Ethyl 3-(2-sulfamoylphenyl)prop-2-enoate

Identification

Molecular formula

C₁₁H₁₃NO₄S

CAS number

915783-27-4

IUPAC name

ethyl 3-(2-sulfamoylphenyl)prop-2-enoate

State

The compound is in solid state at room temperature.

Melting point (Celsius)

153.50

Melting point (Kelvin)

426.70

Boiling point (Celsius)

436.50

Boiling point (Kelvin)

709.70

General information

Molecular weight

265.28g/mol

Molar mass

265.2830g/mol

Density

1.3122g/cm³

Appearence

Ethyl 3-(2-sulfamoylphenyl)prop-2-enoate typically appears as a solid crystalline powder. It is often off-white to pale yellow in color and can exhibit a mild characteristic odor.

Comment on solubility

Solubility of Ethyl 3-(2-sulfamoylphenyl)prop-2-enoate

Ethyl 3-(2-sulfamoylphenyl)prop-2-enoate, a compound featuring both an ethyl group and a sulfonamide moiety, exhibits interesting solubility characteristics that can be influenced by its molecular structure. Here are some key points regarding its solubility:

Polar versus Nonpolar: The sulfonamide group introduces significant polarity to the molecule, which generally enhances its solubility in polar solvents like water.
Solvent Compatibility: This compound is likely to dissolve in ethanol and dimethyl sulfoxide (DMSO), both of which can effectively solvate polar compounds.
Temperature Dependence: Like many organic compounds, its solubility may increase with rising temperature, making it more favorable for dissolution in warmer solutions.
pH Influence: The sulfonamide nature could lead to changes in solubility at different pH levels, which may impact its ionization and solubility profile.

In conclusion, while specific solubility values may vary considerably based on environmental conditions and the presence of other solutes, this compound's unique features suggest promising solubility in a variety of polar solvents.

Interesting facts

Interesting Facts About Ethyl 3-(2-Sulfamoylphenyl)prop-2-enoate

Ethyl 3-(2-sulfamoylphenyl)prop-2-enoate is a compound that captivates the interest of chemists due to its unique structural features and potential applications. Here are some noteworthy aspects to consider:

Sulfamoyl Group: The presence of the sulfamoyl group (-SO₂NH₂) is particularly intriguing, as it is associated with a variety of biological activities. Compounds containing this group have been studied for their antimicrobial properties.
Biological Significance: Research has indicated that derivatives of sulfonamides, which include the sulfamoyl moiety, demonstrate significant efficacy in medicinal chemistry, particularly in developing drugs to combat bacterial infections.
Versatile Functionality: The ethyl ester component provides versatility in synthetic chemistry, allowing for various modifications that can enhance its properties or create novel compounds.
Potential for Drug Development: Researchers are continuously looking at compounds like ethyl 3-(2-sulfamoylphenyl)prop-2-enoate for their potential as lead structures in drug design.

The structure of this compound is also notable for its geometric isomerism, highlighting the importance of stereochemistry in determining chemical reactivity and biological activity.

In summary, this compound is not just a chemical entity; it represents a bridge between synthetic organic chemistry and potential therapeutic applications, making it a compelling topic for further exploration.