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Ethyl isonicotinate

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Identification
Molecular formula
C8H9NO2
CAS number
2114-39-8
IUPAC name
ethyl pyridine-2-carboxylate
State
State

At room temperature, ethyl isonicotinate is found in the liquid state.

Melting point (Celsius)
-13.00
Melting point (Kelvin)
260.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
151.16g/mol
Molar mass
151.1730g/mol
Density
1.0996g/cm3
Appearence

Ethyl isonicotinate appears as a colorless to pale yellow liquid. It typically has a characteristic odor and is used mainly in chemical synthesis and industrial applications.

Comment on solubility

Solubility of Ethyl Pyridine-2-Carboxylate

Ethyl pyridine-2-carboxylate, with the chemical formula C8H9NO2, is known for its intriguing solubility characteristics. Its solubility largely depends on the following factors:

  • Polarity: The presence of the carboxylate group contributes to some degree of polarity, allowing ethyl pyridine-2-carboxylate to be soluble in polar solvents.
  • Hydrophobic nature: The ethyl group provides a hydrophobic character which influences its solubility in non-polar solvents.
  • Solvent interaction: It tends to dissolve better in solvents such as ethanol and water, while exhibiting limited solubility in hydrocarbons.

In summary, it can be said that:

  1. Ethyl pyridine-2-carboxylate is more soluble in polar solvents than in non-polar solvents.
  2. Its unique structure allows it to interact with various solvent types, enhancing its versatility in chemical reactions.

Understanding the solubility of ethyl pyridine-2-carboxylate is crucial for applications in organic synthesis and pharmaceuticals.

Interesting facts

Interesting Facts about Ethyl Pyridine-2-carboxylate

Ethyl pyridine-2-carboxylate is a fascinating compound that plays a versatile role in both chemical synthesis and organic chemistry applications. Known for its unique structure, this compound is primarily derived from pyridine, which is a heterocyclic aromatic compound.

Key Characteristics

  • Building Block: Ethyl pyridine-2-carboxylate serves as an important building block for the synthesis of various pharmaceutical and agrochemical products. It is often utilized in the creation of more complex organic compounds.
  • Versatility: The presence of the ethyl group and the carboxylate moiety contributes to its reactivity, enabling it to participate in several chemical reactions, including esterification and acylation.
  • Biological Activity: Research has indicated that compounds containing pyridine rings, such as ethyl pyridine-2-carboxylate, may exhibit interesting biological properties, making them candidates for drug discovery.

Cultural and Historical Significance

Historically, pyridine compounds were synthesized in the 19th century and have since evolved into a vital part of medicinal chemistry. Ethyl pyridine-2-carboxylate represents a modern evolution in the study of heterocyclic compounds.

In the Lab

In the laboratory, this compound is often used in reactions that form more complex molecules. Its ability to act as a reagent or catalyst showcases the compound's importance in organic transformations. As noted by chemists, "the pyridine ring provides stability while the carboxylate group permits functionalization," emphasizing its dual utility.

In summary, ethyl pyridine-2-carboxylate is not just another compound; it stands at the intersection of organic chemistry, pharmaceutical research, and industrial applications, making it a significant subject of study in modern science.

Synonyms
ETHYL PICOLINATE
Ethyl 2-picolinate
Ethyl pyridine-2-carboxylate
Ethyl 2-pyridinecarboxylate
2-Picolinic acid ethyl ester
2-Pyridinecarboxylic acid, ethyl ester
2-(Ethoxycarbonyl)pyridine
Picolinic acid, ethyl ester
2-pyridinecarboxylic acid ethyl ester
RW5EU98AZQ
NSC 959
NSC-959
EINECS 219-758-0
NSC 31651
NSC-31651
DTXSID9062489
DTXCID9037246
fqyyipzpelsldk-uhfffaoysa-n
2524-52-9
Picolinic acid ethyl ester
MFCD00006292
Pyridine-2-carboxylic Acid Ethyl Ester
Pyridinecarboxylic acid, ethyl ester
Ethyl2-picolinate
UNII-RW5EU98AZQ
ethyl pyridin-2-carboxylate
Ethyl 2-picolinate, 99%
SCHEMBL126181
NSC959
CHEMBL2251607
BCP25791
NSC31651
STR01170
BBL036381
STL558973
AKOS008948057
CS-W008053
FP27037
FS-3192
AC-22481
SY020537
DB-046651
NS00027841
P1026
Ethyl 2-picolinate, purum, >=99.0% (GC)
F0001-0852
2-Pyridinecarboxylic acid ethyl ester;Ethyl pyridine-2-carboxylate;2-(Ethoxycarbonyl)pyridine