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Ethyl 4-guanidinobenzoate

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Identification
Molecular formula
C10H13N3O2
CAS number
3166-77-0
IUPAC name
ethyl 4-guanidinobenzoate
State
State

At room temperature, Ethyl 4-guanidinobenzoate is in a solid state, typically existing as a crystalline powder. It maintains stability under standard temperature and pressure conditions, ideal for storage and handling in its solid form.

Melting point (Celsius)
141.50
Melting point (Kelvin)
414.65
Boiling point (Celsius)
337.80
Boiling point (Kelvin)
610.95
General information
Molecular weight
206.24g/mol
Molar mass
206.2350g/mol
Density
1.3000g/cm3
Appearence

Ethyl 4-guanidinobenzoate typically appears as a white to off-white crystalline powder. Its appearance can sometimes vary slightly depending on the purity and specific form it is in, but generally maintains a solid, crystalline structure at room temperature.

Comment on solubility

Solubility of Ethyl 4-Guanidinobenzoate

Ethyl 4-guanidinobenzoate, a compound commonly utilized in various chemical applications, exhibits notable solubility properties that can influence its usability. Understanding its solubility is crucial for effective application in solutions and reactions.

Solubility Characteristics:

  • Water Solubility: Generally, the solubility of ethyl 4-guanidinobenzoate in water is moderate. The presence of the guanidine functional group enhances its affinity for polar solvents, leading to reasonable dissolution in aqueous media.
  • Organic Solvents: This compound is also soluble in various organic solvents, including ethanol and methanol. This trait allows it to be effectively applied in organic synthesis and other chemical processes.
  • Temperature Influence: The solubility can vary significantly with temperature. Comparable to many organic compounds, an increase in temperature tends to enhance solubility.
  • pH Dependency: The solubility may also be affected by the pH of the solvent, owing to the basicity of the guanidine group. Therefore, solubility can improve in more acidic environments.

In summary, ethyl 4-guanidinobenzoate showcases variable solubility behavior that is essential for its application in both aqueous and organic contexts. Understanding these solubility characteristics enables chemists to effectively utilize this compound in different reactions and formulations.

Interesting facts

Interesting Facts About Ethyl 4-Guanidinobenzoate

Ethyl 4-guanidinobenzoate, a compound with intriguing biochemical applications, is noted for its role in various pharmaceutical processes. Here's what makes this compound particularly fascinating:

  • Pharmaceutical Significance: This compound is often utilized in drug synthesis, particularly for the development of antihypertensive agents. Its ability to act on the vascular system highlights its importance in cardiovascular research.
  • Structure Matters: The guanidine functional group plays a crucial role in the compound's reactivity. Its ability to donate protons makes it a potential candidate for catalysis in organic reactions.
  • Biological Activity: Ethyl 4-guanidinobenzoate has been shown to exhibit various biological activities, including inhibition of certain enzymes. This makes it a valuable tool in biochemical studies aimed at understanding metabolic pathways.
  • Research Tool: Chemists often use this compound as a model derivative in studies related to drug design, particularly investigating how modifications to the guanidino group can influence the pharmacological efficacy of related molecules.
  • Multifunctionality: Besides its application in pharmaceuticals, this compound demonstrates potential in other fields, including biochemistry and analytical chemistry, showcasing its versatility in chemical science.

In summary, ethyl 4-guanidinobenzoate is not only significant in therapeutic contexts but also serves as a critical component for experimental procedures in the study of chemical reactions and biological processes. As researchers continue to explore its properties, the compound's role in innovation may expand further, affirming its standing in the chemistry community.

Synonyms
15639-51-7
ethyl 4-(diaminomethylideneamino)benzoate
Ethyl 4-guanidinobenzoate
ethyl 4-carbamimidamidobenzoate
ETHYL 4-([AMINO(IMINO)METHYL]AMINO)BENZOATE
ETHYL 4-{[AMINO(IMINO)METHYL]AMINO}BENZOATE
ethyl p-guanidinobenzoate
SCHEMBL6339534
CHEMBL1161463
SCHEMBL24087906
DTXSID00274966
AKOS015957310
WS-02225
DB-142340
E72126
EN300-236615
ETHYL4-([AMINO(IMINO)METHYL]AMINO)BENZOATE
F2158-0689