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ethazol

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Identification
Molecular formula
C11H12N4O2 · HCl
CAS number
2846-71-5
IUPAC name
ethyl N-(phthalazin-1-ylamino)carbamate;hydrochloride
State
State

This compound is typically found in a solid state at room temperature.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.00
Boiling point (Celsius)
384.00
Boiling point (Kelvin)
657.00
General information
Molecular weight
282.71g/mol
Molar mass
282.7050g/mol
Density
1.4000g/cm3
Appearence

It is a white to off-white crystalline powder, often supplied as a hydrochloride salt for increased solubility and stability.

Comment on solubility

Solubility of Ethyl N-(phthalazin-1-ylamino)carbamate Hydrochloride

The solubility of ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride is a crucial aspect of its chemical behavior and applications. Understanding its solubility can provide insights into its potential uses in various formulations and reactions. Here are some key points:

  • Water Solubility: This compound exhibits moderate solubility in water. Factors affecting its aqueous solubility may include temperature and the pH of the solution.
  • Solvent Compatibility: Ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride tends to be more soluble in polar organic solvents, which may facilitate its use in organic reactions.
  • Effect of Hydrochloride: The presence of the hydrochloride group often enhances solubility in aqueous environments, typically improving its bioavailability.

In general, solubility is a complex property influenced by molecular interactions, and for compounds like ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride, achieving optimal solubility can be key to unlocking their full potential in pharmaceutical and chemical applications.

Interesting facts

Interesting Facts about Ethyl N-(Phthalazin-1-ylamino)carbamate Hydrochloride

Ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride is a fascinating compound with a unique set of characteristics. Here are some points that make it particularly interesting:

  • Pharmaceutical Applications: This compound is known for its potential in medicinal chemistry, particularly in drug development for various biological targets.
  • Structure and Reactivity: The presence of the phthalazine moiety suggests intriguing reactivity patterns, such as the ability to form strong hydrogen bonds, which are crucial in drug-receptor interactions.
  • Versatile Chemistry: Ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride serves as a valuable building block in synthetic organic chemistry, allowing for the creation of more complex molecules.
  • Toxicology and Safety: As with many nitrogen-containing compounds, understanding the toxicological profiles is essential. Studies often emphasize safe handling and usage protocols in laboratory settings.

Moreover, it’s pertinent to note how compounds like this can serve as prodrugs, which are designed to improve pharmacokinetics and bioavailability in therapeutic applications.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” This certainly rings true in the case of ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride, reflecting the continuous exploration of its chemical properties and potential applications in science.

Synonyms
Todralazine hydrochloride
3778-76-5
621-BT hydrochloride
CCRIS 5090
C59540FEXP
Todralazine hydrochloride [JAN]
DTXSID4044664
CARBAZIC ACID, 3-(1-PHTHALAZINYL)-, ETHYL ESTER, MONOHYDROCHLORIDE
N1-Ethoxy carbonyl-N2-hydrazinophthalazine hydrochloride
DTXCID2024664
TODRALAZINE HYDROCHLORIDE [MI]
ANHYDROUS TODRALAZINE HYDROCHLORIDE
TODRALAZINE HYDROCHLORIDE ANHYDROUS
TODRALAZINE HYDROCHLORIDE [WHO-DD]
Ethyl 3-(phthalazin-1-yl)carbazate hydrochloride
ANHYDROUS TODRALAZINE HYDROCHLORIDE [MART.]
ANHYDROUS TODRALAZINE HYDROCHLORIDE (MART.)
622-774-4
Todralazine (hydrochloride)
Ecarazine hydrochloride
Ecarazine (hydrochloride)
ethyl N-(phthalazin-1-ylamino)carbamate;hydrochloride
Ethyl 2-(phthalazin-1-yl)hydrazinecarboxylate hydrochloride
Apirachol
Binazine
Hydrazinecarboxylicacid, 2-(1-phthalazinyl)-, ethyl ester, hydrochloride (1:1)
SR-01000841205
NCGC00016640-03
CAS-3778-76-5
UNII-C59540FEXP
Prestwick_899
MLS002154190
SCHEMBL211261
SPECTRUM1501174
ethyl N-(phthalazin-1-ylamino)carbamate,hydrochloride
CHEMBL1318529
HY-B1001A
HMS1568O03
HMS1921N09
Pharmakon1600-01501174
Tox21_113562
Tox21_301437
CCG-40263
NSC757868
AKOS015963889
AKOS024375001
Tox21_113562_1
NCGC00016640-06
NCGC00094919-01
NCGC00094919-02
NCGC00256213-01
AC-18055
DA-58642
MS-23798
SMR001233481
CS-0098222
D01951
G12148
Q9358993
SR-01000841205-2
SR-01000841205-3
Ethyl2-(phthalazin-1-yl)hydrazinecarboxylatehydrochloride
ethyl 2-(phthalazin-1-yl)hydrazine-1-carboxylate hydrochloride