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Ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate

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Identification
Molecular formula
C11H13NO3
CAS number
37251-69-1
IUPAC name
ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
State
State
At room temperature, ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate typically appears as a solid.
Melting point (Celsius)
59.50
Melting point (Kelvin)
332.65
Boiling point (Celsius)
335.40
Boiling point (Kelvin)
608.55
General information
Molecular weight
207.22g/mol
Molar mass
207.2200g/mol
Density
1.1540g/cm3
Appearence

Ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate is typically characterized by its crystalline solid form. The appearance may vary in texture and color, but it generally exists as a colorless or pale yellow solid under normal conditions.

Comment on solubility

Solubility of Ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate

Ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate is a compound that exhibits interesting solubility characteristics. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of polar functional groups in the structure tends to increase its solubility in polar solvents such as water and methanol.
  • Temperature: Solubility can also be affected by temperature, with many compounds becoming more soluble as the temperature increases.
  • pH Levels: Alterations in the pH of the solvent may lead to changes in solubility, particularly for compounds with acidic or basic groups.

In general, ethanol and other organic solvents are likely to provide better solubility compared to water, given the ethyl group present in its structure which encourages interaction with organic solvents. As a rule of thumb, like dissolves like, meaning that this compound may dissolve more readily in non-polar to moderately polar solvents than in highly polar solvents.

To summarize, the solubility of ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate can be attributed to a combination of its chemical structure and the solvent characteristics, making it a compound of interest for various chemical applications.

Interesting facts

Interesting Facts About Ethyl 3,4-Dihydro-2H-1,4-benzoxazine-2-carboxylate

Ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate is a fascinating compound that holds special interest in the fields of organic chemistry and pharmacology. Here are some noteworthy points about this compound:

  • Structure Significance: The unique benzoxazine ring structure features fused heteroatoms, which enhances its reactivity and potential application in various chemical reactions.
  • Biological Activity: Compounds like ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate are known for their diverse biological activities. Research indicates potential applications in developing anti-inflammatory and anticancer agents.
  • Synthesis Pathways: The synthesis of this compound can be achieved through various methods, including cyclization reactions which allow for the introduction of functional groups that can help tailor its properties for specific applications.
  • Pharmaceutical Potential: Due to its structural versatility, it has garnered interest for use in pharmaceuticals, possibly serving as a scaffold for novel drug compounds.
  • Research Development: Ongoing studies are exploring its interaction mechanisms at a molecular level to aid in the design of more effective therapeutic agents.

In summary, ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate exemplifies the intersection of synthetic chemistry and biological research, making it a target of scientific investigation for both its unique structural features and its potential health benefits.

Synonyms
22244-22-0
ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate
ETHYL 3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-2-CARBOXYLATE
MFCD01663859
ethyl benzomorpholine-2-carboxylate
CHEMBL4868317
DTXSID40944898
BRN 0990855
3,4-Dihydro-2H-1,4-benzoxazine-2-carboxylic acid ethyl ester
2H-1,4-BENZOXAZINE-2-CARBOXYLIC ACID, 3,4-DIHYDRO-, ETHYL ESTER
RefChem:1084829
SCHEMBL924887
FGYXHLIMQKWPIL-UHFFFAOYSA-N
DTXCID801373228
AR3125
BDBM50576034
SBB093861
STK909181
AKOS002199221
AKOS016305636
AB09689
SY122955
CS-0038273
EN300-313163
2-ethoxycarbonyl-3,4-dihydro-2H-1,4-benzoxazine
5X-0292
F306434
ethyl 2H,3H,4H-benzo[e]1,4-oxazine-2-carboxylate
2(R,S)-ethoxycarbonyl-3,4-dihydro-2H-1,4-benzoxazine
(+/-)-Ethyl 3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate
ETHYL3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-2-CARBOXYLATE