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Lidocaine

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Identification
Molecular formula
C21H32N2O2
CAS number
137-58-6
IUPAC name
ethyl 5-(dimethylamino)-2-[3-(dimethylamino)propyl]-2-(1-naphthyl)pentanoate
State
State
Lidocaine is a solid at room temperature, often supplied in a crystalline form that is suitable for various pharmaceutical applications.
Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
324.47g/mol
Molar mass
324.4690g/mol
Density
1.0140g/cm3
Appearence

Lidocaine typically appears as a white crystalline powder. It is odorless and has a slightly bitter taste. This compound is known for its characteristic crystalline structure and can be dissolved in water and alcohol, which are commonly used solvents for its applications.

Comment on solubility

Solubility of Ethyl 5-(Dimethylamino)-2-[3-(Dimethylamino)propyl]-2-(1-naphthyl)pentanoate

The solubility of ethyl 5-(dimethylamino)-2-[3-(dimethylamino)propyl]-2-(1-naphthyl)pentanoate can be characterized by several key factors:

  • Polar and Nonpolar Interactions: This compound contains both polar and nonpolar functional groups, which suggests a potential for varied solubility in different solvents. The presence of the dimethylamino groups indicates some level of polarity, which may enhance solubility in polar solvents such as water and alcohols.
  • Hydrophobic Character: The naphthyl group and the long alkyl chains in the structure impart significant hydrophobic characteristics. This feature often leads to poor solubility in highly polar solvents, favoring solubility in organic solvents like ethanol, methanol, or dichloromethane.
  • Temperature Impact: Like many organic compounds, the solubility of this substance is likely to increase with temperature. Increased kinetic energy helps to disrupt intermolecular forces.
  • pH Influence: Since the compound carries amine groups, its solubility could be affected by pH changes in solution, potentially becoming more soluble in acidic environments where protonation occurs.

Ultimately, the solubility of this compound is a balance of its structural components and the solvent's properties. Experimentation would provide the most accurate solubility profile, allowing for a practical understanding of its behavior in various chemical environments.

Interesting facts

Interesting Facts about Ethyl 5-(dimethylamino)-2-[3-(dimethylamino)propyl]-2-(1-naphthyl)pentanoate

Ethyl 5-(dimethylamino)-2-[3-(dimethylamino)propyl]-2-(1-naphthyl)pentanoate is a fascinating compound with significant implications in various scientific fields. Here are some intriguing insights:

  • Pharmacological Potential: This compound is part of a class of molecules often investigated for their potential pharmaceutical applications, particularly in the realm of psychopharmacology due to its amine functional groups.
  • Chemical Structure: The presence of branched alkyl groups and aromatic naphthalene structures contributes to its lipophilicity, which might influence its interactions with biological membranes and receptors.
  • Research Opportunities: Chemists and pharmacologists often explore such compounds for their effects on neurotransmitter systems, offering pathways to develop new therapeutic agents.
  • Synthesis Complexity: The synthesis of this compound typically requires meticulous planning and expertise in organic synthesis techniques, often involving multiple reaction steps to acquire the desired structure.
  • Analytical Methods: Characterization of this compound often employs techniques such as nuclear magnetic resonance (NMR) and mass spectrometry, showcasing the advancements in analytical chemistry.

In summary, ethyl 5-(dimethylamino)-2-[3-(dimethylamino)propyl]-2-(1-naphthyl)pentanoate stands as a testament to the intricate interplay between chemistry and biology, opening doors to new discoveries that could reshape our understanding of drug development and therapeutic interventions.

Synonyms
14722-16-8
BRN 2777831
1-NAPHTHALENEACETIC ACID, alpha,alpha-BIS(3-(DIMETHYLAMINO)PROPYL)-, ETHYL ESTER
DTXSID40163628
alpha,alpha-Bis(3-(dimethylamino)propyl)-1-naphthaleneacetic acid ethyl ester
alpha,alpha-Bis[3-(dimethylamino)propyl]-1-naphthaleneacetic acid ethyl ester
DTXCID2086119
ethyl 5-(dimethylamino)-2-[3-(dimethylamino)propyl]-2-naphthalen-1-ylpentanoate