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Etodolac

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Identification
Molecular formula
C17H21NO3
CAS number
41340-25-4
IUPAC name
ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate
State
State

Etodolac is a solid at room temperature, typically found in the form of a powder.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.00
General information
Molecular weight
287.37g/mol
Molar mass
287.3710g/mol
Density
1.2000g/cm3
Appearence

Etodolac appears as a white crystalline powder. It is often marketed in the form of tablets or capsules for medical use.

Comment on solubility

Solubility of Ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate

The solubility of ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate is a topic of great interest in both scientific and practical applications. Understanding how this compound behaves in various solvents can help in the formulation of drugs, where solubility directly affects bioavailability and efficacy. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of this compound tends to vary significantly with the choice of solvent. It is likely to be more soluble in polar solvents such as water and alcohols due to the presence of functional groups capable of hydrogen bonding.
  • Temperature Influence: Like many organic compounds, the solubility may increase with temperature, allowing for greater dissolution rates in heated solvents.
  • pH Sensitivity: The solubility can also be pH-dependent, with possible increases in solubility in more alkaline or acidic environments due to ionization of the amino or carboxylate groups present.
  • Impurity Effects: The presence of impurities or co-solvents can alter the solubility profile, highlighting the importance of purity in experimental settings.

In conclusion, the solubility characteristics of ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate present a complex interplay of factors that must be considered during its use in formulations. As with many compounds, the ability to predict and manipulate solubility can lead to better performance in application.

Interesting facts

Interesting Facts about Ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate

Ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate, commonly referred to in the field for its intriguing chemical structure, is a compound that captures the imagination of both chemists and pharmacologists. Here are some engaging insights:

  • Structural Complexity: This compound features an indole core, which is a fundamental structure in numerous biologically active molecules. The incorporation of a diethylamino group suggests potential for interesting interactions with biological systems.
  • Pharmacological Potential: Compounds with indole structures often exhibit a range of biological activities, including anti-inflammatory and anticancer properties. The ethoxy and carboxylate functionalities can influence solubility and reactivity, making this compound a candidate for further investigation in medicinal chemistry.
  • Applications in Sciences: Due to its unique chemical properties, this compound could be explored in various applications such as drug design, where modifying the existing structure could enhance efficacy or reduce side effects.
  • Quote from Research: "The diverse chemistry of indole derivatives places them at the forefront of compounds worthy of exploration in pharmacological development." This emphasizes the ongoing interest in indole-containing compounds like this one.

Overall, the exploration of ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-indole-3-carboxylate not only highlights the beauty of organic synthesis but also underscores the importance of structural investigation in understanding and harnessing chemical potential.

Synonyms
Oprea1_511595
HMS3433E13
AKOS000511264
CCG-125058
ST008170
EU-0051821
SR-01000519326
SR-01000519326-1
ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethylindole-3-carboxylate
ethyl 5-[2-(diethylamino)ethoxy]-1,2-dimethyl-1H-indole-3-carboxylate