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Rimonabant

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Identification
Molecular formula
C22H21Cl2N5O
CAS number
168273-06-1
IUPAC name
ethyl 4-(butylamino)-1-ethyl-6-methyl-pyrazolo[3,4-b]pyridine-5-carboxylate
State
State

At room temperature, Rimonabant is in a solid state. It is used primarily in experimental settings and is known to be stable under normal conditions.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
487.15
Boiling point (Kelvin)
760.30
General information
Molecular weight
462.58g/mol
Molar mass
462.5790g/mol
Density
1.2000g/cm3
Appearence

Rimonabant is typically a white to off-white solid crystalline powder. It may appear in finely divided particulate form.

Comment on solubility

Solubility of Ethyl 4-(butylamino)-1-ethyl-6-methyl-pyrazolo[3,4-b]pyridine-5-carboxylate

The solubility of ethyl 4-(butylamino)-1-ethyl-6-methyl-pyrazolo[3,4-b]pyridine-5-carboxylate, with the chemical formula C22H21Cl2N5O, can be noted for its distinctive characteristics, influenced significantly by its structural components. Understanding the solubility of such a complex organic compound involves considering several factors:

  • Polarity: This compound exhibits moderate polarity due to the presence of both hydrophobic (butyl groups) and hydrophilic (carboxylate group) elements. This balance impacts its solubility in various solvents.
  • Solvent Interaction: The solubility is likely to be better in polar solvents such as alcohols and DMSO, while being less soluble in non-polar solvents like hexane.
  • Hydrogen Bonding: The capability to form hydrogen bonds with solvents can enhance solubility, particularly with polar solvents. The carboxylate group contributes significantly to this potential.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature. Therefore, heating the solution could potentially improve its dissolution rate.

In practical terms, it can be summarized that this compound is likely to demonstrate:

  • Higher solubility in polar solvents
  • Lower solubility in non-polar environments
  • Variable solubility influenced by temperature adjustments

In conclusion, the solubility of ethyl 4-(butylamino)-1-ethyl-6-methyl-pyrazolo[3,4-b]pyridine-5-carboxylate is a nuanced trait governed by its chemical structure and the nature of the solvent. This highlights the importance of solvent choice in applications involving this compound.

Interesting facts

Interesting Facts about Ethyl 4-(Butylamino)-1-Ethyl-6-Methyl-Pyrazolo[3,4-b]Pyridine-5-Carboxylate

This compound belongs to the family of pyrazolopyridines, which are notable for their diverse biological activities. Here are some compelling insights into this fascinating compound:

  • Pharmacological Potential: Many compounds in this class exhibit pharmacological properties, making them candidates for drug development. Research in this area highlights their potential in treating various diseases, particularly in the fields of oncology and neurology.
  • Structure Activity Relationship (SAR): The structural diversity of pyrazolo derivatives, including the presence of the butylamino group, offers a unique platform to study SAR and optimize the compound's efficacy and stability.
  • Synthetic Pathways: The synthesis of this compound involves multi-step reactions that can incorporate various substitute groups, allowing for tailored modifications to enhance specific properties.
  • Biological Mechanisms: Compounds with similar structures often interact with specific receptors or enzymes in the body, making the study of their mechanism of action crucial for future therapeutic applications.
  • Emerging Research: Recent studies suggest that derivatives of this compound may play roles in various cellular processes, contributing to advancements in medicinal chemistry.

As emphasized by researchers, "Understanding the intricacies of such compounds not only unveils their therapeutic promise but also enriches our comprehension of chemical interactions at a molecular level." The exploration of such complex molecules continues to be a captivating frontier in contemporary chemistry.

In conclusion, ethyl 4-(butylamino)-1-ethyl-6-methyl-pyrazolo[3,4-b]pyridine-5-carboxylate is more than just a chemical entity; it represents a myriad of possibilities in drug discovery and molecular research.

Synonyms
Tracazolate
41094-88-6
Tracazolato
ICI 136,753
ICI-136753
ICI-136,753
NH0HPL3U1T
ICI 136753
ethyl 4-(butylamino)-1-ethyl-6-methylpyrazolo[3,4-b]pyridine-5-carboxylate
ethyl 4-(butylamino)-1-ethyl-6-methyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylate
Tracazolatum
1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 4-(butylamino)-1-ethyl-6-methyl-, ethyl ester
Ethyl 4-(butylamino)-1-ethyl-6-methyl-1H-pyrazolo(3,4-b)pyridine-5-carboxylate
NCGC00015985-03
UNII-NH0HPL3U1T
Tracazolatum [INN-Latin]
Tracazolato [INN-Spanish]
Tracazolate [USAN:INN:BAN]
EINECS 255-214-9
Tocris-1558
Lopac-T-112
Prestwick0_000976
Prestwick1_000976
Prestwick2_000976
Prestwick3_000976
TRACAZOLATE [INN]
Tracazolate (USAN/INN)
TRACAZOLATE [USAN]
Lopac0_001263
BSPBio_001011
MLS000860035
CHEMBL84567
SCHEMBL114769
SPBio_002922
BPBio1_001113
GTPL5467
Tracazolate, analytical standard
DTXSID3046956
BDBM82043
CHEBI:92596
BRD4330
HMS2233P22
HMS3260E14
HMS3374A09
BCP33109
BRD-4330
CAS_5522
NSC_5522
RBA09488
Tox21_500106
CCG-205337
LP00106
SDCCGSBI-0051230.P002
4-(Butylamino)-1-ethyl-6-methyl 1H-pyrazolo[3,4b]pyridine-5-ethylcarboxylate hydrochloride
NCGC00015985-01
NCGC00015985-02
NCGC00015985-04
NCGC00015985-05
NCGC00015985-06
NCGC00025215-01
NCGC00025215-02
NCGC00260791-01
SMR000326893
CAS-41094-88-6
AB00514650
EU-0101263
NS00030921
T-112
ICI-136753;ICI 136753
D06200
Q7831126
SR-01000075239-1
BRD-K34154330-003-03-1
BRD-K34154330-003-04-9
BRD-K34154330-003-06-4
4-(Butylamino)-1-ethyl-6-methyl-1H-pyrazolo [3,4-b]pyridine-5-carboxylic acid ethyl ester
4-Butylamino-1-ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
ETHYL 4-(BUTYLAMINO)-1-ETHYL-6-METHYL-1H-PYRAZOL(3,4-B)PYRIDINE-5-CARBOXYLATE
ethyl4-(butylamino)-1-ethyl-6-methyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylate