-3-18-13(17)12(14-9(2)15)8-10-4-6-11(16)7-5-10/h4-7,12,16H,3,8H2,1-2H3,(H,14,15)