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Ethyl glycolate

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Identification
Molecular formula
C4H8O3
CAS number
623-50-7
IUPAC name
ethyl 2-hydroxyacetate
State
State

At room temperature, ethyl glycolate is found in the liquid state. It is volatile and has a light consistency compared to heavier organic solvents.

Melting point (Celsius)
-26.00
Melting point (Kelvin)
247.15
Boiling point (Celsius)
160.20
Boiling point (Kelvin)
433.35
General information
Molecular weight
104.10g/mol
Molar mass
104.1040g/mol
Density
1.0470g/cm3
Appearence

Ethyl glycolate is a colorless liquid that can also appear as a pale yellow liquid. It has a sweet, fruity odor which makes it identifiable. It is typically clear and not highly viscous.

Comment on solubility

Solubility of Ethyl 2-Hydroxyacetate

Ethyl 2-hydroxyacetate, known as a versatile solvent and intermediate, exhibits interesting solubility characteristics:

  • Solubility in Water: Ethyl 2-hydroxyacetate is moderately soluble in water due to its ability to form hydrogen bonds through the hydroxyl (-OH) group.
  • Solubility in Organic Solvents: It is highly soluble in a variety of organic solvents, such as:
    • Ethyl acetate
    • Acetone
    • Chloroform

This compound’s solubility profile is primarily influenced by its molecular structure, with the ester and hydroxyl groups playing significant roles in solvent interactions. Consequently, it serves as an effective solvent in chemical reactions and formulations.

In summary, the solubility of ethyl 2-hydroxyacetate highlights its dual nature, making it a valuable component across various applications:

  1. Moderate solubility in polar solvents (e.g., water)
  2. High solubility in non-polar solvents (e.g., organic solvents)

This balance makes ethyl 2-hydroxyacetate a compound of interest for many scientific and industrial applications.

Interesting facts

Interesting Facts about Ethyl 2-Hydroxyacetate

Ethyl 2-hydroxyacetate, commonly known in some contexts as ethyl glycolate, is a versatile compound with numerous applications in both industrial and consumer products. This compound is particularly valued for its unique properties and wide-ranging uses.

Key Attributes

  • Solvent Properties: Ethyl 2-hydroxyacetate serves as an effective solvent for various coatings, inks, and adhesives due to its ability to dissolve polar and non-polar substances alike.
  • Use in Pharmaceuticals: This compound is employed in the pharmaceutical industry as an intermediate in the synthesis of various medications, contributing to drug formulation and stability.
  • Flavor and Fragrance: Ethyl 2-hydroxyacetate has applications in the flavor and fragrance industry, where it is used to impart fruity notes, particularly in products designed to mimic the scent of ripe fruits.

Chemical Behavior

This compound exhibits chiral characteristics, leading to its potential use in asymmetric synthesis processes in advanced chemistry.

Trivia

A few interesting points to note about ethyl 2-hydroxyacetate include:

  • It can be produced through the esterification of glycolic acid with ethanol, a reaction that highlights the principles of organic synthesis.
  • Its molecular structure allows for a certain degree of hydrogen bonding, which enhances its solvent capabilities.
  • Ethyl 2-hydroxyacetate may sometimes be mentioned in discussions about the safety and environmental impacts of ester compounds, as it is considered less toxic compared to many solvents.

In summary, ethyl 2-hydroxyacetate is much more than just a simple compound; it plays a vital role across various sectors, illustrating the importance of chemical compounds in everyday applications.

Synonyms
Ethyl glycolate
623-50-7
Ethyl hydroxyacetate
Ethyl glycollate
GLYCOLIC ACID, ETHYL ESTER
Hydroxyacetic acid ethyl ester
Acetic acid, 2-hydroxy-, ethyl ester
NSC 8835
EINECS 210-798-4
BRN 1743766
C306E91WFK
AI3-03541
NSC-8835
4-03-00-00580 (Beilstein Handbook Reference)
Acetic acid, hydroxy, ethyl ester
Acetic acid, 2hydroxy, ethyl ester
ethyl 2-hydroxyacetate
Acetic acid, hydroxy-, ethyl ester
MFCD00021970
Glycolic Acid Ethyl Ester
UNII-C306E91WFK
ethyl-hydroxyacetate
Ethyl 2-Hydroxyacetate; Ethyl Hydroxyacetate; Glycolic Acid Ethyl Ester; 2-Hydroxyacetic Acid Ethyl Ester; NSC 8835
Ethyl glycolate, 98%
HOCH2COOC2H5
SCHEMBL5075
hydroxyacetic acid ethylester
WLN: Q1VO2
hydroxy acetic acid ethyl ester
hydroxy-acetic acid ethyl ester
DTXSID5060772
ZANNOFHADGWOLI-UHFFFAOYSA-
NSC8835
2-hydroxy-acetic acid ethyl ester
AKOS009157950
CS-W019892
AS-17295
BP-21252
SY002762
DB-001024
G0242
NS00022536
EN300-42326
Q27275115
F0001-1672
Z385458066
InChI=1/C4H8O3/c1-2-7-4(6)3-5/h5H,2-3H2,1H3