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Ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate

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Identification
Molecular formula
C12H10N2O6
CAS number
2179-54-8
IUPAC name
ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate
State
State

At room temperature, ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is found in a solid state. It remains stable under standard conditions, provided it is stored in a suitable environment to prevent degradation.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
279.24g/mol
Molar mass
279.2350g/mol
Density
1.3400g/cm3
Appearence

Ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate typically appears as a yellow crystalline solid. It may present fine or powdery texture depending on the preparation and processing methods used.

Comment on solubility

Solubility of Ethyl 5-Methyl-3-(5-Nitro-2-Furyl)Isoxazole-4-Carboxylate

Ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate, with its complex structure, presents unique challenges and characteristics regarding its solubility. Understanding its solubility is essential for its applications and effectiveness in various chemical processes.

Factors Influencing Solubility:

  • Polarity: The nitro group and the carboxylate moiety highly influence the molecule's polarity, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules may increase solubility, especially in protic solvents.
  • Aggregate Formation: The tendency to form dimers or other aggregates can affect solubility, often reducing it in non-polar solvents.

Predicted Solubility Behavior:

This compound is likely to be:

  • Soluble in polar organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).
  • Less soluble in non-polar solvents due to its functional groups that do not interact favorably with non-polar environments.

In summary, the solubility of ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is significantly influenced by its functional groups and molecular interactions. Understanding these solubility characteristics is crucial for optimizing its use in chemical and pharmaceutical applications.

Interesting facts

Interesting Facts about Ethyl 5-Methyl-3-(5-Nitro-2-Furyl)isoxazole-4-carboxylate

Ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate is a compound that merges both medicinal and synthetic chemistry realms. Here are some engaging insights about this intriguing compound:

  • Structural Elegance: The structure of this compound includes an isoxazole ring, which is a five-membered heterocyclic compound featuring nitrogen and oxygen. This unique feature often enhances the compound's pharmacological properties.
  • Pharmaceutical Potential: This compound has been explored in various studies for its potential as a pharmaceutical agent, especially in areas dealing with anti-inflammatory and antimicrobial effects.
  • Furyl Linkage: The 5-nitro-2-furyl group is particularly interesting, as it can influence the biological activity of the compound. Furans are known for their roles in various bioactive molecules, leading to numerous applications in medicinal chemistry.
  • Versatile Synthesis: The synthesis of ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate can be achieved through different synthetic pathways, showcasing the versatility of modern organic synthesis techniques. Researchers often tweak reaction conditions to optimize yields and purity.
  • Research & Development: Continuous research surrounding this compound is crucial. Scientists investigate its interaction with biological targets, exploring structure-activity relationships (SAR) while aiming to enhance its therapeutic efficacy.
  • Interdisciplinary Connections: This compound exhibits connections to fields such as pharmacognosy and materials science, encouraging collaboration among chemists, biologists, and pharmacologists to unveil further insights.

As we continue to explore the capabilities of ethyl 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxylate, we may uncover new pathways for drug development and expanded applications in the chemical sciences.

Synonyms
4-ISOXAZOLECARBOXYLIC ACID, 5-METHYL-3-(5-NITRO-2-FURYL)-, ETHYL ESTER
17960-18-8
BRN 0555751
5-Methyl-3-(5-nitro-2-furyl)-4-isoxazolecarboxylic acid ethyl ester
DTXSID70170840