Skip to main content

Ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate

ADVERTISEMENT
Identification
Molecular formula
C15H9N3O8
CAS number
467-76-7
IUPAC name
ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate
State
State

At room temperature, ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate is typically a solid.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
299.00
Boiling point (Kelvin)
572.15
General information
Molecular weight
365.24g/mol
Molar mass
365.2410g/mol
Density
1.5600g/cm3
Appearence

Typically, this compound is a yellow to orange crystalline solid. The intensity of the color can vary slightly depending on the crystalline structure and form.

Comment on solubility

Solubility of Ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate

Ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate exhibits distinct solubility characteristics influenced by its molecular structure and functional groups. Generally, the solubility of this compound can be described as follows:

  • Polar and non-polar characteristics: The presence of the isoxazole ring and nitro groups contributes to its polar nature, which often enhances solubility in polar solvents such as water.
  • Common solvents: This compound may be more soluble in organic solvents like ethanol, methanol, and acetone due to the compatibility of its hydrophobic furyl groups with these solvents.
  • Temperature Dependence: As with many organic compounds, solubility can vary with temperature. Higher temperatures may improve the solubility of solid compounds by increasing the kinetic energy of the molecules.
  • pH Influence: The ionization of functional groups under different pH conditions can profoundly affect the solubility of the compound, making it essential to consider the pH of the solvent when assessing solubility.

Overall, understanding the solubility profile of ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate is crucial for its applications in various chemical processes and formulations. As the adage goes, "Like dissolves like," thus the interactions between the compound and the solvent greatly dictate its solubility behavior.

Interesting facts

Interesting Facts about Ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate

Ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate is a fascinating organic compound known for its diverse applications in medicinal chemistry and material sciences. Here are some intriguing aspects of this compound:

  • Synthetic Utility: This compound serves as an important intermediate in the synthesis of various pharmaceuticals. Its nitrofuran moieties make it a target for further chemical modifications.
  • Biological Activity: The isoxazole ring system is a prominent feature in many bioactive compounds. Research suggests that derivatives of this compound exhibit notable activity against certain pathogens, thus holding potential in antibiotic development.
  • Color Impact: Nitrofuran groups are associated with distinctive coloration, which can be leveraged in dye chemistry. This property could be explored in developing innovative pigments.
  • Material Science: Studies are underway examining the properties of compounds like ethyl 3,5-bis(5-nitro-2-furyl)isoxazole-4-carboxylate in polymer science, particularly for creating novel materials with enhanced properties.

In addition to its practical uses, this compound has sparked interest among chemists for its structural beauty. The unique arrangement of atoms within the isoxazole framework, paired with the electron-withdrawing nitro groups, allows for intriguing reactivity patterns. As a result, it functions as a scaffolding for various chemical explorations, making it a subject of interest in both academic and industrial research.

In the words of a noted chemist, *"The resonance structures of compounds like this reveal the subtle interplay between stability and reactivity in organic molecules."* This statement underscores the importance of understanding complex structures and their implications in chemistry.

Synonyms
22996-55-0
4-ISOXAZOLECARBOXYLIC ACID, 3,5-BIS(5-NITRO-2-FURYL)-, ETHYL ESTER
3,5-Bis(5-nitro-2-furyl)-4-isoxazolecarboxylic acid ethyl ester
DTXSID50177539