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Tramadol Hydrochloride

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Identification
Molecular formula
C16H26ClNO2
CAS number
27203-92-5
IUPAC name
ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium;chloride
State
State
Tramadol hydrochloride is a solid at room temperature, typically found in powder form. Due to its crystalline structure, it maintains its solid state under standard conditions.
Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
356.60
Boiling point (Kelvin)
629.75
General information
Molecular weight
299.84g/mol
Molar mass
299.8410g/mol
Density
1.3537g/cm3
Appearence
Tramadol hydrochloride appears as a white to off-white crystalline powder. It is typically odorless and has a bitter taste. The powder is highly soluble in water and methanol and slightly soluble in ethanol.
Comment on solubility

Solubility of Ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium Chloride

Ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium chloride possesses notable characteristics regarding its solubility, primarily influenced by its ionic nature and the functional groups present in the molecule. Here are some key points to consider:

  • Highly Soluble in Water: Due to the presence of an ammonium group, which readily interacts with water molecules, this compound is expected to exhibit high solubility in aqueous solutions.
  • Effect of Hydroxyl Groups: The two hydroxyl groups in its structure enhance its polarity, further promoting solubility in water.
  • Solvent Interaction: The solubility might vary with different solvents, generally being less soluble in non-polar solvents due to its polar nature.
  • Temperature Dependence: Increased temperature may improve solubility, as it usually does for ionic compounds.

In summary, the solubility of ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium chloride is predominantly influenced by its ionic and polar characteristics, making it highly soluble in polar solvents, particularly water. This property is critical for applications involving biological and chemical interactions where solubility can significantly affect behavior and reactivity.

Interesting facts

Interesting Facts about Ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium Chloride

Ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium chloride, often referred to as a derivative of phenyl ethanolamine, is an intriguing compound with various applications across fields such as pharmacology and biochemistry. Here are some noteworthy aspects of this compound:

  • Pharmacological Significance: This compound is typically studied for its potential role in influencing neurotransmitter systems in the brain, making it of interest in the development of treatments for psychological and neurological disorders.
  • Natural Compound Relations: Its structure is reminiscent of natural compounds found in plants, suggesting that it may share similar biological activities, which could lead to breakthroughs in herbal medicine.
  • Applications in Synthesis: This compound serves as a precursor for the synthesis of various other biologically active molecules, showcasing its versatility and importance in organic synthesis.
  • Steric Hindrance: The unique combination of hydroxy groups and ethylamine contributes to its steric features, which can affect interaction with biological targets and influence its potency.
  • Role as a Bioactive Compound: Interestingly, compounds like this have demonstrated potential antimicrobial properties, suggesting avenues for antibiotic development.

In conclusion, ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium chloride holds promise not just as a chemical compound but also has the potential to contribute significant advancements in medicine and pharmacology. Its unique properties and structural attributes make it a compound worth exploring further.

Synonyms
BENZO[C][1,2,5]OXADIAZOLE-5-BORONICACID
AKOS025116943
ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]azanium;chloride