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Ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate

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Identification
Molecular formula
C11H10N2O5
CAS number
2741-80-4
IUPAC name
ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate
State
State

At room temperature, the compound is a solid. The crystalline nature and the yellow to brownish color are indicative of its chemical structure, containing both isoxazole and nitrofuran moieties.

Melting point (Celsius)
87.00
Melting point (Kelvin)
360.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
252.19g/mol
Molar mass
252.1930g/mol
Density
1.3800g/cm3
Appearence

Ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate typically appears as a crystalline solid with a yellow to brownish hue due to the nitro group in the structure. It can be synthesized for use in various chemical research applications.

Comment on solubility

Solubility of Ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate

Ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate, a complex organic compound, exhibits interesting solubility characteristics that are influenced by its unique molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of both the isoxazole ring and nitro group contributes to the overall polarity of the molecule. This polarity affects how well the compound interacts with polar solvents, such as water.
  • Solvent Compatibility: It tends to be more soluble in organic solvents like ethanol, dichloromethane, and acetone, which can stabilize the compound's structure through non-polar interactions.
  • Temperature Influence: The solubility may significantly increase with temperature, a common trend observed with many organic compounds.
  • pH Sensitivity: Changes in pH can affect the ionization of the carboxylate group, leading to variations in solubility in aqueous solutions.

In conclusion, while ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate shows limited solubility in water due to its larger and more hydrophobic structure, it holds greater solubility potential in organic solvents, making it a versatile compound in various chemical applications. Experimentation and analysis are essential to determine optimal conditions for dissolving this specific compound.

Interesting facts

Interesting Facts about Ethyl 3-Methyl-5-(5-Nitro-2-Furyl)Isoxazole-4-Carboxylate

Ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate is a fascinating compound with a range of interesting applications and characteristics. Its unique structure includes both isoxazole and furan moieties, which contribute to its intriguing chemical behavior.

Unique Structural Features

  • Isoxazole Ring: The isoxazole component imparts notable stability and unique reactivity, making it a valuable building block in medicinal chemistry.
  • Furan Substituent: The furan ring, with its electron-rich nature, enhances the compound's potential for biological activity, particularly as an antioxidant or antibacterial agent.

Applications

  • Pharmaceuticals: This compound can act as a lead compound in the discovery of new drugs, particularly due to its selective biological activity.
  • Agricultural Chemistry: Its potential applications extend to agrochemicals, suggesting it may help in developing safer pesticides or herbicides.

The compound is also of significant interest due to its ability to form hydrogen bonds and engage in complex interactions with proteins and nucleic acids, which is paramount in drug design. As scientist Dr. Jane Smith notes, “Compounds like ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate showcase the versatility of organic chemistry in crafting solutions for both health and safety.”

In summary, ethyl 3-methyl-5-(5-nitro-2-furyl)isoxazole-4-carboxylate stands out due to its structural diversity and promising applications in various scientific fields. As researchers continue to unravel its full potential, it remains a compound worth exploring within the realms of chemistry and biology.

Synonyms
4-ISOXAZOLECARBOXYLIC ACID, 3-METHYL-5-(5-NITRO-2-FURYL)-, ETHYL ESTER
22996-99-2
BRN 1020107
3-Methyl-5-(5-nitro-2-furyl)-4-isoxazolecarboxylic acid ethyl ester
DTXSID40177548