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Deferoxamine mesylate

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Identification
Molecular formula
C25H48N6O8
CAS number
138-14-7
IUPAC name
ferric;N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide
State
State

At room temperature, deferoxamine mesylate is stable in its solid state as a powder. However, it is highly soluble in water and can be easily prepared as a solution for intravenous administration.

Melting point (Celsius)
134.50
Melting point (Kelvin)
407.65
Boiling point (Celsius)
557.80
Boiling point (Kelvin)
830.95
General information
Molecular weight
560.69g/mol
Molar mass
560.6870g/mol
Density
1.0100g/cm3
Appearence

Deferoxamine mesylate typically appears as an off-white or pinkish-white powder. When dissolved, it forms a clear solution with a slightly yellowish hue. It is hygroscopic and freely soluble in water, which makes it ideal for medicinal injections.

Comment on solubility

Solubility of Ferric N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide

The solubility of the compound Ferric N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide can be influenced by several factors. Understanding the solubility behavior of this complex compound is essential for its applications in various fields.

Factors Influencing Solubility

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while non-polar regions may hinder it.
  • pH Level: Changes in pH can affect the ionization of groups within the compound, thereby affecting overall solubility.
  • Temperature: Higher temperatures typically increase solubility for many compounds, though this is not universally true.
  • Solvent Characteristics: The choice of solvent plays a pivotal role; solubility is often highest in solvents that mimic the polarity of the compound.

General Observations

In general, amphiphilic compounds can exhibit improved solubility in both polar and non-polar environments. For instance, compounds with multiple functional groups can facilitate interactions between solute and solvent molecules, promoting solubility. However, if the compound has substantial hydrophobic sections, it may remain poorly soluble in aqueous environments.

To summarize, while the precise solubility of Ferric N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide can be complex and variable, understanding these factors is crucial for predicting its behavior in solution.

Interesting facts

Interesting Facts about Ferric N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide

Ferric N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide is a fascinating compound that showcases the remarkable versatility of coordination chemistry and the integration of biologically significant elements. Here are some interesting points about this complex molecule:

  • Complex Architecture: This compound contains an intricate structure with multiple functional groups, including a hexazacyclooctadecane framework, which is pivotal in developing drugs that target metal ions in biological systems.
  • Biomimetic Design: The design of this compound reflects biomimetic strategies, which aim to mimic natural biological processes. Such compounds can potentially facilitate drug delivery or act as therapeutic agents in treating diseases.
  • Oxidation States: The ferric (Fe3+) component plays a critical role in redox chemistry, making it important in various biochemical pathways, including electron transport chains within cells.
  • Coordination Chemistry: The ability of the nitrogen and oxygen atoms to coordinate with the iron atom opens pathways for studying how ligands can affect the reactivity and stability of metal ions in solution.
  • A Potential in Therapeutics: Compounds like this may have potential applications in targeted therapies, especially in cancer treatment where metal-based compounds have shown efficacy.

As a compound that illustrates the intricate relationship between organic chemistry and metallomics, Ferric N-[3-[5,8-bis[3-[acetyl(oxido)amino]propyl]-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propyl]-N-oxido-acetamide represents the fusion of synthetic chemistry and biological relevance. Its investigation can deepen our understanding of how complex ligands interact with metal centers, paving the way for innovative therapeutic strategies.

Synonyms
SCHEMBL41659
GGUNGDGGXMHBMJ-UHFFFAOYSA-N
Q1998031