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Ethyl aziridine-1-carboxylate

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Identification
Molecular formula
C5H9NO2
CAS number
5766-56-5
IUPAC name
ethyl aziridine-1-carboxylate
State
State

Ethyl aziridine-1-carboxylate is in a liquid state at room temperature. It exhibits fluidic properties typical of organic liquids and is volatile. It should be handled carefully under appropriate laboratory conditions to ensure safety.

Melting point (Celsius)
-39.00
Melting point (Kelvin)
234.15
Boiling point (Celsius)
111.00
Boiling point (Kelvin)
384.15
General information
Molecular weight
115.15g/mol
Molar mass
115.1450g/mol
Density
0.9370g/cm3
Appearence

Ethyl aziridine-1-carboxylate is a colorless to pale yellow liquid with a characteristic amine-like odor. It is typically observed in laboratories in its liquid form, and the appearance can vary slightly depending on the concentration and specific conditions it is in.

Comment on solubility

Solubility of Ethyl Aziridine-1-carboxylate

Ethyl aziridine-1-carboxylate, a compound with intriguing chemical properties, exhibits a distinctive solubility profile that can be influenced by various factors. Understanding its solubility is essential for applications in organic synthesis and drug design.

Key Solubility Characteristics:

  • Polarity: The presence of both an ether and a carboxylate functional group generally imparts moderate polarity to ethyl aziridine-1-carboxylate, facilitating its ability to interact with polar solvents.
  • Solvent Interaction: It is expected to be soluble in polar aprotic solvents such as acetone, dimethyl sulfoxide (DMSO), and ethanol due to favorable dipole interactions.
  • Water Solubility: While the compound may show limited solubility in water, the extent can vary based on the pH and temperature of the solution.
  • Temperature Effects: Increasing the temperature often enhances solubility; therefore, testing solubility at elevated temperatures can provide improved results.

In summary, the solubility of ethyl aziridine-1-carboxylate is influenced by its molecular structure and the choice of solvent. As a rough guideline, it tends to dissolve well in polar solvents while showing varying degrees of solubility in water under different conditions.

Interesting facts

Interesting Facts About Ethyl Aziridine-1-Carboxylate

Ethyl aziridine-1-carboxylate is a fascinating compound, especially noted for its unique structure and potential applications in various fields of chemistry. Here are some intriguing aspects:

  • Structural Uniqueness: The aziridine ring is a three-membered cyclic amine, which imparts distinct reactivity and properties compared to more common ring systems like cyclohexane. This structural configuration often leads to interesting reaction pathways.
  • Synthesis Versatility: Ethyl aziridine-1-carboxylate can be synthesized through various methods, showcasing the creativity of chemists. One common approach involves the reaction of ethyl acrylate with aziridine derivatives, which allows for modifications depending on desired functional groups.
  • Biological Relevance: Compounds featuring aziridine rings are significant in medicinal chemistry. Ethyl aziridine-1-carboxylate is studied for its potential in drug development due to its interactions with biological targets, potentially leading to novel therapeutics.
  • Applications Beyond Medicine: Beyond medicinal uses, this compound has potential applications in materials science, particularly in creating polymers with unique properties. Its reactivity can be advantageous in designing materials with specific characteristics.
  • Reactivity and Mechanisms: The presence of both the aziridine and carboxylate groups makes this compound particularly interesting in terms of reactivity. It may participate in a variety of reactions including nucleophilic substitutions and cycloadditions, which are essential in organic synthesis.

In summary, ethyl aziridine-1-carboxylate is not just a simple compound; it embodies a rich area of exploration for chemists looking to develop new materials and pharmaceuticals. As one noted chemist said, "The magic of chemistry lies not just in the compounds we study, but in the endless possibilities they present."

Synonyms
671-51-2
ethyl aziridine-1-carboxylate
N-(Ethoxycarbonyl)aziridine
N-Carbethoxyethylenimine
N-Ethoxycarbonylethylenimine
Ethyl 1-aziridinecarboxylate
Ethyl aziridinylformate
N-Ethoxycarbonylethyleneimine
Ethyl 1-aziridinylcarboxylate
1-Ethoxycarbonylaziridine
Ethyl aziridinecarboxylate
Ethyl aziridinocarboxylate
Ethoxycarbonyl-1-ethylenimine
Aziridinecarboxylic acid, ethyl ester
1-AZIRIDINECARBOXYLIC ACID, ETHYL ESTER
AI3-60257
Carbamic acid, N,N-ethylene-, ethyl ester
T577P56NRQ
NSC-26962
N,N-Ethyleneurethane
NSC 26962
BRN 0110143
ethoxycarbonylaziridine
WLN: T3NTJ AVO2
ethylaziridine-1-carboxylate
UNII-T577P56NRQ
Ethoxycarbonylethylenimine, N-
SCHEMBL1684895
DTXSID10217405
NSC26962
1-Aziridinecarboxylicacid ethyl ester
Carbamic acid,N-ethylene-, ethyl ester
DB-250275