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Ethyl 2-diethoxyphosphorylacetate

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Identification
Molecular formula
C10H21O6P
CAS number
67263-83-4
IUPAC name
ethyl 2-diethoxyphosphorylacetate
State
State

At room temperature, ethyl 2-diethoxyphosphorylacetate exists as a liquid. Due to its liquid state, it is important to handle with appropriate care to avoid spills and ensure accurate measurements in applications.

Melting point (Celsius)
-65.00
Melting point (Kelvin)
208.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
242.22g/mol
Molar mass
242.2210g/mol
Density
1.0850g/cm3
Appearence

Ethyl 2-diethoxyphosphorylacetate is typically a colorless to pale yellow liquid. Due to its organic nature, it has an oily consistency and is often stored in a tightly sealed container to prevent contamination and evaporation.

Comment on solubility

Solubility of Ethyl 2-Diethoxyphosphorylacetate

Ethyl 2-diethoxyphosphorylacetate, as a phosphorus-containing organic compound, demonstrates notable solubility characteristics that merit discussion. The solubility can be influenced by several factors, including:

  • Polarity: This compound features both polar and nonpolar regions due to the presence of ethoxy groups and the acetate moiety.
  • Solvent Interaction: Ethyl 2-diethoxyphosphorylacetate is likely to dissolve well in polar organic solvents such as ethanol or methanol, due to the interaction between the polar functional groups.
  • Water Solubility: Although the presence of ester groups can enhance solubility in water, the overall hydrophobic nature of the compound may limit its solubility in aqueous solutions.

In summary, while ethyl 2-diethoxyphosphorylacetate is generally more soluble in polar organic solvents, its solubility in water is not significant. The varying solubility behavior showcases the importance of solvent choice when considering the use of this compound in chemical reactions or applications.

Interesting facts

Interesting Facts about Ethyl 2-Diethoxyphosphorylacetate

Ethyl 2-diethoxyphosphorylacetate is a fascinating compound primarily known for its role in organic synthesis and as an important intermediate in the pharmaceutical industry. Here are some insightful aspects about this compound:

  • Versatile Synthetic Applications: This compound is often utilized in the synthesis of various biologically active molecules, including pharmaceuticals and agrochemicals.
  • Phosphorylation Reactions: It acts as a phosphorylating agent, making it invaluable in the preparation of phosphate esters, which are crucial in biochemistry.
  • Potential in Drug Development: Its ability to modify biological activity makes it a target for the development of new drugs, particularly those that require a phosphate moiety to exhibit their therapeutic effects.
  • Study of Organophosphates: Ethyl 2-diethoxyphosphorylacetate is part of a larger class of organophosphorus compounds, which are studied for their insecticidal and herbicidal properties.
  • Phosphorus-Containing Compounds in Nature: Phosphorus is an essential element in life, as reflected in this compound's structural characteristics, which are similar to nucleotides found in DNA and RNA.
  • Research Interest: Due to its unique structure, researchers frequently examine this compound for its potential reactivity and interactions with enzymes and biological systems, offering insights into its mode of action.

As a student of chemistry, one cannot overlook the significance of compounds like ethyl 2-diethoxyphosphorylacetate, as they bridge the gap between fundamental research and practical applications in medicine and agriculture.

In the words of a noted chemist, "The beauty of chemistry lies in the connections we can create through the manipulation of molecules." This compound is a perfect representation of such possibilities.

Synonyms
Triethyl phosphonoacetate
867-13-0
Ethyl (diethoxyphosphoryl)acetate
Diethyl ethoxycarbonylmethanephosphonate
Ethyl (diethylphosphono)acetate
Triethyl phosphonoethanoate
Acetic acid, (diethoxyphosphinyl)-, ethyl ester
Diethyl carbethoxymethylphosphonate
Diethyl carboethoxymethylphosphonate
Ethyl diethoxyphosphoryl acetate
TL 465
ETHYL (DIETHOXYPHOSPHINYL)ACETATE
Phosphonoacetic acid, triethyl ester
Acetic acid, phosphono-, triethyl ester
Diethyl phosphonoacetic acid, ethyl ester
NSC 13898
NSC 16128
(Ethoxycarbonylmethyl)diethoxyphospshine oxide
Acetic acid, 2-(diethoxyphosphinyl)-, ethyl ester
EINECS 212-757-6
Acetic acid, (diethylphosphono)-, ethyl ester
DTXSID4041573
carbethoxymethyldiethyl phosphonate
Acetic acid, diethylphosphono-, ethyl ester
NSC-13898
NSC-16128
DTXCID2021573
EC 212-757-6
Diethyl ethoxycarbonylmethylphosphonate
TL-465
022826171T
diethyl phosphonoacetic acid ethyl ester
carbethoxymethyl diethyl phosphonate
Acetic acid, phosphono, triethyl ester
Acetic acid, diethylphosphono, ethyl ester
Acetic acid, (diethylphosphono), ethyl ester
Acetic acid, phosphono, triethyl ester (9CI)
Acetic acid, (diethoxyphosphinyl), ethyl ester
Acetic acid, phosphono-, triethyl ester (9CI)
Acetic acid, 2(diethoxyphosphinyl), ethyl ester
212-757-6
Ethyl 2-(diethoxyphosphoryl)acetate
ethyl 2-diethoxyphosphorylacetate
Diethylphosphonoacetic Acid Ethyl Ester
MFCD00009177
TriethylPhosphonoacetate-d2
Ethyl Diethylphosphonoacetate
O,O-Diethyl ethoxycarbonylmethyl phosphonate
ethyl 2-(diethyl phosphono)acetate
Phosphonoacetic Acid Triethyl Ester
Acetic acid, triethyl ester
WLN: OPO&O&2&2&1VO2
triethyl phosphono acetate
Triethylphosphonoacetate
ethyl(diethoxyphosphoryl)acetate
UNII-022826171T
Triethylophosphonoacetate
ethyldiethylphosphonoacetate
(diethoxy-phosphoryl)-acetic acid ethyl ester
ethyl diethylphosphonoactate
SCHEMBL16047
CBDivE_001998
ethyl diethoxyphosphinylacetate
ethyl diethoxyphosphorylacetate
ethyl(diethoxyphosphinyl)acetate
Triethyl phosphonoacetate, 98%
CHEMBL3185304
ethyl2-(diethoxyphosphoryl)acetate
phosphonoacetic acid-triethyl ester
BCP24434
Ethyl (diethoxy-phosphoryl)-acetate
Ethyl (diethoxyphosphoryl)acetate #
Ethyl-2-(diethoxyphosphoryl)acetate
HY-Y0677
NSC13898
NSC16128
STR01192
ethyl-2-(diethoxylphosphoryl)acetate
Tox21_302053
ethyl 2-(diethoxyphosphoryl)ethanoate
STL477594
diethylethoxycarbonylmethyl-phosphonate
AKOS009156982
CS-W009140
diethoxyphosphorylactic acid ethyl ester
FT28426
NCGC00255680-01
CAS-867-13-0
(Diethoxyphosphoryl)acetic acid ethyl ester
2-diethoxyphosphorylacetic acid ethyl ester
Diethyl [(ethoxycarbonyl)methyl]phosphonate
DB-013131
(diethoxyphosphoryl)-acetic acid ethyl ester
D1523
NS00003566
EN300-52552
Triethyl phosphonoacetate, purum, >=97.0% (GC)
Ethanoic acid, 2-(diethoxyphosphinyl)-, ethyl ester
Q7841458
F0001-2154
InChI=1/C8H17O5P/c1-4-11-8(9)7-14(10,12-5-2)13-6-3/h4-7H2,1-3H
Diethyl ethoxycarbonylmethylphosphonate;2-(Diethoxyphosphinyl)acetic acid ethyl ester;(Diethoxyphosphinyl)acetic acid ethyl ester