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Ethyl 2-bromoisobutyrate

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Identification
Molecular formula
C6H11BrO2
CAS number
600-00-0
IUPAC name
ethyl 2-bromo-2-methyl-propanoate
State
State

At room temperature, ethyl 2-bromoisobutyrate is in a liquid state. It is typically handled as a liquid and stored in well-sealed containers to prevent moisture absorption and decomposition.

Melting point (Celsius)
-45.00
Melting point (Kelvin)
228.15
Boiling point (Celsius)
149.00
Boiling point (Kelvin)
422.15
General information
Molecular weight
181.06g/mol
Molar mass
181.0620g/mol
Density
1.3410g/cm3
Appearence

Ethyl 2-bromoisobutyrate is a colorless to light yellow liquid. It has a characteristic ester-like odor and is known for its oily consistency. The compound may become slightly colored upon exposure to air and light.

Comment on solubility

Solubility of Ethyl 2-bromo-2-methyl-propanoate

Ethyl 2-bromo-2-methyl-propanoate, with the chemical formula C5H9BrO2, exhibits some interesting solubility characteristics due to its structure. Understanding the solubility of this compound can be crucial for various chemical processes. Here are some key points to consider:

  • Polarity: The presence of the bromine atom and the ester functional group contributes to its polar nature. Generally, polar compounds tend to dissolve well in polar solvents.
  • Solvents: Ethyl 2-bromo-2-methyl-propanoate is more soluble in organic solvents such as ethanol and acetone compared to water, due to the lack of strong hydrogen bonding with water molecules.
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature. Elevated temperatures may enhance its solubility in organic solvents.
  • Applications: Its solubility characteristics make ethyl 2-bromo-2-methyl-propanoate useful in synthesis and extraction processes.

In summary, the solubility of ethyl 2-bromo-2-methyl-propanoate is influenced by its molecular structure, making it more compatible with organic solvents rather than aqueous solutions. This can be a crucial factor in its application within the chemical industry.

Interesting facts

Interesting Facts About Ethyl 2-Bromo-2-Methylpropanoate

Ethyl 2-bromo-2-methylpropanoate is a fascinating compound with a range of applications in the field of organic chemistry. Here are some intriguing aspects that highlight its significance:

  • Synthetic Versatility: This compound serves as an important building block in the synthesis of various pharmaceuticals and agrochemicals, showcasing its utility in medicinal and agricultural chemistry.
  • Reactivity: The presence of the bromine atom in its structure imparts unique reactivity, making it an ideal candidate for substitution reactions. This characteristic enables chemists to manipulate and generate diverse organic compounds efficiently.
  • Stereochemistry: Being a chiral compound, ethyl 2-bromo-2-methylpropanoate can exist in different stereoisomeric forms. The configuration around the chiral center can significantly influence the biological activity and selectivity of its derivatives.
  • Applications in Laboratory: This compound is frequently used in laboratories for research purposes, particularly in studying reaction mechanisms and evaluating the effects of different functional groups in organic transformations.
  • Safety Considerations: While working with ethyl 2-bromo-2-methylpropanoate, safety precautions are vital due to the toxic nature of brominated compounds. Proper handling, including the use of personal protective equipment, is essential to ensure safe laboratory practices.

In summary, ethyl 2-bromo-2-methylpropanoate is not just a simple ester; it is a **versatile compound** that plays a critical role in various chemical transformations and applications. As researchers continue to explore its potential, the compound opens doors to innovative discoveries in both academic and industrial settings.

Synonyms
Ethyl 2-bromoisobutyrate
600-00-0
Ethyl 2-bromo-2-methylpropionate
6-Hydroxydopamine bromide
NSC 9465
2-Bromo-2-methylpropanoic acid, ethyl ester
NSC 402034
alpha-Bromoisobutyric acid, ethyl ester
Propanoic acid, 2-bromo-2-methyl-, ethyl ester
CCRIS 6546
EINECS 209-980-6
Propionic acid, 2-bromo-2-methyl-, ethyl ester
Ethyl alpha-bromo-alpha-methylpropionate
DTXSID4060523
EC 209-980-6
Ethyl alphabromoisobutyrate
Ethyl 2bromo2methylpropanoate
Ethyl 2bromo2methylpropionate
DTXCID6042739
2Bromoisobutyric acid ethyl ester
Ethyl alphabromoalphamethylpropionate
alphaBromoisobutyric acid, ethyl ester
2Bromo2methylpropanoic acid, ethyl ester
Propanoic acid, 2bromo2methyl, ethyl ester
Propionic acid, 2bromo2methyl, ethyl ester
209-980-6
Ethyl 2-bromo-2-methylpropanoate
ethyl-2-bromoisobutyrate
ETHYL ALPHA-BROMOISOBUTYRATE
Ethyl .alpha.-bromoisobutyrate
ethyl-2-bromo-isobutyrate
2-bromo-2-methylpropanoic acid ethyl ester
2-Bromoisobutyric Acid Ethyl Ester
MFCD00000123
.alpha.-Bromoisobutyric acid, ethyl ester
Ethyl .alpha.-bromo-.alpha.-methylpropionate
Propanoic acid, bromo-2-methyl-, ethyl ester
Ethyl |A-bromoisobutyrate
ethyl 2-bromo-2-methyl-propanoate
ethyl bromoisobutyrate
ethyl bromo-isobutyrate
Ethyl A-bromoisobutyrate
ethyl bromodimethylacetate
ethyl dimethylbromoacetate
ethyl 2-bromo-isobutyrate
ethylalpha-bromoisobutyrate
ethyl-alpha-bromoisobutyrate
SCHEMBL36821
Ethyl alpha -bromoisobutyrate
2-bromoisobutyrate ethyl ester
ethyl 2-bromo-2-methylpropanate
ethyl-2-bromo-2-methylpropanate
IOLQWGVDEFWYNP-UHFFFAOYSA-
2-Bromoisobutyricacid ethyl ester
ethyl 2-bromo-2methyl-propionate
ethyl-2-bromo-2-methylpropanoate
ethyl-2-bromo-2-methylpropionate
NSC9465
ethyl 2-bromo-2-methylproprionate
ethyl 2-bromo-2-methyl-propionate
ethyl 2-bromo-2,2-dimethylacetate
Ethyl alpha-bromoisobutyrate, 98%
BCP24420
NSC-9465
NSC402034
ethyl 2-bromanyl-2-methyl-propanoate
AKOS009157529
alpha-bromo-isobutyric acid ethyl ester
NSC-402034
2-bromo-2-methylpropanoic acid ethylester
BS-22382
2-bromo-2-methyl-propanoic acid ethylester
2-bromo-2-methylpropionic acid ethyl ester
DB-053510
2-bromo-2-methyl-propanoic acid ethyl ester
2-bromo-2-methyl-propionic acid ethyl ester
B0606
NS00003907
2-bromo-2-methyl-propionic acid, ethyl ester
EN300-51259
D87241
A832565
Ethyl alpha-bromoisobutyrate, purum, >=97.0% (GC)
F2190-0281
InChI=1/C6H11BrO2/c1-4-9-5(8)6(2,3)7/h4H2,1-3H3