Skip to main content

Ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate

ADVERTISEMENT
Identification
Molecular formula
C11H8N2O6
CAS number
[CAS Number not found]
IUPAC name
ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate
State
State
This compound is a solid at room temperature, exhibiting a crystalline form with a yellow hue due to the presence of the nitro group.
Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
484.00
Boiling point (Kelvin)
757.15
General information
Molecular weight
264.19g/mol
Molar mass
264.2110g/mol
Density
1.4230g/cm3
Appearence

The compound appears as a yellow crystalline solid. It is characterized by its distinct coloration, which is typical for compounds containing nitro groups and heterocyclic structures like isoxazole and furan.

Comment on solubility

Solubility of Ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate

The solubility of ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate can be quite interesting due to its unique structural features. This compound is influenced by a variety of factors affecting its solubility, which include:

  • Polarity: The presence of both the nitro group and the isoxazole ring can increase the polarity of the compound, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The carboxylate group may participate in hydrogen bonding, which can further affect solubility in different solvent systems.
  • pH Sensitivity: The solubility of this compound may change with the pH of the solution due to the ionization of the carboxylic acid group.

Generally, compounds similar in structure to ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate tend to exhibit moderate solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) while potentially being sparingly soluble in water. Thus, it may be beneficial to explore various solvent systems to attain desired solubility levels.

In summary, while the solubility of this compound is influenced by several structural characteristics, it likely showcases a balance of favorable interactions in compatible solvents, making it a topic of continued interest in chemical research and applications.

Interesting facts

Interesting Facts about Ethyl 3-(5-Nitro-2-furyl)isoxazole-4-carboxylate

Ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate is a fascinating compound that captures the interest of chemists due to its unique structure and potential applications. Here are some intriguing aspects of this compound:

  • Cyclic Structure: The compound features a heterocyclic isoxazole ring, which is known for its interesting reactivity and the ability to form various derivatives.
  • Biological Significance: Compounds containing nitro groups, like the 5-nitro-2-furyl moiety, often exhibit notable biological activity. They can be explored for their applications in pharmaceuticals, particularly in the search for new antimicrobial and anticancer agents.
  • Versatile Synthetic Pathways: The synthesis of ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate can be achieved through various chemical reactions, making it an excellent compound for students to study synthetic organic chemistry.
  • Research Applications: With ongoing studies about the compound's potential uses, researchers are examining its role in organic electronics and materials science, where isoxazole derivatives have shown promise.

A notable quote in the field of chemistry states, "Chemistry is the toolbox of innovation." Ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate exemplifies how compounds in the lab could lead to groundbreaking discoveries in medicinal chemistry and material science.

As students and scientists continue to explore the depths of chemical compounds, the study of such unique structures becomes ever more crucial. Ethyl 3-(5-nitro-2-furyl)isoxazole-4-carboxylate stands out not only for its intriguing structure but also for the potential it holds in advancing various scientific fields.

Synonyms
4-ISOXAZOLECARBOXYLIC ACID, 3-(5-NITRO-2-FURYL)-, ETHYL ESTER
21787-30-4
BRN 0548586
DTXSID40176192
3-(5-Nitro-2-furyl)-4-isoxazolecarboxylic acid ethyl ester