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Ethylphenidate

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Identification
Molecular formula
C15H21NO2
CAS number
57413-43-1
IUPAC name
ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate
State
State

The compound is typically in a solid state at room temperature, appearing as a crystalline powder.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
292.50
Boiling point (Kelvin)
565.70
General information
Molecular weight
263.36g/mol
Molar mass
263.3590g/mol
Density
1.1680g/cm3
Appearence

Ethylphenidate typically appears as a white to off-white crystalline powder. Its appearance may vary slightly based on purity and form.

Comment on solubility

Solubility of Ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate

The solubility of ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate can be influenced by various factors, making it an interesting compound for study. Here are some key points to consider:

  • Polarity: The presence of the piperidine ring and the tetrahydrofuran moiety suggests a balance between polar and non-polar characteristics, which can affect solubility in different solvents.
  • Solvent Interaction: This compound may exhibit better solubility in polar aprotic solvents such as dimethyl sulfoxide (DMSO) or acetone due to its functional groups.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature, enabling better dissolution in various media.

It is often observed that compounds of this nature can also be slightly soluble in water, aided by their ability to form hydrogen bonds with water molecules. However, due to the larger non-polar structures present, complete solubility in water is likely to be limited.

As a guiding principle, the solubility of ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate:

  1. May exhibit moderately low water solubility.
  2. Could be completely soluble in organic solvents.
  3. Is influenced heavily by environmental conditions such as pH and temperature.

Overall, understanding the solubility of this compound is crucial, as it can significantly impact its bioavailability and potential applications in various fields, particularly in medicinal chemistry.

Interesting facts

Interesting Facts about Ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate

Ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate is a fascinating compound, particularly recognized for its role in medicinal chemistry and potential applications in pharmaceuticals. Here are some engaging aspects of this compound:

  • Structural Diversity: The compound features a piperidine ring which is a key fragment in many biological molecules. Its unique structure contributes to the compound's distinctive properties.
  • Potential Therapeutic Applications: Research indicates that this compound may exhibit activities that could be beneficial in treating various neurological disorders. Its ability to interact with specific neurotransmitter receptors makes it a candidate for further investigation.
  • Synthetic Routes: The synthesis of ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate involves several organic reactions, emphasizing the importance of understanding reaction mechanisms and the ability to design multi-step synthetic pathways in organic chemistry.
  • Interdisciplinary Connections: The compound is of interest not only in chemistry but also in pharmacology, biochemistry, and medicinal chemistry, showcasing how interdisciplinary approaches can lead to new discoveries in drug development.
  • Research Opportunities: As scientists continue to study its properties, there's a growing opportunity for new research in derivatization and optimization of the compound to enhance its therapeutic index and reduce potential side effects.

In summary, ethyl 4-phenyl-1-(2-tetrahydrofuran-2-ylethyl)piperidine-4-carboxylate holds promise in the realm of drug discovery with its unique structure and potential biological activities. Ongoing exploration could pave the way for innovative treatments and enhance our understanding of chemical interactions within biological systems.

Synonyms
TA 109
BRN 0436624
3542-75-4
4-Phenyl-1-(2-(tetrahydro-2-furyl)ethyl)isonipecotic acid ethyl ester
ISONIPECOTIC ACID, 4-PHENYL-1-(2-(TETRAHYDRO-2-FURYL)ETHYL)-, ETHYL ESTER
5-22-02-00494 (beilstein handbook reference)
ethyl 1-[2-(oxolan-2-yl)ethyl]-4-phenylpiperidine-4-carboxylate
DTXSID50956821