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Etedronate

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Identification
Molecular formula
C17H26N2O2
CAS number
104876-72-6
IUPAC name
ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate
State
State

At room temperature, ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate typically exists as a solid. It’s often utilized in fine chemical synthesis and pharmaceutical research due to its stability.

Melting point (Celsius)
114.50
Melting point (Kelvin)
387.70
Boiling point (Celsius)
470.30
Boiling point (Kelvin)
743.50
General information
Molecular weight
322.41g/mol
Molar mass
322.4140g/mol
Density
1.1140g/cm3
Appearence

Ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate appears as a crystalline solid. It may be colorless to pale yellow, depending on conditions and purity. The compound forms are quite stable under normal laboratory conditions.

Comment on solubility

Solubility of Ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate

The solubility of ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate can be quite intriguing given its molecular structure. Solubility is crucial for understanding the compound's behavior in various environments, especially in biological systems. Key points to consider include:

  • Polar vs. Non-Polar: Due to its ethyl and carbamate groups, the compound features both polar and non-polar characteristics, which influences its solubility in different solvents.
  • Solvent Compatibility: Ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate is more likely to be soluble in organic solvents such as ethanol, DMSO (dimethyl sulfoxide), and chloroform, compared to water.
  • Hydrogen Bonding: The carbamate functional group can participate in hydrogen bonding, potentially enhancing solubility in polar solvents, albeit typically to a limited extent.
  • Temperature Effects: As is common in many organic compounds, solubility may increase with temperature, making it important to consider thermal conditions in experimental setups.

In summary, while ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate may exhibit moderate solubility characteristics, it is essential to assess the specific solvent system and temperature when evaluating its dissolution behavior. Understanding these solubility traits is critical in pharmaceutical applications, where solubility can significantly affect bioavailability.

Interesting facts

Interesting Facts about Ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate

Ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate is a fascinating compound that belongs to the class of carbamates, which are known for their diverse applications in both medicine and agriculture. This compound specifically stands out due to its unique structural features and potential biological activities.

Key Characteristics:

  • Therapeutic Applications: Compounds based on the piperazine structure are often explored for their psychoactive properties and are used in the development of drugs that target neurological disorders.
  • Antimicrobial Properties: Some studies have hinted that derivatives like ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate may exhibit antimicrobial effects, making them potential candidates in the fight against resistant bacteria.
  • Structural Insights: The presence of the piperazine ring contributes to the compound's biological reactivity, emphasizing how slight changes in molecular structure can lead to significantly different biological activities.

As a chemist, it’s particularly exciting to observe how synthetic modifications to basic frameworks, like piperazine, can lead to an array of compounds with varying pharmacological profiles. This reminds us that in chemistry, the art of synthesis is as important as understanding structure-activity relationships.

Did You Know?

The development of carbamates can be traced back to the 19th century, and they have evolved significantly in their applications. Today, they are not just limited to pharmaceuticals but are also pivotal in the production of pesticides and herbicides.

In summary, ethyl N-[2-(4-benzylpiperazin-1-yl)ethyl]carbamate exemplifies the innovative spirit of modern chemistry, bridging the gap between synthetic design and practical application. As research continues, who knows what new revelations may arise from this compound?

Synonyms
23111-68-4
BRN 0826239
CARBAMIC ACID, (2-(4-BENZYL-1-PIPERAZINYL)ETHYL)-, ETHYL ESTER
1-(2-Carbaethoxaminoaethyl)-4-benzylpiperazin [German]
1-(2-Carbaethoxaminoaethyl)-4-benzylpiperazin
DTXSID90177679
5-23-01-00295 (Beilstein Handbook Reference)
RefChem:331848
DTXCID00100170