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Thiomersal

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Identification
Molecular formula
C9H9HgNaO2S
CAS number
54-64-8
IUPAC name
ethylmercury;ethylmercury(1+);sulfanide
State
State

At room temperature, Thiomersal is generally considered to be in a solid state, owing to its crystalline structure. It can also be found in solution forms as part of pharmaceutical formulations.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
927.00
Boiling point (Kelvin)
1 200.15
General information
Molecular weight
404.82g/mol
Molar mass
404.8180g/mol
Density
2.4000g/cm3
Appearence

Thiomersal typically appears as a white to slightly yellow crystalline powder. In some formulations, particularly in aqueous solutions, it might appear as a colorless liquid. The compound is used as a preservative in pharmaceuticals and vaccines, providing antimicrobial activity.

Comment on solubility

Solubility of Ethylmercury Sulfanide

Ethylmercury sulfanide (C9H9HgNaO2S) exhibits unique solubility characteristics that are noteworthy in various chemical contexts. Understanding its solubility can offer insights into its reactivity and application potentials. Here are some key points regarding its solubility:

  • Solvent Compatibility: Ethylmercury sulfanide is generally soluble in organic solvents such as alcohols and ethers, but its solubility in water is quite low.
  • Influence of pH: The solubility may vary with pH; in acidic conditions, the solubility could potentially increase due to the formation of stable ionic species.
  • Temperature Dependence: Like many compounds, an increase in temperature may enhance the solubility of ethylmercury sulfanide, allowing for greater dissolution.
  • Complex Formation: Ethylmercury can form complexes with various ligands, which enhances its solubility in certain environments, potentially affecting its bioavailability and toxicity.

In general, due to its unique composition, ethylmercury sulfanide shows a tendency for low aqueous solubility, which may limit its use in certain aqueous-based systems. As a reminder, attention should be given to safety and environmental factors when handling compounds containing mercury, as they can be hazardous.

Interesting facts

Interesting Facts about Ethylmercury Sulfanide

Ethylmercury sulfanide is a fascinating organomercury compound with intriguing properties and applications. Here are some noteworthy points about this compound:

  • Clinical Use: Ethylmercury has been used in medical applications, particularly as a preservative in vaccines, often seen under the trade name thimerosal. This has led to extensive discussions regarding safety and efficacy.
  • Environmental Impact: Like many mercury compounds, ethylmercury can pose significant environmental risks. Its accumulation in aquatic ecosystems can lead to toxicity in marine life, making the monitoring of its discharge crucial.
  • Comparative Chemistry: Ethylmercury differs from methymercury in terms of stability and toxicity. While both are organomercury compounds, studies indicate differing behaviors in biological systems, with ethylmercury generally showing a more rapid elimination from the human body.
  • Analytical Chemistry: The detection of ethylmercury is essential in laboratory settings, leading to the development of advanced analytical techniques. Methods like gas chromatography coupled with mass spectrometry (GC-MS) are often employed for its quantification.
  • Regulatory Overview: The use of ethylmercury and compounds containing mercury is subject to strict regulations due to concerns about mercury exposure. Regulatory agencies continuously review available data to assess safety thresholds.
  • Historical Context: Ethylmercury and its derivatives have not only medical applications but also a historical significance in understanding mercury's role in toxicology. The evolution of its use reflects the broader changes in scientific understanding of mercury's effects on health.

As scientists and students of chemistry continue to explore the properties and effects of ethylmercury sulfanide, it remains an essential compound in discussions about public health, environmental science, and regulatory policies.