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Ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate

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Identification
Molecular formula
C19H17N3O3
CAS number
40336-66-7
IUPAC name
ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate
State
State

At room temperature, Ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate is typically in a solid state. It is often stable under normal laboratory conditions and is used in scientific research contexts as a chemical intermediate or for analytical purposes.

Melting point (Celsius)
236.50
Melting point (Kelvin)
509.65
Boiling point (Celsius)
479.50
Boiling point (Kelvin)
752.65
General information
Molecular weight
337.37g/mol
Molar mass
337.3650g/mol
Density
1.2550g/cm3
Appearence

Ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate is typically found as a crystalline solid. Its color may vary, but it generally appears as a pale yellow or light tan powder, which is consistent with many compounds containing aromatic and hetero-aromatic rings.

Comment on solubility

Solubility of Ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate

The solubility of ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate can be influenced by various factors. Due to its complex structure, this compound may exhibit specific solubility characteristics in different solvents. Here are some key points regarding its solubility:

  • Polar Solvents: The presence of polar functional groups may enhance solubility in polar solvents, such as water and methanol, albeit to a limited extent.
  • Non-Polar Solvents: It is likely to be more soluble in non-polar solvents like hexane or toluene, given its hydrophobic phenyl groups.
  • pH Dependence: The solubility could also vary with pH, potentially leading to better solubility in acidic or basic conditions depending on ionization of the amino groups.
  • Temperature Effects: Increased temperature generally leads to increased solubility, a feature that may apply to this compound as well.

In conclusion, while ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate may present challenges in terms of solubility, its polymorphic nature and functional groups offer interesting avenues for different solvation scenarios. Further experimental data would ideally provide a more comprehensive understanding of its solubility profile.

Interesting facts

Interesting Facts about Ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate

This compound is a member of the pyrazole family and has garnered attention for its versatile applications in various scientific fields. Here are some noteworthy aspects:

  • Pharmaceutical Potential: Ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate exhibits promising properties that make it a candidate for therapeutic exploration. Studies have shown that compounds within the pyrazole framework often display anti-inflammatory and analgesic activities.
  • Innovative Synthesis: The synthesis of this compound involves intricate organic chemistry techniques. Researchers employ methods such as condensation reactions and the use of various catalysts to achieve high yields and purity. This points to the importance of creativity and precision in synthetic chemistry.
  • Structural Significance: The unique structure featuring the pyrazole moiety enhances the compound's reactivity and interactions with biological targets. The 5-methyl and 2-phenyl substitutions contribute to its distinct characteristics, making it a focal point for studies related to structure-activity relationships (SAR).
  • Research Applications: Beyond pharmaceuticals, this compound also finds its way into materials science and agrochemicals. Its ability to interact with various biological systems opens doors for the development of new materials with specific functions.
  • Future Perspectives: As scientists continue to discover more about this compound, it is likely that further studies will unveil additional applications, including potential roles in drug development and disease treatment.

In summary, ethyl 4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyleneamino]benzoate stands as an intriguing compound within the realm of chemistry, offering a blend of structural uniqueness and potential applicability across multiple disciplines. As we continue to explore its properties, the future may hold exciting surprises in its journey through scientific inquiry.

Synonyms
BRN 0698003
24664-52-6
p-((3-Methyl-5-oxo-1-phenyl-2-pyrazolin-4-ylidene)methylamino)benzoic acid ethyl ester
Benzoic acid, p-((3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-ylidene)methylamino)-, ethyl ester
STK587609
AKOS005510583
ethyl 4-{[(E)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl]amino}benzoate