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Chlorphenamine

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Identification
Molecular formula
C20H25ClN2O
CAS number
132-22-9
IUPAC name
ethyl N-[4-[4-[2-(diethylamino)ethyl]piperazin-4-ium-1-yl]butyl]carbamate;chloride
State
State
The compound is generally solid at room temperature, appearing as a crystalline powder.
Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
368.88g/mol
Molar mass
368.3200g/mol
Density
1.0900g/cm3
Appearence

Chlorphenamine is typically found as a white to off-white crystalline powder. It is odorless or has a very slight odor.

Comment on solubility

Solubility of Ethyl N-[4-[4-[2-(diethylamino)ethyl]piperazin-4-ium-1-yl]butyl]carbamate; Chloride

Ethyl N-[4-[4-[2-(diethylamino)ethyl]piperazin-4-ium-1-yl]butyl]carbamate; chloride is classified as a quaternary ammonium compound, which often exhibits interesting solubility characteristics. The solubility of this compound can be evaluated based on various factors:

  • Polarity: Due to the presence of multiple polar functional groups, this compound is likely to be soluble in polar solvents such as water.
  • Ionic Nature: As it is a chloride salt, it typically has good solubility in aqueous environments. This ionic characteristic helps the compound dissociate in solution.
  • Hydrogen Bonding: With the functional groups available, the potential for hydrogen bonding further enhances solubility in suitable solvents.
  • Temperature Influence: Solubility can be temperature-dependent, with increased temperatures generally resulting in greater solubility for ionic compounds.

It is important to note that, although the compound is likely to exhibit good solubility in solvents with a high dielectric constant, compounds with hydrophobic regions may potentially limit solubility in nonpolar solvents. Therefore, one might say:

"The solubility of ethyl N-[4-[4-[2-(diethylamino)ethyl]piperazin-4-ium-1-yl]butyl]carbamate; chloride is facilitated by its ionic properties and polar nature, making it ideally suited for polar solvents."

In practical applications, knowledge of solubility behavior is crucial for tasks such as formulation development, drug delivery, and environmental modeling, allowing chemists to predict interactions and stability in a given medium.

Interesting facts

Interesting Facts about Ethyl N-[4-[4-[2-(diethylamino)ethyl]piperazin-4-ium-1-yl]butyl]carbamate;chloride

The compound we are discussing is a fascinating and complex molecule with significant implications in the fields of medicinal chemistry and pharmacology. Here are some interesting highlights about this compound:

  • Pharmaceutical Relevance: This compound is often investigated for its potential applications in drug development, especially in areas related to neurology and psychiatry.
  • Quaternary Ammonium Structure: The presence of the diethylamino and piperazine moieties suggests that this compound may exhibit quaternary ammonium characteristics, which are known to influence its interaction with biological membranes.
  • Carbamate Group: The carbamate functional group is recognized for its role in various biological processes, and its similarity to the structure of neurotransmitters makes this compound an interesting candidate for studying neurotransmission.
  • Ion Transport: As a chloride salt, this compound may play a role in facilitating ion transport across cellular membranes, further emphasizing its importance in pharmacological studies.
  • Potential Side Effects: While investigating new pharmaceuticals, it is essential to consider not only the therapeutic effects but also any possible side effects associated with this compound, as they could arise from its complex structure.

In summary, ethyl N-[4-[4-[2-(diethylamino)ethyl]piperazin-4-ium-1-yl]butyl]carbamate;chloride represents a significant area of research interest, embodying the intricate relationship between chemical structure and biological activity. It serves as a reminder of how small changes in molecular architecture can have profound effects on drug efficacy and safety.

Synonyms
Carbamic acid, (4-(4-(2-(diethylamino)ethyl)-1-piperazinyl)butyl)-, ethyl ester, hydrochloride
(4-(4-(2-(Diethylamino)ethyl)-1-piperazinyl)butyl)carbamic acid ethyl ester hydrochloride
24280-44-2
RefChem:332093