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Ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate

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Identification
Molecular formula
C15H22N3O6PS
CAS number
123456-78-9
IUPAC name
ethyl 2-diethoxyphosphinothioyloxy-5-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylate
State
State

At room temperature, Ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate is a solid.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
510.00
Boiling point (Kelvin)
783.15
General information
Molecular weight
385.40g/mol
Molar mass
385.4000g/mol
Density
1.2500g/cm3
Appearence

Ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate appears as a yellow crystalline solid. Its crystalline form reflects light exhibiting a shiny luster.

Comment on solubility

Solubility of Ethyl 2-diethoxyphosphinothioyloxy-5-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylate

The solubility of ethyl 2-diethoxyphosphinothioyloxy-5-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylate can be described through several key features:

  • Solvent Dependence: This compound is often more soluble in organic solvents such as ethanol and acetone, rather than in polar solvents like water.
  • Functional Groups: The presence of diethoxy and carboxylate groups suggests potential for moderate solubility in polar organic solvents, while the phosphinothioyl group may also influence solvation.
  • Temperature Influence: Generally, an increase in temperature may enhance the solubility of this compound in organic solvents, allowing for greater molecular mobility.
  • pH Sensitivity: Because of its carboxylate moiety, the solubility may vary with pH, particularly showing increased solubility at higher pH levels.

In summary, while ethyl 2-diethoxyphosphinothioyloxy-5-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylate exhibits **selective solubility**, notably in organic media, its behavior can be markedly influenced by the surrounding conditions such as temperature and pH. Such characteristics underline the importance of considering solvent choice in practical applications.

Interesting facts

Interesting Facts about Ethyl 2-Diethoxyphosphinothioyloxy-5-methyl-Pyrazolo[1,5-a]Pyrimidine-6-Carboxylate

Ethyl 2-Diethoxyphosphinothioyloxy-5-methyl-Pyrazolo[1,5-a]Pyrimidine-6-Carboxylate is a fascinating compound that showcases the intricate world of organic and pharmaceutical chemistry. Here are some intriguing aspects of this compound:

  • Versatile Synthetic Pathways: The synthesis of this compound typically involves multi-step reactions, allowing for the exploration of various reaction conditions and methodologies. This makes it an exciting target for synthetic chemists looking to advance their skills.
  • Biological Significance: Compounds like this one often demonstrate remarkable biological activity, particularly in medicinal chemistry. Many pyrazolone derivatives have been linked to anti-inflammatory, analgesic, and antifungal properties. Understanding its pharmacological potential can lead to the development of new therapeutics.
  • Structural Complexity: The unique pyrazolo-pyrimidine backbone of this compound lends itself to interesting interactions with biological systems. Its design incorporates various functional groups that can influence its reactivity and biological activity.
  • Research Applications: Ethyl 2-Diethoxyphosphinothioyloxy-5-methyl-Pyrazolo[1,5-a]Pyrimidine-6-Carboxylate is a valuable subject for research in fields such as agrochemistry and materials science, where it could play a role in developing new pesticides or functionalized materials.
  • Chemical Behavior: Being a phosphinothioate, it has unique reactivity patterns that can be explored in various chemical reactions, including nucleophilic substitutions or coupling reactions, which are essential in organic synthesis.

As you delve into the study of this compound, remember that it embodies the beautiful complexity of chemistry, where molecular structure and function intertwine to create substances that can have significant impacts in various fields.

Synonyms
PYRAZOPHOS
13457-18-6
Curamil
Afugan
BEG0A8I17D
Ethyl 2-((diethoxyphosphinothioyl)oxy)-5-methylpyrazolo(1,5-a)pyrimidine-6-carboxylate
DTXSID7042352
CHEBI:81942
NSC-232671
DTXCID5022352
HOE-2873
O,O-Diethyl O-(5-methyl-6-(ethoxycarbonyl)-pyrazolo-(1,5-a)-pyrimid-2-yl)-thionophosphate
O-6-Ethoxycarbonyl-5-methylpyrazolo(1,5-a)pyrimidin-2-yl O,O-diethyl phosphorothioate
Ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
O-6-ethoxycarbonyl-5-methylpyrazolo[1,5-a]pyrimidin-2-yl O,O-diethyl phosphorothioate
236-656-1
Missile
Hoechst 2873
HOE 2873
NSC 232671
ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
O,O-Diethyl-O-(5-methyl-6-ethoxy-carbonyl-pyrazolo(1.5-a)pyrimid-2-yl)-thionophosphate
Pyrazophos 10 microg/mL in Isooctane
Pyrazolo(1,5-a)pyrimidine-6-carboxylic acid, 2-((diethoxyphosphinothioyl)oxy)-5-methyl-, ethyl ester
Phosphorothioic acid, O,O-diethyl ester, O-ester with (6-ethoxycarbonyl-5-methyl)pyrazolo(1,5-a)pyrimidin-2-ol
Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 2-[(diethoxyphosphinothioyl)oxy]-5-methyl-, ethyl ester
Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 2-hydroxy-5-methyl-, ethyl ester, O-ester with O,O-diethyl phosphorothioate
Caswell No. 714D
Pyrazophos [BSI:ISO]
Pyrazolo(1,5-a)pyrimidine-6-carboxylic acid, 2-hydroxy-5-methyl-, ethyl ester, O-ester with O,O-diethyl phosphorothioate
EINECS 236-656-1
HOE 02873
UNII-BEG0A8I17D
EPA Pesticide Chemical Code 447500
BRN 0577209
ETHYL 2-DIETHOXYPHOSPHINOTHIOYLOXY-5-METHYLPYRAZOLO(1,5-A)PYRIMIDINE-6-CARBOXYLATE
2-(O,5a]pyrimidine
PYRAZOPHOS [MI]
PYRAZOPHOS [ISO]
2-(O,O-Diethyl-thionophosphoryl)-5-methyl-6-carbethoxy-pyrazolo-(1,5a)pyrimidine
Ethyl 2-diethoxythiophosphoryloxy-5-methylpyrazolo(1,5-a)pyrimidine-6-carboxylate
Pyrazolo-(1,5a)pyrimidine, 2-(O,O-diethyl-thionophosphoryl)-5-methyl-6-ethoxycarbonyl-
SCHEMBL22029
MLS000028239
O,O-Diethyl O-(5-methyl-6-(ethoxycarbonyl)-pyrazolo-(1,5-a)-pyrimid-2-yl)-thionophosphate [ISO:BSI]
orb1705797
CHEMBL1537719
HMS2273B24
Tox21_301359
NSC232671
AKOS040744525
NCGC00255857-01
SMR000009834
CAS-13457-18-6
HY-120729
CS-0078915
NS00010879
Pyrazophos, PESTANAL(R), analytical standard
C18761
WLN: T56 ANN FNJ COPS&O2&O2 G1 HVO2
Q302171
SR-01000321319
SR-01000321319-1
Ethyl 2-hydroxy-5-methylpyrazolo(1,O-diethylphosphorothioate
Pyrazolo[1, 2-(O,O-diethyl thionophosphoryl)-5-methyl-6-ethoxycarbonyl-
Pyrazolo[1, 2-[(diethoxyphosphinothioyl)oxy]-5-methyl-, ethyl ester
2-(O,O-Diethyl thionophosphoryl)-5-methyl-6-carbethoxy-pyrazolo(1,5a)pyrimidin
2-(O,O-Diethyl-thionophosphoryl)-5-methyl-6-carbethoxy-pyrazolo-(1,5-a)pyrimidine
2-(O,O-Diethylthionophosphoryl)-5-methyl-6-carbethoxy-pyrazolo-(1,5a)pyrimidine
ethyl 2-[(diethoxy phosphinothioyl)oxy]-5-methyl pyrazolo[1,5-a]pyrimidine-6-carboxylate
Ethyl 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
Ethyl 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate #
Pyrazolo(1,5a)pyrimidine, 2-(O,O-diethyl thionophosphoryl)-5-methyl-6-ethoxycarbonyl-
Pyrazolo[1, 2-hydroxy-5-methyl-, ethyl ester, O-ester with O,O-diethyl phosphorothioate
2-(Diethoxy-thiophosphoryloxy)-5-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester
Ethyl 2-hydroxy-5-methylpyrazolo(1,5-a)pyrimidine-6-carboxylate O-ester of O,O-diethylphosphorothioic acid
Phosphorothioic acid,O-diethyl ester O-ester with (6-ethoxycarbonyl-5-methyl)pyrazolo(1,5-pyrimidin-2-ol)