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Ethyl isonicotinate

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Identification
Molecular formula
C8H9NO2
CAS number
2051-49-2
IUPAC name
ethyl pyridine-4-carboxylate
State
State

Ethyl isonicotinate is typically found in the liquid state at room temperature.

Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
236.00
Boiling point (Kelvin)
509.15
General information
Molecular weight
151.17g/mol
Molar mass
151.1740g/mol
Density
1.0900g/cm3
Appearence

Ethyl isonicotinate appears as a colorless to pale-yellow liquid. It has a characteristic aromatic odor that is similar to other pyridine derivatives. It can darken in color upon exposure to air and light.

Comment on solubility

Solubility of Ethyl Pyridine-4-Carboxylate

Ethyl pyridine-4-carboxylate, a compound with the formula C9H9NO2, exhibits noteworthy solubility characteristics that are essential for its applications in various chemical reactions. When considering its solubility, several factors come into play:

  • Solvent Polarity: Ethyl pyridine-4-carboxylate is notably soluble in polar solvents such as water and alcohols due to its ability to form hydrogen bonds.
  • Hydrophobic and Hydrophilic Interactions: The ethyl group imparts some hydrophobic character, while the carboxylate group enhances its hydrophilic interactions, allowing for effective dissolution in mixed solvent environments.
  • Concentration Effects: At higher concentrations, saturation can occur, which may limit solubility. It is essential to refer to solubility curves for precise data.
  • Temperature Influence: Increased temperature generally improves solubility, making it easier for ethyl pyridine-4-carboxylate to dissolve in various solvents.

In conclusion, the solubility of ethyl pyridine-4-carboxylate is enhanced by its structural features and external conditions. As described, understanding these solubility dynamics fosters better utilization in practical applications and research. To quote a relevant maxim in chemistry: "Like dissolves like," highlighting the significance of matching solvent and solute properties for optimal solubility.

Interesting facts

Interesting Facts About Ethyl Pyridine-4-Carboxylate

Ethyl pyridine-4-carboxylate is a fascinating compound with a range of applications and properties that make it noteworthy in the field of chemistry. Here are some compelling aspects to consider:

  • Chemical Structure: This compound features a pyridine ring substituted with a carboxylate group and an ethyl group, enhancing its reactivity and properties.
  • Versatile Building Block: Ethyl pyridine-4-carboxylate serves as a versatile intermediate in organic synthesis, paving the way for the creation of various biologically active molecules.
  • Pharmaceutical Applications: The unique structure allows for study and modification, making it a candidate for developing pharmaceuticals, particularly in the fields of anti-inflammatory and antimicrobial agents.
  • Interest in Green Chemistry: Its utility in sustainable practices is under investigation, as researchers explore eco-friendly pathways for synthesis using this compound.
  • Reactivity: The functional groups present in ethyl pyridine-4-carboxylate enable it to undergo various reactions, including esterification and acyl substitutions, which are fundamental to building complex organic molecules.

In summary, ethyl pyridine-4-carboxylate represents more than just a simple chemical compound; it embodies a hub of possibilities in chemical synthesis and pharmaceutical research. As scientists continue to explore its properties and potential, this compound stands as an important subject of study in both academia and industry.

Synonyms
ETHYL ISONICOTINATE
4-Pyridinecarboxylic acid, ethyl ester
4-Carbethoxypyridine
Ethyl 4-pyridinecarboxylate
Isonicotinic acid, ethyl ester
4-Carboethoxypyridine
ONG7XTI4BL
gamma-Pyridinecarboxylic acid ethyl ester
NSC 6854
EINECS 216-379-2
BRN 0122942
AI3-22194
.gamma.-Pyridinecarboxylic acid ethyl ester
UNII-ONG7XTI4BL
NSC-6854
4-ETHOXYCARBONYLPYRIDINE
DTXSID6061789
EC 216-379-2
5-22-02-00190 (Beilstein Handbook Reference)
DTXCID4035043
216-379-2
mcrpkbufxakdki-uhfffaoysa-n
1570-45-2
ethyl pyridine-4-carboxylate
4-Picolinic acid ethyl ester
Isonicotinic acid ethyl ester
4-pyridinecarboxylic acid ethyl ester
MFCD00006428
Ethylisonicotinate
Ethyl isonicotinate, 98%
WLN: T6NJ DVO2
pyridine, 4-ethoxycarbonyl-
SCHEMBL24935
CHEMBL2251613
NSC6854
HMS1754D18
BAA57045
BBL013187
STL163966
AKOS001058465
CS-W020597
AC-22479
AS-17585
SY001919
DB-012900
I0137
NS00004261
Ethyl isonicotinate, purum, >=99.0% (GC)
D70811
EN300-176600
Z53833081
F0001-0560