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Ethyl benzoxazole-3-carboxylate

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Identification
Molecular formula
C10H9NO4
CAS number
612-13-5
IUPAC name
ethyl 2-oxo-1,3-benzoxazole-3-carboxylate
State
State

At room temperature, ethyl benzoxazole-3-carboxylate is in a solid state.

Melting point (Celsius)
44.00
Melting point (Kelvin)
317.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
205.19g/mol
Molar mass
205.1910g/mol
Density
1.3430g/cm3
Appearence

Ethyl benzoxazole-3-carboxylate appears as a crystalline solid. It is typically white in color and may have a slight odor depending on purity.

Comment on solubility

Solubility of Ethyl 2-oxo-1,3-benzoxazole-3-carboxylate

Ethyl 2-oxo-1,3-benzoxazole-3-carboxylate is a fascinating compound in terms of solubility. Its solubility characteristics can be summarized as follows:

  • Polar Nature: The presence of both the carbonyl group and the carboxylate moiety in its structure contributes to a polar character.
  • Solvent Compatibility: This compound tends to be soluble in polar organic solvents such as methanol and ethanol. It also shows limited solubility in less polar solvents.
  • Hydrogen Bonding: The carboxylate group can engage in hydrogen bonding, which enhances its solubility in water to some extent, although it may not be highly soluble.

In practical applications, the solubility profile of ethyl 2-oxo-1,3-benzoxazole-3-carboxylate can affect its behavior in chemical reactions, making it essential to consider when designing experiments. As noted, "Like dissolves like," which underlines the importance of matching solvent polarity with the compound's characteristics.

Overall, understanding the solubility of this compound is crucial as it plays a significant role in its reactivity, bioavailability, and overall performance in various applications.

Interesting facts

Interesting Facts about Ethyl 2-oxo-1,3-benzoxazole-3-carboxylate

Ethyl 2-oxo-1,3-benzoxazole-3-carboxylate is a fascinating organic compound that merges both benzoxazole and ester functionalities, making it of considerable interest in the field of medicinal chemistry. Here are some compelling points about this compound:

  • Diverse Applications: This compound is often explored for its potential as a pharmacological agent. Its unique structure enables it to interact with various biological targets, possibly leading to the development of new drugs.
  • Research Importance: The synthesis and study of this compound can provide insights into the reactivity of benzoxazole derivatives, which are known for their *antimicrobial*, *anticancer*, and *antioxidant* properties.
  • Structural Features: The presence of the 2-oxo group contributes to the compound's chemical reactivity. This feature can enhance electrophilic aromatic substitution reactions, making it a valuable building block in organic synthesis.
  • Fluorescent Properties: Some derivatives of benzoxazole compounds exhibit fluorescent behavior. This means that ethyl 2-oxo-1,3-benzoxazole-3-carboxylate could potentially be utilized in various imaging applications, such as in biological studies.
  • Environmental Relevance: By studying the biodegradability and ecological impact of this compound, researchers can better understand its role in environmental chemistry, particularly when used in industrial applications.

The exploration of ethyl 2-oxo-1,3-benzoxazole-3-carboxylate not only advances chemical knowledge but also holds the promise of contributing to innovative solutions in healthcare and environmental science. Its multifaceted characteristics make it a subject of much curiosity and potential research opportunities.

Synonyms
17280-90-9
BRN 0201878
3(2H)-BENZOXAZOLECARBOXYLIC ACID, 2-OXO-, ETHYL ESTER
3-Etoksykarbonylo-benzoksazolon-2
3-Etoksykarbonylo-benzoksazolon-2 [Polish]
2-Oxo-3(2H)-benzoxazolecarboxylic acid ethyl ester
ETHYL 2,3-DIHYDRO-2-OXO-3-BENZOXAZOLECARBOXYLATE
DTXSID40169403
2-27-00-00223 (Beilstein Handbook Reference)
DTXCID1091894
659-529-6
Ethyl 2-oxobenzo[d]oxazole-3(2H)-carboxylate
MLS000518865
ethyl 2-oxo-1,3-benzoxazole-3(2H)-carboxylate
ethyl 2-oxo-2,3-dihydro-1,3-benzoxazole-3-carboxylate
SMR000129285
ethyl 2-oxo-1,3-benzoxazole-3-carboxylate
Maybridge3_003262
Opera_ID_1347
CHEMBL1437940
HMS1440E06
HMS2474M20
CCG-54704
STK672525
AKOS005592950
ethyl benzoxazolin-2-one-3-carboxylate
IDI1_014649
NCGC00245942-01
ST079305
CS-0336859
ethyl 2-oxo-3-hydrobenzoxazole-3-carboxylate
SR-01000643785-1
BRD-K13118622-001-16-4