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Glycine ethyl ester

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Identification
Molecular formula
C4H9NO2
CAS number
459-73-4
IUPAC name
ethyl 2-aminoacetate
State
State

At room temperature, Glycine ethyl ester is typically in a liquid state.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.00
Boiling point (Celsius)
167.00
Boiling point (Kelvin)
440.00
General information
Molecular weight
103.12g/mol
Molar mass
103.1190g/mol
Density
1.0729g/cm3
Appearence

Glycine ethyl ester typically appears as a colorless to pale yellow liquid. It has a characteristic ethereal odor.

Comment on solubility

Solubility of Ethyl 2-Aminoacetate

Ethyl 2-aminoacetate, also known as ethyl glycine ester, is a compound that exhibits interesting solubility properties. Its solubility can be influenced by several factors:

  • Polarity: Ethyl 2-aminoacetate is polar due to the presence of the amino group (-NH2) and the ester functional group. This polarity allows it to interact favorably with water, leading to a moderate degree of solubility.
  • Solvents: It is generally soluble in polar solvents such as water and alcohols, making it useful in various chemical applications. Its solubility in organic solvents like ethanol can enhance its versatility.
  • pH Dependence: The solubility of ethyl 2-aminoacetate can be significantly affected by the pH of the solution; at lower pH levels, the amino group can become protonated, which may increase solubility in an aqueous environment.

As a general guideline, one may find that:

  1. It dissolves well in water, especially with slight heating.
  2. It can form salts with acids, which generally increases solubility in aqueous solutions.

In conclusion, the solubility of ethyl 2-aminoacetate makes it an easily manipulable compound in laboratories, with the ability to dissolve in various solvent systems, thus broadening its utility in chemical synthesis and formulation.

Interesting facts

Interesting Facts About Ethyl 2-Aminoacetate

Ethyl 2-aminoacetate, also known as ethyl glycinate, is an intriguing compound that demonstrates a range of interesting properties and applications, particularly in the fields of organic chemistry and biochemistry.

Key Characteristics

  • Versatile Building Block: Ethyl 2-aminoacetate serves as a versatile building block in organic synthesis. Its ability to easily participate in various reactions allows chemists to construct a wide array of complex molecules.
  • Amine Reactivity: Being an amine, it can undergo reactions such as alkylation, acylation, and reductive amination, making it valuable for the development of pharmaceuticals and agrochemicals.
  • Applications in Medicine: This compound has shown potential in medicinal chemistry. It may serve as an intermediate in the synthesis of amino acid derivatives and other bioactive compounds.

Biological Relevance

In biological systems, amino acids and their derivatives play crucial roles:

  • Metabolic Pathways: Ethyl 2-aminoacetate can be incorporated into metabolic pathways, contributing to the synthesis of proteins and other essential biomolecules.
  • Potential as a Neuroprotective Agent: Research is ongoing to explore possible neuroprotective effects linked to similar amino acids, highlighting the compound's intriguing biological attributes.

Quote from the Field

A noted scientist once said, "Every small compound has a big role to play in the vast tapestry of chemistry." Ethyl 2-aminoacetate certainly embodies this notion, showcasing the interconnectedness of chemical compounds.

Conclusion

Ethyl 2-aminoacetate is more than just a simple compound; it is a significant player in chemical synthesis and biological processes. Its diverse reactivity and potential applications continue to make it an area of interest for researchers and chemists alike.

Synonyms
Ethyl glycinate
Ethyl 2-aminoacetate
Glycine ethyl ester
Ethyl aminoacetate
Ethyl glycine
(Ethoxycarbonyl)methylamine
Glicine, ethyl ester
EINECS 207-298-3
Aminoacetic acid, ethyl ester
DTXSID90196648
DTXCID30119139
207-298-3
ntnzteqnfhnybc-uhfffaoysa-n
459-73-4
Glycine, ethyl ester
H-Gly-OEt
ETHYL 2-AMINO ACETATE
AMINO-ACETIC ACID ETHYL ESTER
glycine ethyl
glycine ethylester
glycine-ethyl ester
GEE
MFCD00799972
ethyl 2-amino-acetate
ethyl-2-amino-acetate
H-Gly-OEt, salt HCl
H-Gly-OC2H5
4F4DGF5APZ
SCHEMBL682
aminoacetic acid ethyl ester
CHEMBL2448938
STK367828
AKOS000247802
BP-31276
BS-12707
PD196065
SY021455
DB-007471
HY-148666
CS-0636597
NS00008197
EN300-49517
AB00514793-02
Q27460686