Skip to main content

pyrimethamine hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C12H16ClN5O2
CAS number
58-14-0
IUPAC name
ethyl 4-[2,4-diamino-6-[(3-anilino-2-chloro-propyl)amino]pyrimidin-5-yl]azobenzoate;hydrochloride
State
State

Pyrimethamine hydrochloride is typically in a solid state at room temperature.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.00
Boiling point (Celsius)
153.00
Boiling point (Kelvin)
426.00
General information
Molecular weight
307.75g/mol
Molar mass
307.7460g/mol
Density
1.4500g/cm3
Appearence

Pyrimethamine hydrochloride appears as a pale to light yellow crystalline powder.

Comment on solubility

Solubility of Ethyl 4-[2,4-Diamino-6-[(3-anilino-2-chloro-propyl)amino]pyrimidin-5-yl]azobenzoate; Hydrochloride

The solubility of the compound ethyl 4-[2,4-diamino-6-[(3-anilino-2-chloro-propyl)amino]pyrimidin-5-yl]azobenzoate; hydrochloride (C12H16ClN5O2) is notably influenced by its molecular structure and the presence of functional groups. When discussing solubility, it is essential to consider the following factors:

  • Polarity: This compound has both polar and non-polar regions due to the presence of amino groups and aromatic systems. This characteristic suggests variable solubility in different solvents.
  • Hydrochloride Salt Formation: As a hydrochloride salt, this compound is likely to exhibit enhanced solubility in polar solvents such as water, compared to its base form.
  • Hydrogen Bonding: The presence of amino groups can lead to hydrogen bonding with solvent molecules, thereby increasing solubility.
  • Solvent Choice: While the compound may dissolve well in aqueous solutions, it may show reduced solubility in organic solvents due to steric hindrance and intermolecular interactions.

In conclusion, the solubility of this compound can be characterized as predominantly dependent on the solvent used, with a tendency for increased solubility in polar environments. As quoted from solubility theory, "Like dissolves like" can indeed be applied here.

Interesting facts

Ethyl 4-[2,4-Diamino-6-[(3-anilino-2-chloro-propyl)amino]pyrimidin-5-yl]azobenzoate; Hydrochloride

This fascinating compound, known for its complex structure and potential applications, is a derivative of azobenzoic acid. Here are some intriguing aspects about this molecular entity:

  • Pharmaceutical Relevance: This compound can be categorized within the larger group of azo compounds, which have been extensively studied for their *pharmaceutical properties*. Many azo compounds exhibit significant biological activity, making them of interest in drug discovery.
  • Structural Complexity: The presence of a pyrimidine ring and an amino group indicates that this compound could engage in *various interactions* within biological systems. The structural elements may allow it to act as both a substrate and an inhibitor in enzymatic reactions.
  • Chlorinated Features: The incorporation of a chlorine atom introduces special *reactivity characteristics* that could impact the compound's behavior in biochemical pathways, potentially enhancing its medicinal properties.
  • Potential as a Targeted Therapy: Compounds with such intricate structures are often tailored for targeted therapies, particularly in oncology. Their ability to interact selectively with proteins involved in disease progression could lead to innovative treatment solutions.
  • Interdisciplinary Importance: This compound is a testament to the interplay between *chemistry, pharmacology, and medicinal research*. Understanding its synthesis and behavior can pave the way for advancements in these fields.

Overall, the study of this compound may unveil new pathways for therapeutic interventions, making it a remarkable subject for both chemists and medical researchers alike. Such compounds remind us of the intricate tapestry of molecular interactions that drive biological processes.

Synonyms
10554-09-3
Benzoic acid, 4-((2,4-diamino-6-(3-anilino-2-chloro)propylamino)pyrimidin-5-yl)azo-, ethyl ester, hydrochloride