Skip to main content

Ethyl 4-benzoylisoxazole-3-carboxylate

ADVERTISEMENT
Identification
Molecular formula
C13H11NO4
CAS number
108385-44-2
IUPAC name
ethyl 4-benzoylisoxazole-3-carboxylate
State
State

At room temperature, ethyl 4-benzoylisoxazole-3-carboxylate is a solid.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.00
Boiling point (Celsius)
353.00
Boiling point (Kelvin)
626.00
General information
Molecular weight
259.25g/mol
Molar mass
259.2450g/mol
Density
1.2340g/cm3
Appearence

Ethyl 4-benzoylisoxazole-3-carboxylate appears as a crystalline solid. It is typically light yellow to off-white in color.

Comment on solubility

Solubility of Ethyl 4-benzoylisoxazole-3-carboxylate

Ethyl 4-benzoylisoxazole-3-carboxylate is known for its distinct solubility characteristics, which can vary significantly depending on the solvent used. Here are some key points regarding its solubility:

  • Solvent Polarities: This compound displays higher solubility in polar organic solvents such as ethanol and methanol due to the presence of polar functional groups within its structure.
  • Aqueous Solubility: It typically has limited solubility in water, which is a common characteristic for many organic compounds, leading to the need for organic solvents in various applications.
  • Temperature Effects: Solubility can also improve with an increase in temperature, making techniques like heating a practical approach to enhance dissolution in suitable solvents.

Overall, understanding the solubility of this compound is essential for its effective use in various chemical reactions and formulations. As a rule of thumb, using solvents with matching polarities often yields the best results.

Interesting facts

Exploring Ethyl 4-Benzoylisoxazole-3-Carboxylate

Ethyl 4-benzoylisoxazole-3-carboxylate, a compound with intriguing properties, is notable in the realm of organic chemistry. This compound, which falls under the category of isoxazole derivatives, has garnered attention for its potential applications.

Key Features:

  • Versatility: Compounds like ethyl 4-benzoylisoxazole-3-carboxylate serve as versatile intermediates in organic synthesis. They can be utilized to construct more complex molecules.
  • Biological Activity: There is ongoing research into the biological activities of isoxazole derivatives. Some studies suggest they may exhibit anti-inflammatory, antibacterial, and even anticancer properties.
  • Synthetic Approaches: The synthesis of this compound involves innovative chemical transformations that challenge and intrigue organic chemists. Various methods, such as cyclization reactions, demonstrate the creativity required in synthetic organic chemistry.

This compound's structure exemplifies the richness of chemical diversity, showcasing how slight modifications can lead to significant changes in properties and functionalities. As one researcher noted, "The exploration of heterocyclic compounds like ethyl 4-benzoylisoxazole-3-carboxylate provides insight into novel pathways for drug design and development."

Future Directions:

As research continues, ethyl 4-benzoylisoxazole-3-carboxylate may unveil further secrets, contributing to fields such as medicinal chemistry and material science. Its potential for innovation makes it a compound worth studying, as the scientific community seeks to harness its capabilities for real-world applications.

Synonyms
3-ISOXAZOLECARBOXYLIC ACID, 4-BENZOYL-, ETHYL ESTER
19688-04-1
4-Benzoyl-3-isoxazolecarboxylic acid ethyl ester
BRN 0992468
DTXSID90173353
DTXCID9095844
RefChem:280264
ethyl 4-benzoyl-1,2-oxazole-3-carboxylate
SCHEMBL5750757