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Ethyl gallate

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Identification
Molecular formula
C9H10O5
CAS number
831-61-8
IUPAC name
ethyl 3,4,5-trihydroxybenzoate
State
State

At room temperature, ethyl gallate is a solid.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.00
Boiling point (Celsius)
399.20
Boiling point (Kelvin)
672.35
General information
Molecular weight
198.17g/mol
Molar mass
198.1730g/mol
Density
1.3470g/cm3
Appearence

Ethyl gallate is typically encountered as a white to off-white crystalline powder. It is sometimes seen as colorless crystals.

Comment on solubility

Solubility of Ethyl 3,4,5-trihydroxybenzoate

Ethyl 3,4,5-trihydroxybenzoate, with the chemical formula C10H12O5, is known for its intriguing solubility properties. This compound exhibits a moderate solubility profile, influenced by the presence of multiple hydroxyl groups that increase its polarity.

Key Solubility Insights:

  • Solvents: It is more soluble in polar solvents such as water and ethanol due to hydrogen bonding capabilities.
  • Temperature Dependence: The solubility often increases with temperature, which is characteristic of many organic compounds.
  • pH Influence: The solubility can be affected by the pH of the solution, as the ionization of hydroxyl groups may occur in more alkaline or acidic conditions.
  • Crystallization: In lower polar environments, ethyl 3,4,5-trihydroxybenzoate may crystallize out, highlighting its limited solubility in nonpolar solvents.

This compound's solubility characteristics are paramount for various applications, such as in pharmaceuticals and cosmetics, where its efficacy can significantly depend on how well it dissolves in the chosen formulations. Understanding these solubility dynamics not only facilitates its practical use but also reveals the underlying chemical interactions that govern its behavior in different environments.

Interesting facts

Interesting Facts about Ethyl 3,4,5-trihydroxybenzoate

Ethyl 3,4,5-trihydroxybenzoate, also known as ethyl gallate, is a fascinating compound that exhibits both industrial and biological significance. This compound is primarily derived from gallic acid and is notable for its potent antioxidant properties. Here are some intriguing aspects about it:

  • Antioxidant Activity: Ethyl 3,4,5-trihydroxybenzoate is recognized for its ability to scavenge free radicals, which helps in combating oxidative stress in living organisms.
  • Antimicrobial Properties: Research has indicated that this compound possesses antimicrobial effects, making it a potential candidate for use in food preservation and health products.
  • Cosmetic Applications: Due to its antioxidant and anti-inflammatory characteristics, it is often incorporated in cosmetic formulations to enhance skin health and provide protection against environmental stressors.
  • Chemical Synthesis: Ethyl 3,4,5-trihydroxybenzoate can be synthesized through esterification of gallic acid with ethanol, demonstrating the simplicity of its preparation from natural sources.
  • Research Insights: Recent studies have explored the role of ethyl gallate in various fields, including pharmaceuticals and nutraceuticals, highlighting its potential in drug development.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” Ethyl 3,4,5-trihydroxybenzoate serves as a prime example of how a single compound can inspire research and innovation across multiple disciplines. Its applications are as varied as they are intriguing, making it an essential subject of study in chemistry and beyond.

Synonyms
ETHYL GALLATE
Ethyl 3,4,5-trihydroxybenzoate
Gallic acid ethyl ester
Phyllemblin
Nipagallin A
Progallin A
Ethylgallate
Nipa No. 48
Gallic acid, ethyl ester
Benzoic acid, 3,4,5-trihydroxy-, ethyl ester
NIPA 48
3,4,5-Trihydroxybenzoic acid ethyl ester
Ethyl-3,4,5-trihydroxybenzoate
Ethylester kyseliny gallove
NSC 402626
Ethylester kyseliny gallove [Czech]
EINECS 212-608-5
UNII-235I6UDD3L
BRN 2116014
235I6UDD3L
CHEBI:87247
NSC-402626
ETHYL GALLATE [MART.]
DTXSID2061195
4-10-00-02002 (Beilstein Handbook Reference)
ETHYL GALLATE (MART.)
ETHYL GALLATE [INCI]
DTXCID5048348
vfpfqhqnjcmnbz-uhfffaoysa-n
831-61-8
MFCD00016430
CHEMBL453196
NSC402626
Gallic acid-ethyl ester
Ethyl gallate (Standard)
Ethyl Gallate(Ethyl 3,4,5-Trihydroxybenzoate)
SCHEMBL39599
Ethyl 3,5-trihydroxybenzoate
Ethyl-3,5-trihydroxybenzoate
HY-N0525R
BCP15872
HY-N0525
BDBM50244948
s5550
STL303724
AKOS015838687
3,5-Trihydroxybenzoic acid ethyl ester
CCG-266568
FE39365
AC-11363
AC-34482
DS-17928
E313
SY033133
3,4,5-Trihydroxy-benzoic acid ethyl ester
Benzoic acid,4,5-trihydroxy-, ethyl ester
DB-056687
CS-0009060
E0854
G0016
NS00020124
Ethyl gallate, antioxidant, >=96.0% (HPLC)
EN300-8620672
Q4532976
F1905-7042
Z1255434814
6359F896-3057-40AA-81CD-5734DCE29C20