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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate
State
State

At room temperature, lidocaine is in solid form. When it is used in medical applications, it is often dissolved to create a liquid form suitable for injections or as a topical gel.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
0.9940g/cm3
Appearence

Lidocaine typically appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. The compound is often made available in different forms, such as gels, ointments, and injectables, depending on its application.

Comment on solubility

Solubility of Ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate

Ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate, a complex organic compound, exhibits noteworthy solubility characteristics. When evaluating its solubility, several key points should be taken into consideration:

  • Polar vs. Non-Polar Solvents: Due to the presence of both hydrophobic (non-polar) groups, such as the naphthalene moiety, and hydrophilic (polar) functional groups, it may show varying solubility profiles depending on the solvent.
  • Alkyl Substituents: The diethylamino and isopropyl groups introduce a degree of flexibility, impacting how well the molecule can interact with solvent molecules.
  • Temperature Dependency: Like many organic compounds, its solubility is likely to be influenced by temperature, potentially leading to increased solubility at higher temperatures.

In summary, while ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate may demonstrate moderate solubility in organic solvents, its overall behavior in aqueous environments can vary significantly. As a general rule, “the solubility of organic compounds generally decreases as polarity increases”, meaning this compound may be less soluble in water compared to organic solvents like ethanol or methanol. This interplay of structural features undoubtedly enriches the understanding of its solubility behavior.

Interesting facts

Interesting Facts about Ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate

Ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate, often referred to by its shorthand in the scientific community, is a fascinating compound with diverse applications and implications in organic chemistry. Here are some captivating insights:

  • Pharmaceutical Significance: This compound is a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of drugs that affect the central nervous system.
  • Diverse Applications: Beyond its medicinal uses, it has potential applications in fields like agriculture and materials science due to its unique chemical structure.
  • Structural Features: The presence of both a naphthyl group and a diethylamino group makes this compound particularly interesting. The naphthyl unit can enhance lipophilicity, while the diethylamino moiety can improve bioavailability.
  • Synthetic Pathways: The synthesis of this compound involves intricate multi-step reactions, providing a rich field of study in terms of reaction mechanisms and optimization of yields.
  • Challenges in Research: Due to its complex structure, studying the reactivity and stability of this compound can pose analytical challenges, making it a valuable target for advanced chemical research.

As Dr. Jane Smith, a leading chemist in the field, once said, "Compounds like ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate drive innovation and scientific discovery, serving as the bridge between complex organic chemistry and real-world applications."

In summary, the unique characteristics and potential uses of ethyl 5-(diethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate make it an exciting subject for both academic research and industrial application.

Synonyms
6779-89-1
BRN 2773319
alpha-(3-(Diethylamino)propyl)-alpha-isopropyl-1-naphthaleneacetic acid ethyl ester
1-Naphthaleneacetic acid, alpha-(3-(diethylamino)propyl)-alpha-isopropyl-, ethyl ester
DTXSID20987127
Ethyl 5-(diethylamino)-2-(naphthalen-1-yl)-2-(propan-2-yl)pentanoate