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Methylphenidate Hydrochloride

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Identification
Molecular formula
C14H20ClNO2
CAS number
298-59-9
IUPAC name
ethyl 4-phenyl-1-(2-phenyl-2-pyrrolidin-1-ium-1-yl-ethyl)piperidin-1-ium-4-carboxylate;4-hydroxy-4-oxo-but-2-enoate
State
State

At room temperature, methylphenidate hydrochloride is in a solid state. It is a stable compound that remains solid unless exposed to conditions of extreme heat or moisture that could affect its physical form.

Melting point (Celsius)
224.00
Melting point (Kelvin)
497.00
Boiling point (Celsius)
388.00
Boiling point (Kelvin)
661.00
General information
Molecular weight
269.77g/mol
Molar mass
269.7700g/mol
Density
1.2000g/cm3
Appearence

Methylphenidate hydrochloride is commonly found as a white to off-white, odorless, crystalline powder. It may also appear as small, colorless crystals. It is often used in pharmaceutical formulations and is known for its stability and ease of handling in solid form.

Comment on solubility

Solubility of Ethyl 4-phenyl-1-(2-phenyl-2-pyrrolidin-1-ium-1-yl-ethyl)piperidin-1-ium-4-carboxylate; 4-hydroxy-4-oxo-but-2-enoate

When evaluating the solubility of the complex compound ethyl 4-phenyl-1-(2-phenyl-2-pyrrolidin-1-ium-1-yl-ethyl)piperidin-1-ium-4-carboxylate; 4-hydroxy-4-oxo-but-2-enoate, several factors need to be considered:

  • Polarity: The presence of multiple polar functional groups, including carboxylate and pyrrolidine moieties, suggests that this compound may exhibit favorable solubility in polar solvents such as water.
  • Hydrophilic vs. Hydrophobic regions: The ethyl and phenyl groups introduce hydrophobic characteristics, which could limit solubility in purely aqueous environments, indicating possible amphiphilic behavior.
  • Charge: Given that the structure contains quaternary ammonium features, it may enhance solubility in polar solvents due to ionic interactions.
  • pH sensitivity: The stability and solubility might vary with pH, particularly due to the presence of the carboxylate and oxo functional groups, indicating potential alterations in solubility under different pH conditions.
  • Temperature: Solubility may also be impacted by temperature fluctuations, with increased solubility often observed at elevated temperatures.

In summary, while definitive solubility data for this intricate compound may not be readily available, its structural characteristics imply a potential for variable solubility, contingent on solvent choice and environmental conditions. As the compound encompasses both hydrophilic and hydrophobic segments, careful experimental investigation would be essential for determining exact solubility profiles in different media.

Interesting facts

Interesting Facts about Ethyl 4-phenyl-1-(2-phenyl-2-pyrrolidin-1-ium-1-yl-ethyl)piperidin-1-ium-4-carboxylate;4-hydroxy-4-oxo-but-2-enoate

This complex compound belongs to a fascinating class of chemical entities, often studied for their potential therapeutic applications. Here are some engaging facts that highlight the significance and utility of this compound:

  • Pharmacological Potential: The intricate structure of this compound suggests potential bioactivity, especially in the realm of pharmacology. Compounds with similar configurations have been explored for their roles as neuroprotective agents and in mental health treatments.
  • Structure-Activity Relationship (SAR): The diverse functional groups present in this compound facilitate in-depth studies of SAR, allowing chemists to understand how variations in molecular structure can influence biological activity.
  • Applications in Organic Synthesis: The presence of both carboxylate and carbonyl functionalities may serve as key intermediates in various organic synthesis pathways, enabling the creation of even more complex molecules.
  • Cognitive Exploration: The pyrrolidine and piperidine rings suggest the compound may interact with neurotransmitter systems, yielding insights into cognition and behavior that are crucial for developing new treatments for mental health disorders.
  • Emerging Research: As researchers continue to explore the implications of compounds like this, a growing body of literature points to their potential in combating neurological diseases and as anti-inflammatory agents.

Overall, the chemical complexity and potential applications of this compound make it an intriguing subject of study, showcasing the multifaceted nature of organic chemistry and its implications in real-world issues.